Patents by Inventor Yousuke MUTAI

Yousuke MUTAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazole derivative or pharmaceutically acceptable salt thereof
    Patent number: 10287251
    Abstract: The present invention is to provide a novel pyrazole derivative, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the same, and a pharmaceutical use thereof. The present invention provides a compound represented by the formula (I) or a pharmaceutically acceptable salt thereof, which has TRPM8 inhibitory effects: wherein ring A is C6-10 aryl or the like; X is CR4a or the like; R1 and R2 are a hydrogen atom or the like; R3 is a hydrogen atom or the like; R4 is a hydrogen atom or the like; ring B is C6-10 aryl or the like; R5 is a hydrogen atom or the like; R6a is a hydrogen atom or the like; R7a is a hydrogen atom or the like; R7b is a hydrogen atom or the like; R6b is a hydrogen atom or the like; R8 is a hydrogen atom or the like; n is 0, 1 or 2.
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: May 14, 2019
    Assignee: KISSEI PHARMACEUTICAL CO., LTD.
    Inventors: Hideaki Hirasawa, Fumiya Tanada, Yousuke Mutai, Nobuhiko Fushimi, Junichi Kobayashi, Yoshiro Kijima
  • PYRAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
    Publication number: 20180170879
    Abstract: [Problem] The present invention is to provide a novel pyrazole derivative, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the same, and a pharmaceutical use thereof. [Solution] The present invention provides a compound represented by the formula (I) or a pharmaceutically acceptable salt thereof, which has TRPM8 inhibitory effects: wherein ring A is C6-10 aryl or the like; X is CR4a or the like; R1 and R2 are a hydrogen atom or the like; R3 is a hydrogen atom or the like; R4 is a hydrogen atom or the like; ring B is C6-10 aryl or the like; R5 is a hydrogen atom or the like; R6a is a hydrogen atom or the like; R7a is a hydrogen atom or the like; R7b is a hydrogen atom or the like; R6b is a hydrogen atom or the like; R8 is a hydrogen atom or the like; n is 0, 1 or 2.
    Type: Application
    Filed: June 22, 2016
    Publication date: June 21, 2018
    Applicant: KISSEI PHARMACEUTICAL CO., LTD.
    Inventors: Hideaki HIRASAWA, Fumiya TANADA, Yousuke MUTAI, Nobuhiko FUSHIMI, Junichi KOBAYASHI, Yoshiro KIJIMA