Patents by Inventor Youxi CHEN

Youxi CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrolide derivatives, preparation method and application thereof
    Patent number: 12410191
    Abstract: Provided are a macrolide derivative represented by formula (I), a preparation method thereof, and an application of the macrolide derivative as an inhibitor of one or more protein kinases of TRK, ALK and ROS1,
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: September 9, 2025
    Assignees: Zhejiang Hisun Pharmaceutical Co., Ltd., Shanghai Aryl Pharmtech Co., Ltd
    Inventors: Youxi Chen, Liang Gong, Xingwu Zhu, Qing Xiang, Wentao Mao, Cheng Ye, Taishan Hu, Lei Chen, Guoping Jiang
  • AROMATIC ACETYLENE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20240382465
    Abstract: Disclosed in the present invention are an aromatic acetylene derivative, a preparation method therefor, a pharmaceutical composition containing the derivative, and the use of the aromatic acetylene derivative or the pharmaceutical composition thereof in medicines. Specifically, disclosed in the present invention are an aromatic acetylene derivative as represented by general formula (A-I), a preparation method therefor and a pharmaceutically acceptable salt thereof, and the use thereof as a therapeutic agent, particularly an LPXC inhibitor, wherein the definition of each substituent in the general formula (A-I) is the same as that in the description.
    Type: Application
    Filed: August 4, 2022
    Publication date: November 21, 2024
    Applicants: ZHEJIANG HISUN PHARMACEUTICAL CO., LTD., SHANGHAI ARYL PHARMTECH CO., LTD.
    Inventors: Yanghui GUO, Lichen MENG, Weiwei LIAO, Heng ZHANG, Chengfei WU, Youxi CHEN, Cheng YE, Wenjian QIAN, Lei CHEN, Enguo WU
  • TETRACYCLIC DERIVATIVE, METHOD FOR PREPARING SAME AND USE THEREOF IN MEDICINE
    Publication number: 20230295163
    Abstract: The present invention relates to a tetracyclic derivative, a method for preparing same and the use thereof in medicine. In particular, the present invention relates to a tetracyclic derivative represented by general formula (I), a method for preparing same and a pharmaceutically acceptable salt thereof, and the use thereof as a therapeutic agent, especially as a K-Ras GTPase inhibitor, with definitions of each substituent in general formula (I) being the same as of which are defined in the description.
    Type: Application
    Filed: August 19, 2021
    Publication date: September 21, 2023
    Applicants: ZHEJIANG HISUN PHARMACEUTICAL CO., LTD., SHANGHAI ARYL PHARMTECH CO., LTD.
    Inventors: Youxi CHEN, Chaoying CHENG, Liang GONG, Wentao MAO, Qing XIANG, Weifeng ZHAO, Wenwen ZHAO, Yanling HE, Mingjiang ZHU, Cheng YE, Taishan HU, Wenjian QIAN, Lei CHEN
  • MACROLIDE DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF
    Publication number: 20220235070
    Abstract: Provided are a macrolide derivative represented by formula (I), a preparation method thereof, and an application of the macrolide derivative as an inhibitor of one or more protein kinases of TRK, ALK and ROS1,
    Type: Application
    Filed: May 20, 2020
    Publication date: July 28, 2022
    Inventors: Youxi CHEN, Liang GONG, Xingwu ZHU, Qing XIANG, Wentao MAO, Cheng YE, Taishan HU, Lei CHEN, Guoping JIANG