Patents by Inventor Yousuke Ebina

Yousuke Ebina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110014626
    Abstract: Presence of free insulin receptor ?-subunit in blood was discovered. Furthermore, methods for measuring the insulin receptor ?-subunit was provided, the method comprising the steps of contacting the insulin receptor ?-subunit in a blood sample with an antibody recognizing the insulin receptor ?-subunit, and detecting the binding between the two. Measurement of the free insulin receptor ?-subunit in the blood is useful for evaluating risk factors for diabetes. In addition, the measurement methods of the present invention showed that concentrations of the free insulin receptor ?-subunit in the blood of diabetes or cancer patients are significantly high. Free insulin receptor ?-subunit in blood is useful as a marker for diabetes or cancer.
    Type: Application
    Filed: April 30, 2010
    Publication date: January 20, 2011
    Applicant: Medical and Biological Laboratories Co., Ltd.
    Inventors: Yousuke Ebina, Toshiyuki Obata, Eiji Okamoto
  • Patent number: 7732154
    Abstract: Presence of free insulin receptor ?-subunit in blood was discovered. Furthermore, methods for measuring the insulin receptor ?-subunit was provided, the method comprising the steps of contacting the insulin receptor ?-subunit in a blood sample with an antibody recognizing the insulin receptor ?-subunit, and detecting the binding between the two. Measurement of the free insulin receptor ?-subunit in the blood is useful for evaluating risk factors for diabetes. In addition, the measurement methods of the present invention showed that concentrations of the free insulin receptor ?-subunit in the blood of diabetes or cancer patients are significantly high. Free insulin receptor ?-subunit in blood is useful as a marker for diabetes or cancer.
    Type: Grant
    Filed: April 15, 2004
    Date of Patent: June 8, 2010
    Assignee: Medical and Biological Laboratories Co., Ltd.
    Inventors: Yousuke Ebina, Toshiyuki Obata, Eiji Okamoto
  • Publication number: 20070059784
    Abstract: Presence of free insulin receptor ?-subunit in blood was discovered. Furthermore, methods for measuring the insulin receptor ?-subunit was provided, the method comprising the steps of contacting the insulin receptor ?-subunit in a blood sample with an antibody recognizing the insulin receptor ?-subunit, and detecting the binding between the two. Measurement of the free insulin receptor ?-subunit in the blood is useful for evaluating risk factors for diabetes. In addition, the measurement methods of the present invention showed that concentrations of the free insulin receptor ?-subunit in the blood of diabetes or cancer patients are significantly high. Free insulin receptor ?-subunit in blood is useful as a marker for diabetes or cancer.
    Type: Application
    Filed: April 15, 2004
    Publication date: March 15, 2007
    Inventors: Yousuke Ebina, Toshiyuki Obata, Eiji Okamoto
  • Patent number: 5958685
    Abstract: A mutant human insulin receptor DNA, wherein the base sequence encoding Thr.sup.831 in human insulin receptor DNA has been replaced by a base sequence encoding Ala and/or the base sequence encoding Tyr.sup.1334 therein has been replaced by a base sequence encoding Cys; a fragment of the mutant human insulin receptor DNA containing the mutation part(s); a diagnostic probe for non-insulin-dependent diabetes mellitus comprising this fragment; and a diagnostic drug for non-insulin-dependent diabetes mellitus containing this fragment.
    Type: Grant
    Filed: February 7, 1997
    Date of Patent: September 28, 1999
    Assignees: Otsuka Pharmaceutical Co. Ltd., Yousuke Ebina
    Inventor: Yousuke Ebina