Abstract: Aspects of the disclosure relate to an adjustable implant configured to be implanted into a patient that includes an adjustable portion moveable relative to a housing. The adjustable implant may include various smart components for enhancing operation of the implant. Smart components may include a controller for managing operations and a transducer for communicating ultrasound data with an external interface device. Additional smart components may include a load cell within the housing for measuring an imparted load; a sensor for measuring angular position of the adjustable portion; a dual sensor arrangement for measuring imparted forces; a reed switch; a half piezo transducer; and an energy harvester.

Abstract: Various implementations include implants and related methods for moving bone. Certain implementations include an implant for moving bone in a patient's body, the implant including: an implantable biocompatible housing; a first adjustment rod at least partially overlapping the implantable biocompatible housing; a driver configured to drive the first adjustment rod to enable movement of the first adjustment rod relative to the housing; and a load sensor positioned within the housing and configured to indicate a load applied by the driver on the first adjustment rod.

Abstract: Aspects of the disclosure relate to an adjustable implant configured to be implanted into a patient that includes an adjustable portion moveable relative to a housing. The adjustable implant may include various smart components for enhancing operation of the implant. Smart components may include a controller for managing operations and a transducer for communicating ultrasound data with an external interface device. Additional smart components may include a load cell within the housing for measuring an imparted load; a sensor for measuring angular position of the adjustable portion; a dual sensor arrangement for measuring imparted forces; a reed switch; a half piezo transducer; and an energy harvester.

Abstract: An apparatus for a lateral flow nucleic acid assay with an integrated pore-based detector, which has the potential to detect pathogens, both microbial and viral, in aqueous samples in approximately 5 minutes or less without nucleic acid amplification or optical components. The detector is based on an electromechanical signal transduction mechanism that enables low-cost detection of DNA/RNA at ultralow concentrations (down to about 10 M to about 19 M). The scheme relies on the use of charge-neutral peptide nucleic acid (PNA) capture probe conjugated to polystyrene beads. The PNA-beads acquire substantial negative charge upon capture of target pathogenic DNA/RNA and become mobile in an electric field. Upon application of a bias voltage of around 1 V to 2 V, the PNA-beads with hybridized target are directed electrophoretically to a smaller diameter pore. Subsequent pore blockage results in a strong, sustained drop in measured ionic current through the pore.

Abstract: Systems and related methods for changing the angle of a bone of a subject is provided by the present disclosure. The system may include a non-invasively adjustable implant configured to be placed inside a cavity within the bone. The non-invasively adjustable implant may couple to a first portion of bone and a second portion of bone that is separated or separable from the first portion of bone, such that non-invasive elongation of the adjustable implant causes movement of the first portion of bone and the second portion of bone apart angularly. The system may include an anchor configured to couple the non-invasively adjustable implant to bone. The non-invasively adjustable implant may include an anchor hole configured to receive the anchor therein.

Abstract: The present disclosure provides implants, sensor modules, networks, and methods configured to establish transcutaneous power and transcutaneous bidirectional data communication using ultrasound signals between two or more medical devices located on and within a body of a patient.

Abstract: A system, and method of using the system, for changing the angle of a bone of a subject is provided by the present disclosure.

Abstract: The present disclosure provides implants, sensor modules, networks, and methods configured to establish transcutaneous power and transcutaneous bidirectional data communication using ultrasound signals between two or more medical devices located on and within a body of a patient.

Abstract: An endoscope includes a housing with a distal end insertable into a cavity; an image capture device at the distal end to obtain 3D images, and process them to form a video signal; and a folded substrate folded into a U-shape having first and second legs. The image capture device includes a detector and a lens system with right and left multi-band pass filters having right pass bands that are complements of left pass bands. The lens system receives the 3D images including right and left images. The detector faces the lens system to obtain the right and left images. A processing circuit faces the proximal end behind the detector to process signals from the detector. The folded substrate includes the detector at an outer side of the first leg facing the lens system and the processing circuit at an outer side of the second leg facing the proximal end.

Abstract: An aspect of the disclosure relates to an intramedullary device configured for ankle fusion. The intramedullary device for ankle fusion includes: a housing configured to be coupled to a calcaneus bone; and a rod configured to be coupled to a tibia bone, wherein a distal end of the housing includes an external thread. The rod is configured for telescopic movement relative to the housing, and to retract relative to the housing to cause ankle fusion. After fusion is achieved, the rod can be distracted to correct a limb length discrepancy.

