Patents by Inventor Yousef TIZABI

Yousef TIZABI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C-terminal fragment of tetanus toxin (HC) for treatment of depression
    Patent number: 12168035
    Abstract: C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) provides therapeutic effects in motor impairments associated with Parkinson disease (PD), and provides long lasting antidepressant effects, thus useful in treating and mitigating depression, particularly PD-depression co-morbid condition. A method for treating or mitigating depression, including administrating an effective amount of C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) to a subject in need thereof. A method for treating or mitigating motor impairments associated with Parkinson's disease (PD), including administrating an effective amount of C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) to a subject in need thereof.
    Type: Grant
    Filed: April 26, 2022
    Date of Patent: December 17, 2024
    Assignee: Howard University
    Inventor: Yousef Tizabi
  • Method for treating or mitigating Parkinson's disease using nicotine inhaler or nicotine nasal spray
    Patent number: 11541004
    Abstract: A method for treating or mitigating Parkinson's disease (PD) symptoms or progression, including administering an effective amount of nicotine to a subject in need thereof, via inhalation using a nicotine inhaler or via nasal spray using a nicotine nasal spray. Significant dose-dependent improvement of all symptoms by nicotine inhaler or nicotine nasal spray is expected. A novel treatment in PD is thus provided.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: January 3, 2023
    Assignee: HOWARD UNIVERSITY
    Inventors: Yousef Tizabi, Robert L. Copeland
  • C-TERMINAL FRAGMENT OF TETANUS TOXIN (HC) FOR TREATMENT OF DEPRESSION
    Publication number: 20220249602
    Abstract: C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) provides therapeutic effects in motor impairments associated with Parkinson disease (PD), and provides long lasting antidepressant effects, thus useful in treating and mitigating depression, particularly PD-depression co-morbid condition. A method for treating or mitigating depression, including administrating an effective amount of C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) to a subject in need thereof. A method for treating or mitigating motor impairments associated with Parkinson's disease (PD), including administrating an effective amount of C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) to a subject in need thereof.
    Type: Application
    Filed: April 26, 2022
    Publication date: August 11, 2022
    Applicant: HOWARD UNIVERSITY
    Inventor: Yousef TIZABI
  • C-terminal fragment of tetanus toxin (Hc) for treatment of depression
    Patent number: 11338016
    Abstract: C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) provides therapeutic effects in motor impairments associated with Parkinson disease (PD), and provides long lasting antidepressant effects, thus useful in treating and mitigating depression, particularly PD-depression co-morbid condition. A method for treating or mitigating depression, including administrating an effective amount of C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) to a subject in need thereof. A method for treating or mitigating motor impairments associated with Parkinson's disease (PD), including administrating an effective amount of C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) to a subject in need thereof.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: May 24, 2022
    Assignee: HOWARD UNIVERSITY
    Inventor: Yousef Tizabi
  • METHOD FOR TREATING OR MITIGATING PARKINSON'S DISEASE USING NICOTINE INHALER OR NICOTINE NASAL SPRAY
    Publication number: 20210386663
    Abstract: A method for treating or mitigating Parkinson's disease (PD) symptoms or progression, including administering an effective amount of nicotine to a subject in need thereof, via inhalation using a nicotine inhaler or via nasal spray using a nicotine nasal spray. Significant dose-dependent improvement of all symptoms by nicotine inhaler or nicotine nasal spray is expected. A novel treatment in PD is thus provided.
    Type: Application
    Filed: June 10, 2020
    Publication date: December 16, 2021
    Applicant: HOWARD UNIVERSITY
    Inventors: Yousef TIZABI, Robert L. COPELAND
  • C-TERMINAL FRAGMENT OF TETANUS TOXIN (HC) FOR TREATMENT OF DEPRESSION
    Publication number: 20210361739
    Abstract: C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) provides therapeutic effects in motor impairments associated with Parkinson disease (PD), and provides long lasting antidepressant effects, thus useful in treating and mitigating depression, particularly PD-depression co-morbid condition. A method for treating or mitigating depression, including administrating an effective amount of C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) to a subject in need thereof. A method for treating or mitigating motor impairments associated with Parkinson's disease (PD), including administrating an effective amount of C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) to a subject in need thereof.
    Type: Application
    Filed: May 20, 2020
    Publication date: November 25, 2021
    Applicant: Howard University
    Inventor: Yousef TIZABI