Patents by Inventor Yousuke Isobe

Yousuke Isobe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8853437
    Abstract: An object of the present invention is to provide a compound having a novel structure for overcoming the defects of conventional steroid agents and NSAIDs. It is found that the particular dihydroxy bodies of eicosapentaenoic acid and docosahexaenoic acid, which have not conventionally been known (11,18-dihydroxy eicosapentaenoic acid (11,18-diHEPE), 17,18-dihydroxy eicosapentaenoic acid (17,18-diHEPE) etc.), have activity of inhibiting neutrophil, thereby solving the object. The present invention unexpectedly remarkably inhibits infiltration into a tissue of, and activation of neutrophil found out at acute inflammation. The compound of the present invention is a compound which has not conventionally been known. Therefore, utility as a new therapeutic is provided.
    Type: Grant
    Filed: February 19, 2010
    Date of Patent: October 7, 2014
    Assignee: The University of Tokyo
    Inventors: Makoto Arita, Hiroyuki Arai, Yousuke Isobe, Ryo Taguchi
  • Patent number: 8586529
    Abstract: A method for improving blood HDL/LDL cholesterol ratio, reducing blood triglyceride level, reducing blood sugar level, and/or reducing body weight, that includes ingesting a composition containing a concentrated soybean germ product. The soybean germ product includes soybean germ protein; 1.0% by weight or less of saponin relative to the total weight of the soybean germ product; and 0.5% by weight or less of isoflavone relative to the total weight of the soybean germ product.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: November 19, 2013
    Assignee: J-Oil Mills, Inc.
    Inventors: Sanshirou Saito, Toshiro Sato, Syuichi Kamo, Yousuke Isobe
  • Publication number: 20120059061
    Abstract: An object of the present invention is to provide a compound having a novel structure for overcoming the defects of conventional steroid agents and NSAIDs. It is found that the particular dihydroxy bodies of eicosapentaenoic acid and docosahexaenoic acid, which have not conventionally been known (11,18-dihydroxy eicosapentaenoic acid (11,18-diHEPE), 17,18-dihydroxy eicosapentaenoic acid (17,18-diHEPE) etc.), have activity of inhibiting neutrophil, thereby solving the object. The present invention unexpectedly remarkably inhibits infiltration into a tissue of, and activation of neutrophil found out at acute inflammation. The compound of the present invention is a compound which has not conventionally been known. Therefore, utility as a new therapeutic is provided.
    Type: Application
    Filed: February 19, 2010
    Publication date: March 8, 2012
    Applicant: The University of Tokyo
    Inventors: Makoto Arita, Hiroyuki Arai, Yousuke Isobe, Ryo Taguchi
  • Publication number: 20090186145
    Abstract: The present invention is intended to provide a composition for preventing or improving metabolic syndrome, which is safe and efficiently ingestible. Provided is a composition for reducing blood cholesterol level, improving blood HDL/LDL cholesterol ratio, reducing blood triglyceride level, reducing blood sugar level, controlling increase in liver weight, and/or reducing body weight, the composition containing soybean germ protein as an active ingredient. The composition according to the present invention improves blood cholesterol level, triglyceride, and glucose levels thereby contributing to health promotion.
    Type: Application
    Filed: June 19, 2007
    Publication date: July 23, 2009
    Applicant: J-OIL MILLS, INC.
    Inventors: Sanshirou Saito, Toshiro Sato, Syuichi Kamo, Yousuke Isobe