Abstract: This disclosure concerns devices and methods for measuring an amount of adjustment of an expandable implant using ultrasound. The implant may include an ultrasound counter including a vibration element tuned for ultrasonic vibration, the vibration element may be configured to produce an ultrasound vibration upon an adjustment of the expandable implant.

Abstract: Aspects of the disclosure relate to an adjustable implant configured to be implanted into a patient that includes an adjustable portion moveable relative to a housing. The adjustable implant may include various smart components for enhancing operation of the implant. Smart components may include a controller for managing operations and a transducer for communicating ultrasound data with an external interface device. Additional smart components may include a load cell within the housing for measuring an imparted load; a sensor for measuring angular position of the adjustable portion; a dual sensor arrangement for measuring imparted forces; a reed switch; a half piezo transducer; and an energy harvester.

Abstract: Various implementations include apparatuses and methods for subcutaneous sensing. Certain implementations include an apparatus having: a biocompatible housing defining a longitudinal axis; a subcutaneous sensor; a circuit board; a controller; and an ultrasound transmitter disposed within the biocompatible housing and including a tubular piezoelectric transducer extending longitudinally along the longitudinal axis.

Abstract: Aspects of the disclosure relate to an adjustable implant configured to be implanted into a patient that includes an adjustable portion moveable relative to a housing. The adjustable implant may include various smart components for enhancing operation of the implant. Smart components may include a controller for managing operations and a transducer for communicating ultrasound data with an external interface device. Additional smart components may include a load cell within the housing for measuring an imparted load; a sensor for measuring angular position of the adjustable portion; a dual sensor arrangement for measuring imparted forces; a reed switch; a half piezo transducer; and an energy harvester.

Abstract: Aspects of the disclosure relate to an adjustable implant configured to be implanted into a patient that includes an adjustable portion moveable relative to a housing. The adjustable implant may include various smart components for enhancing operation of the implant. Smart components may include a controller for managing operations and a transducer for communicating ultrasound data with an external interface device. Additional smart components may include a load cell within the housing for measuring an imparted load; a sensor for measuring angular position of the adjustable portion; a dual sensor arrangement for measuring imparted forces; a reed switch; a half piezo transducer; and an energy harvester.

Abstract: Aspects of the disclosure relate to an adjustable implant configured to be implanted into a patient that includes an adjustable portion moveable relative to a housing. The adjustable implant may include various smart components for enhancing operation of the implant. Smart components may include a controller for managing operations and a transducer for communicating ultrasound data with an external interface device. Additional smart components may include a load cell within the housing for measuring an imparted load; a sensor for measuring angular position of the adjustable portion; a dual sensor arrangement for measuring imparted forces; a reed switch; a half piezo transducer; and an energy harvester.

Abstract: Aspects of the disclosure relate to an adjustable implant configured to be implanted into a patient that includes an adjustable portion moveable relative to a housing. The adjustable implant may include various smart components for enhancing operation of the implant. Smart components may include a controller for managing operations and a transducer for communicating ultrasound data with an external interface device. Additional smart components may include a load cell within the housing for measuring an imparted load; a sensor for measuring angular position of the adjustable portion; a dual sensor arrangement for measuring imparted forces; a reed switch; a half piezo transducer; and an energy harvester.

Abstract: An implantable device for sensing data includes a subcutaneous sensor configured to couple with an implant. The implantable device is operably configured to wirelessly and transcutaneously transmit data sensed by the subcutaneous sensor. The sensor may be powered wirelessly and transcutaneously. Transmission of data and/or power may be provided by ultrasound sound waves. The sensor may be in electrical communication with a piezoelectric transducer configured to receive the ultrasound sound waves.

Abstract: The present disclosure broadly provides applications of communication at ultrasound frequencies to establish transcutaneous data communication between medical devices located on and/or within a body of a patient, including inter alia: features for adjustable implants including data communication, hermetic containment, and torque amplification features.

Abstract: The present disclosure provides an external transceiver configured for ultrasonic communication with a medical implant, the external transceiver including an array of ultrasonic transducers configured to be placed adjacent to a patient's skin and each ultrasonic transducer of the array of ultrasonic transducers configured to send and receive an ultrasonic signal.