Patents by Inventor Yousef F. Alkhatib
Yousef F. Alkhatib has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11141267Abstract: A prosthetic aortic valve includes an annular, annulus inflow portion that is designed to reside in or near the patient's native aortic valve annulus, and an annular, aortic outflow portion that is designed to reside in the patient's aorta downstream from at least a portion of the valsalva sinus. The annulus inflow portion and the aortic outflow portion are connected to one another by a plurality of connecting struts that are confined to regions near the commissures of the patient's native aortic valve. The connecting struts are designed to bulge out into the valsalva sinus to help anchor the prosthetic valve in place. The valve is circumferentially collapsible to a relatively small diameter for less-invasive delivery into the patient. The valve circumferentially expands to a larger operational diameter when deployed at the implant site.Type: GrantFiled: October 17, 2019Date of Patent: October 12, 2021Assignee: St. Jude Medical, LLCInventor: Yousef F. Alkhatib
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Patent number: 11045314Abstract: A prosthetic heart valve includes a stent having an expanded condition and a collapsed condition. The stent includes a plurality of distal cells, a plurality of proximal cells, a plurality of support struts coupling the proximal cells to the distal cells, and at least one support post connected to a plurality of proximal cells. The proximal cells are longitudinally spaced apart from the distal cells. Various strut configurations and connections of the struts to the proximal cells and of the proximal cells to the support post improve stent flexibility and reduce stress in the valve leaflets.Type: GrantFiled: September 6, 2019Date of Patent: June 29, 2021Assignee: St. Jude Medical, LLCInventors: Peter N. Braido, Yousef F. Alkhatib, Thomas M. Benson, Aaron J. Chalekian, Ott Khouengboua, Julia A. Schraut
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Patent number: 11013596Abstract: Prosthetic heart valve apparatus is adapted for delivery into a patient in a circumferentially collapsed condition, followed by circumferential re-expansion at the implant site in the patient. The apparatus includes an annular anchoring structure that can be implanted in the patient first. The apparatus further includes an annular valve support structure, which supports a flexible leaflet structure of the valve. The support and leaflet structures are initially separate from the anchoring structure, but they can be implanted in the patient by interengagement of the support structure with the already-implanted anchoring structure.Type: GrantFiled: April 15, 2019Date of Patent: May 25, 2021Assignee: St. Jude Medical, LLCInventor: Yousef F. Alkhatib
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Publication number: 20210121290Abstract: At least a portion of sheet materials for use in medical devices is formed from polymeric materials. The sheet materials may be partially coated or fully coated with one or more additional layers of a polymer. The sheet materials may be used for the leaflets and/or cuffs of prosthetic heart valves and as a component of other medical devices.Type: ApplicationFiled: June 11, 2020Publication date: April 29, 2021Applicant: Abbott LaboratoriesInventors: Yousef F. Alkhatib, Jay Reimer, Paul E. Ashworth, Keith T. High
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Patent number: 10874510Abstract: A prosthetic heart valve may include a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end, and a plurality of cells connected to one another in annular rows around the stent, a cuff attached to the stent, and a sealing member attached to the cuff and extending from a proximal end of the cuff to a free edge. The sealing member may be movable between an extended condition in which the free edge is located proximally of the proximal end of the stent, and an inverted condition in which the free edge is located distally of the proximal end of the stent and a first surface of the sealing member confronts an outward-facing surface of the cuff. Various mechanisms for moving the sealing member are also described.Type: GrantFiled: October 30, 2018Date of Patent: December 29, 2020Assignee: St. Jude Medical, Cardiology Division, Inc.Inventors: Peter N. Braido, Yousef F. Alkhatib, Steven Frederick Anderl, Jacob John Daly, Mina S. Fahim, Kent J. Smith, Ralph Joseph Thomas
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Publication number: 20200397577Abstract: A guidewire may be configured for insertion into a heart of a patient during a procedure such as a transcatheter aortic valve replacement procedure. The guidewire may include a proximal end and a distal end portion. The distal end portion may include (i) a leading section, (ii) a loop structure at a terminal distal end of the guidewire, and (iii) a transition section extending between the leading section and the loop structure. In the absence of applied forces, the leading section is not tangential to the loop structure. With such a configuration, the guidewire may avoid contact with the ventricular septum of the heart when the loop structure is seated within the left ventricle, which may mitigate potential interference with conduction pathways in the ventricular septum, which may in turn mitigate the need for a pacemaker.Type: ApplicationFiled: June 18, 2020Publication date: December 24, 2020Applicant: St. Jude Medical, Cardiology Division, Inc.Inventors: Yousef F. Alkhatib, Michael Shane Morrissey, Jay Reimer, Kristopher Henry Vietmeier, Peter J. Ness
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Publication number: 20200323630Abstract: At least a portion of fabrics for use in medical devices is formed from polymeric materials. The fabrics may be uncoated, partially coated or fully coated with one or more layers of a polymer. The fabrics may be used for the leaflets and/or cuffs of prosthetic heart valves and as a component of other medical devices.Type: ApplicationFiled: June 11, 2020Publication date: October 15, 2020Applicant: Abbott LaboratoriesInventors: Yousef F. Alkhatib, Jay Reimer, Paul E. Ashworth, Keith T. High, Richard Kaleta, Ryan Finn
