Patents by Inventor Yousri M. Barri

Yousri M. Barri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prevention and treatment of atherosclerosis by reducing carbamylation of LDL or the effects of carbamylated LDL
    Patent number: 7722858
    Abstract: The present invention provides a method of determining whether an individual is at risk for atherosclerosis, comprising the step of measuring the level of cLDL and/or autoantibody to cLDL in a sample obtained from this individual. The invention further discloses a method of reducing carbamylation in an individual with a monomeric amino acid or other enzymatic or non-enzymatic inhibitors of carbamylation. The instant invention also provides a method to decrease the level of cLDL by direct elimination of cLDL from the blood or plasma of an individual. The invention also provides a method of treating or preventing atherosclerosis in an individual by inhibiting aggregation and/or deposition of cLDL in the individual.
    Type: Grant
    Filed: February 9, 2006
    Date of Patent: May 25, 2010
    Assignees: Board of Trustees of the University of Arkansas, The United States of America as represented by the Department of Veterans Affairs
    Inventors: Sudhir V. Shah, Alexei G. Basnakian, Yousri M. Barri
  • Diagnosing atherosclerosis risk by measuring carbamylated low density lipoprotein levels
    Patent number: 7476551
    Abstract: The present invention provides a method of determining whether an individual is at risk for atherosclerosis, comprising the step of: measuring the level of carbamylated LDL in a sample obtained from said individual. Further provided is a method of reducing carbamylation in an individual in need of such reducing, comprising the step of: treating said individual with a monomeric amino acid or another enzymatic or non-enzymatic inhibitor of carbamylation. Also provided is a method of preventing carbamylation in an individual with normal renal function, comprising the step of: treating said individual with a monomeric amino acid. Further provided is a method of treating or preventing atherosclerosis in an individual in need of such reducing, comprising the step of: inhibiting aggregation and/or deposition of carbamylated LDL in said individual.
    Type: Grant
    Filed: August 27, 2002
    Date of Patent: January 13, 2009
    Assignee: The Board of Trustees of the University of Arkansas
    Inventors: Yousri M. Barri, Sudhir V. Shah, Alexei G. Basnakian
  • Prevention and treatment of atherosclerosis by reducing carbamylation of LDL or the effects of carbamylated LDL
    Publication number: 20030045004
    Abstract: The present invention provides a method of determining whether an individual is at risk for atherosclerosis, comprising the step of: measuring the level of carbamylated LDL in a sample obtained from said individual. Further provided is a method of reducing carbamylation in an individual in need of such reducing, comprising the step of:treating said individual with a monomeric amino acid or another enzymatic or non-enzymatic inhibitor of carbamylation. Also provided is a method of preventing carbamylation in an individual with normal renal function, comprising the step of: treating said individual with a monomeric amino acid. Further provided is a method of treating or preventing atherosclerosis in an individual in need of such reducing, comprising the step of: inhibiting aggregation and/or deposition of carbamylated LDL in said individual.
    Type: Application
    Filed: August 27, 2002
    Publication date: March 6, 2003
    Inventors: Yousri M. Barri, Sudhir V. Shah, Alexei G. Basnakian