Patents by Inventor Youtong WU

Youtong WU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • QUINOLINE cGAS ANTAGONIST COMPOUNDS
    Publication number: 20240092760
    Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.
    Type: Application
    Filed: June 13, 2023
    Publication date: March 21, 2024
    Inventors: Jian QIU, Qi WEI, Matt TSCHANTZ, Heping SHI, Youtong WU, Huiling TAN, Lijun SUN, Chuo CHEN, Zhijian CHEN
  • Quinoline cGAS antagonist compounds
    Patent number: 11873291
    Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.
    Type: Grant
    Filed: September 3, 2021
    Date of Patent: January 16, 2024
    Assignees: IMMUNESENSOR THERAPEUTICS, INC., THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Jian Qiu, Qi Wei, Matt Tschantz, Heping Shi, Youtong Wu, Hulling Tan, Lijun Sun, Chuo Chen, Zhijian Chen
  • QUINOLINE cGAS ANTAGONIST COMPOUNDS
    Publication number: 20240002346
    Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.
    Type: Application
    Filed: March 2, 2023
    Publication date: January 4, 2024
    Inventors: Qi WEI, Heping SHI, Matt TSCHANTZ, Jian QIU, Youtong WU, Huiling TAN, Lijun SUN, Chuo CHEN, Zhijian CHEN
  • QUINOLINE cGAS ANTAGONIST COMPOUNDS
    Publication number: 20230357158
    Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.
    Type: Application
    Filed: July 17, 2023
    Publication date: November 9, 2023
    Inventors: Qi WEI, Heping SHI, Matt TSCHANTZ, Jian QIU, Youtong WU, Huiling TAN, Lijun SUN, Chuo CHEN, Zhijian CHEN
  • STING AGONIST COMBINATION TREATMENTS WITH CYTOKINES
    Publication number: 20230121320
    Abstract: The disclosure provides, among other things, methods and uses for treating a disease or disorder, particularly tumors of a cancer patient, comprising conjointly administering effective amounts of a STING agonist, a cytokine, and an optional immune checkpoint inhibitor to the patient, wherein the STING agonist or the cytokine is intratumorally administered to the patient.
    Type: Application
    Filed: July 25, 2022
    Publication date: April 20, 2023
    Inventors: Zhijian CHEN, Lijun SUN, Youtong WU, Huiling TAN
  • QUINOLINE cGAS ANTAGONIST COMPOUNDS
    Publication number: 20230081291
    Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.
    Type: Application
    Filed: September 3, 2021
    Publication date: March 16, 2023
    Applicants: ImmuneSensor Therapeutics, Inc., The Board of Regents of the University of Texas System
    Inventors: Jian QIU, Qi WEI, Matt TSCHANTZ, Heping SHI, Youtong WU, Huiling TAN, Lijun SUN, Chuo CHEN, Zhijian CHEN
  • ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY
    Publication number: 20220105198
    Abstract: The present disclosure relates to, among other things, antibody-drug conjugates comprising a STING agonist cyclic di-nucleotide conjugated to an antibody, preparation methods therefor, and uses therefor.
    Type: Application
    Filed: December 16, 2021
    Publication date: April 7, 2022
    Inventors: Zhijian CHEN, Heping SHI, Qi WEI, Chuo CHEN, Lijun SUN, Jian QIU, Youtong WU
  • Antibody-sting agonist conjugates and their use in immunotherapy
    Patent number: 11213592
    Abstract: The present disclosure relates to, among other things, antibody-drug conjugates comprising a STING agonist cyclic di-nucleotide conjugated to an antibody, preparation methods therefor, and uses therefor.
    Type: Grant
    Filed: May 11, 2021
    Date of Patent: January 4, 2022
    Assignees: IMMUNESENSOR THERAPEUTICS, INC., THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Zhijian Chen, Heping Shi, Qi Wei, Chuo Chen, Lijun Sun, Jian Qiu, Youtong Wu
  • ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY
    Publication number: 20210290774
    Abstract: The present disclosure relates to, among other things, antibody-drug conjugates comprising a STING agonist cyclic di-nucleotide conjugated to an antibody, preparation methods therefor, and uses therefor.
    Type: Application
    Filed: May 11, 2021
    Publication date: September 23, 2021
    Applicants: ImmuneSensor Therapeutics, Inc., The Board of Regents of the University of Texas System
    Inventors: Zhijian CHEN, Heping SHI, Qi WEI, Chuo CHEN, Lijun SUN, Jian QIU, Youtong WU
  • Antibody-STING agonist conjugates and their use in immunotherapy
    Patent number: 11033635
    Abstract: The present disclosure relates to, among other things, antibody-drug conjugates comprising a STING agonist cyclic di-nucleotide conjugated to an antibody, preparation methods therefor, and uses therefor.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: June 15, 2021
    Assignees: ImmuneSensor Therapeutics, Inc., The Board of Regents of the University of Texas System
    Inventors: Zhijian Chen, Heping Shi, Qi Wei, Chuo Chen, Lijun Sun, Jian Qiu, Youtong Wu
  • ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY
    Publication number: 20210015941
    Abstract: The present disclosure relates to, among other things, antibody-drug conjugates comprising a STING agonist cyclic di-nucleotide conjugated to an antibody, preparation methods therefor, and uses therefor.
    Type: Application
    Filed: July 20, 2020
    Publication date: January 21, 2021
    Applicants: ImmuneSensor Therapeutics, Inc., The Board of Regents of the University of Texas System
    Inventors: Zhijian CHEN, Heping SHI, Qi WEI, Chuo CHEN, Lijun SUN, Jian QIU, Youtong WU