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Publication number: 20200188098Abstract: At least a portion of fabrics for use in medical devices is formed from polymeric materials. The fabrics may be uncoated, partially coated or fully coated with one or more layers of a polymer. The fabrics may be used for the leaflets and/or cuffs of prosthetic heart valves and as a component of other medical devices.Type: ApplicationFiled: December 13, 2019Publication date: June 18, 2020Applicant: Abbott LaboratoriesInventors: Yousef F. Alkhatib, Jay Reimer, Paul E. Ashworth, Keith T. High, Richard Kaleta, Ryan Finn
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Publication number: 20200138574Abstract: A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent having a proximal end and a distal end, and a valve assembly including a plurality of leaflets, the valve assembly being disposed within the stent. The heart valve further includes a first plurality of elongated legs coupled to the stent and transitionable from an extended configuration to a relaxed configuration. A first sealing portion connected to the first plurality of legs forms a sealing structure when the legs transition to the relaxed configuration to reduce perivalvular leakage between the implanted valve and surrounding tissue.Type: ApplicationFiled: December 17, 2019Publication date: May 7, 2020Applicant: St. Jude Medical, Cardiology Division, Inc.Inventors: Yousef F. Alkhatib, Tracee Eidenschink, Sounthara Khouengboua
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Publication number: 20200078169Abstract: A collapsible prosthetic heart valve includes a collapsible and expandable stent and a collapsible and expandable valve assembly. The stent has a proximal end and a distal end. A plurality of commissure points is disposed on the stent. The valve assembly is disposed within the stent and includes a plurality of leaflets. Each leaflet has a free edge. An end portion of the free edge of each leaflet is folded and sutured to a corresponding one of the plurality of the commissure points.Type: ApplicationFiled: November 14, 2019Publication date: March 12, 2020Applicant: St. Jude Medical, Cardiology Division, Inc.Inventors: Yousef F. Alkhatib, Peter N. Braido
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Publication number: 20200046494Abstract: A prosthetic aortic valve includes an annular, annulus inflow portion that is designed to reside in or near the patient's native aortic valve annulus, and an annular, aortic outflow portion that is designed to reside in the patient's aorta downstream from at least a portion of the valsalva sinus. The annulus inflow portion and the aortic outflow portion are connected to one another by a plurality of connecting struts that are confined to regions near the commissures of the patient's native aortic valve. The connecting struts are designed to bulge out into the valsalva sinus to help anchor the prosthetic valve in place. The valve is circumferentially collapsible to a relatively small diameter for less-invasive delivery into the patient. The valve circumferentially expands to a larger operational diameter when deployed at the implant site.Type: ApplicationFiled: October 17, 2019Publication date: February 13, 2020Applicant: St. Jude Medical, LLCInventor: Yousef F. Alkhatib
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Patent number: 10548725Abstract: A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent having a proximal end and a distal end, and a valve assembly including a plurality of leaflets, the valve assembly being disposed within the stent. The heart valve further includes a first plurality of elongated legs coupled to the stent and transitionable from an extended configuration to a relaxed configuration. A first sealing portion connected to the first plurality of legs forms a sealing structure when the legs transition to the relaxed configuration to reduce perivalvular leakage between the implanted valve and surrounding tissue.Type: GrantFiled: December 8, 2017Date of Patent: February 4, 2020Assignee: St. Jude Medical, Cardiology Division, Inc.Inventors: Yousef F. Alkhatib, Tracee Eidenschink, Sounthara Khouengboua
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Publication number: 20190388224Abstract: A prosthetic heart valve includes a stent having an expanded condition and a collapsed condition. The stent includes a plurality of distal cells, a plurality of proximal cells, a plurality of support struts coupling the proximal cells to the distal cells, and at least one support post connected to a plurality of proximal cells. The proximal cells are longitudinally spaced apart from the distal cells. Various strut configurations and connections of the struts to the proximal cells and of the proximal cells to the support post improve stent flexibility and reduce stress in the valve leaflets.Type: ApplicationFiled: September 6, 2019Publication date: December 26, 2019Applicant: St. Jude Medical, LLCInventors: Peter N. Braido, Yousef F. Alkhatib, Thomas M. Benson, Aaron J. Chalekian, Ott Khouengboua, Julia A. Schraut
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Patent number: 10512538Abstract: A collapsible prosthetic heart valve includes a collapsible and expandable stent and a collapsible and expandable valve assembly. The stent has a proximal end and a distal end. A plurality of commissure points is disposed on the stent. The valve assembly is disposed within the stent and includes a plurality of leaflets. Each leaflet has a free edge. An end portion of the free edge of each leaflet is folded and sutured to a corresponding one of the plurality of the commissure points.Type: GrantFiled: June 28, 2017Date of Patent: December 24, 2019Assignee: St. Jude Medical, Cardiology Division, Inc.Inventors: Yousef F. Alkhatib, Peter N. Braido
