Abstract: The present invention belongs to the field of medicinal chemistry, and particularly relates to a pleuromutilin derivative with a thiazole side chain and preparation and application. The pleuromutilin derivative with the thiazole side chain is a compound of formula 2 or a pharmaceutically acceptable salt thereof, and a solvent compound, enantiomer, diastereoisomer, tautomer, or mixture of any proportion of the compound of formula 2 or the pharmaceutically acceptable salt thereof, comprising racemic mixtures: The pleuromutilin derivative has good antibacterial activity, is particularly suitable for use as a novel antibacterial drug for animal or human systemic infection, and has good water solubility.

Abstract: The present disclosure provides a perspective switching method and apparatus, an electronic device, a storage medium, and a program product. The method includes: during a process of playing a current first video stream, in response to a first trigger operation, displaying a perspective navigation window and playing a second video stream in the perspective navigation window, in which navigation video frames in the second video stream are obtained by extracting video frames from different first video streams, and corresponding playback progress of different navigation video frames in respective first video streams is different; and in response to a second trigger operation, taking a target first video stream as a current first video stream and playing the current first video stream, in which the target first video stream is a first video stream having a same perspective as a current navigation video frame displayed in the perspective navigation window.

Abstract: Provided are a view angle switching method, apparatus and system for a free view angle video, a device, and a medium. The method is applied to a client and includes: determining view angle switching information according to a view angle switching operation triggered by a user, transmitting the view angle switching information to a low-latency room corresponding to the client through a low-latency server so that in response to determining that a view angle change message in the low-latency room is monitored, a media server determines a target video stream after a view angle is switched based on the view angle switching information and pushes the target video stream to the low-latency room; and obtaining and playing the target video stream in the low-latency room through the low-latency server.

Abstract: Embodiments of the present disclosure provide a livestreaming audio processing method and device, and the method includes: a processor of a first terminal receives second audio data sent by a second terminal; an audio processing apparatus of the first terminal receives the second audio data and third audio data sent by the processor through different channels, where the third audio data is audio data in the first terminal; the audio processing apparatus plays the second audio data; the audio processing apparatus sends first audio data recorded and the third audio data to the processor; and the processor sends the first audio data and the third audio data to the second terminal.