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Patent number: 10485662Abstract: A prosthetic aortic valve includes an annular, annulus inflow portion that is designed to reside in or near the patient's native aortic valve annulus, and an annular, aortic outflow portion that is designed to reside in the patient's aorta downstream from at least a portion of the valsalva sinus. The annulus inflow portion and the aortic outflow portion are connected to one another by a plurality of connecting struts that are confined to regions near the commissures of the patient's native aortic valve. The connecting struts are designed to bulge out into the valsalva sinus to help anchor the prosthetic valve in place. The valve is circumferentially collapsible to a relatively small diameter for less-invasive delivery into the patient. The valve circumferentially expands to a larger operational diameter when deployed at the implant site.Type: GrantFiled: March 16, 2018Date of Patent: November 26, 2019Assignee: St. Jude Medical, LLCInventor: Yousef F. Alkhatib
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Patent number: 10441417Abstract: A prosthetic heart valve includes a stent having an expanded condition and a collapsed condition. The stent includes a plurality of distal cells, a plurality of proximal cells, a plurality of support struts coupling the proximal cells to the distal cells, and at least one support post connected to a plurality of proximal cells. The proximal cells are longitudinally spaced apart from the distal cells. Various strut configurations and connections of the struts to the proximal cells and of the proximal cells to the support post improve stent flexibility and reduce stress in the valve leaflets.Type: GrantFiled: January 11, 2018Date of Patent: October 15, 2019Assignee: St. Jude Medical, LLCInventors: Peter N. Braido, Yousef F. Alkhatib, Thomas M. Benson, Aaron J. Chalekian, Ott Khouengboua, Julia A. Schraut
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Patent number: 10405973Abstract: A prosthetic heart valve includes an annular frame that is adapted for (1) delivery into a patient's native heart valve annulus in a circumferentially collapsed condition, and (2) circumferential re-expansion when in the annulus, the frame, in an expanded condition. The frame having a longitudinal axis, an inflow end and an outflow end, a first portion of the frame adjacent the inflow end inclining radially outwardly in a direction toward the inflow end, and a second portion of the frame between the first portion and the outflow end bulging radially outwardly, the second portion of the frame being positioned between a first axial distance from the inflow end and a second axial distance from the inflow end. The frame also includes a plurality of commissure members. The heart valve further includes a flexible leaflet structure disposed in the frame.Type: GrantFiled: March 22, 2017Date of Patent: September 10, 2019Assignee: St. Jude Medical, LLCInventors: Yousef F. Alkhatib, Michael J. Girard
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Publication number: 20190269508Abstract: A prosthetic heart valve (e.g., a prosthetic aortic valve) is designed to be somewhat circumferentially collapsible and then re-expandable. The collapsed condition may be used for less invasive delivery of the valve into a patient. When the valve reaches the implant site in the patient, it re-expands to normal operating size, and also to engage surrounding tissue of the patient. The valve includes a stent portion and a ring portion that is substantially concentric with the stent portion but downstream from the stent portion in the direction of blood flow through the implanted valve. When the valve is implanted, the stent portion engages the patient's tissue at or near the native valve annulus, while the ring portion engages tissue downstream from the native valve site (e.g., the aorta).Type: ApplicationFiled: May 20, 2019Publication date: September 5, 2019Applicant: St. Jude Medical, LLCInventors: Peter N. Braido, Yousef F. Alkhatib
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Patent number: 10388188Abstract: An apparatus for simulation of an anatomical structure may include a left ventricle component having an inlet port configured to receive fluid flow therethrough, an aortic arch component having an outlet port configured to receive fluid flow therethrough, an aortic annulus component attached to and disposed between the left ventricle component and the aortic arch component, and an introducer configured to receive an elongated catheter assembly therethrough. The aortic annulus component may have an inner surface including simulated stenotic nodules. The introducer may be in fluid communication with at least one of the left ventricle component and the aortic arch component.Type: GrantFiled: November 16, 2016Date of Patent: August 20, 2019Assignee: St. Jude Medical, Cardiology Division, Inc.Inventors: Yousef F. Alkhatib, Theodore Paul Dale, Aaron J. Chalekian, James Leo Kurk
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Publication number: 20190240007Abstract: Prosthetic heart valve apparatus is adapted for delivery into a patient in a circumferentially collapsed condition, followed by circumferential re-expansion at the implant site in the patient. The apparatus includes an annular anchoring structure that can be implanted in the patient first. The apparatus further includes an annular valve support structure, which supports a flexible leaflet structure of the valve. The support and leaflet structures are initially separate from the anchoring structure, but they can be implanted in the patient by interengagement of the support structure with the already-implanted anchoring structure.Type: ApplicationFiled: April 15, 2019Publication date: August 8, 2019Applicant: St. Jude Medical, LLCInventor: Yousef F. Alkhatib