Abstract: The present invention provides a cosmetic shaped product: which is substantially formed with relatively low-molecular-weight hyaluronic acid or a water-soluble salt thereof having a high penetrability into the skin; which is easily soluble to water; and which has satisfactory handling properties, and a method for producing the cosmetic shaped product. There is provided a cosmetic shaped product being a sponge-like shaped body formed with at least one polyanionic polysaccharide of hyaluronic acid and a water-soluble salt thereof each having an average molecular weight of 30,000 or lower, the sponge-like shaped body having a bulk specific gravity of 5 to 500 mg/mL. This cosmetic shaped product can be produced by freeze-drying an aqueous solution having a content of the polyanionic polysaccharide of 0.5 to 30% by mass.

Abstract: The present invention provides a surgical drape such that even when it is incised or punctured with a surgical tool in a state where it is pasted to an uneven surface having a low smoothness or to a part having a high curvature, such as a hand, a leg, or the head, a part subjected to incision or the like and its surroundings are unlikely to peel off, the surgical drape having excellent handling properties and safety. The surgical drape is a surgical drape 10 provided with a tacky layer 5 to be incised or punctured with a surgical tool, the tacky layer 5 having a tacky surface 2 to be brought into contact with a region including a surgery site of a living body. The surgical drape 10 has a Young's modulus of 10.0 MPa or less and may further be provided with a film-like base material 15 disposed by lamination on a surface on an opposite side of the tacky surface 2 of the tacky layer 5.

Abstract: The present invention provides a cosmetic shaped product: which is substantially formed with relatively low-molecular-weight hyaluronic acid or a water-soluble salt thereof having a high penetrability into the skin; which is easily soluble to water; and which has satisfactory handling properties, and a method for producing the cosmetic shaped product. There is provided a cosmetic shaped product being a sponge-like shaped body formed with at least one polyanionic polysaccharide of hyaluronic acid and a water-soluble salt thereof each having an average molecular weight of 30,000 or lower, the sponge-like shaped body having a bulk specific gravity of 5 to 500 mg/mL. This cosmetic shaped product can be produced by freeze-drying an aqueous solution having a content of the polyanionic polysaccharide of 0.5 to 30% by mass.

Abstract: There are provided: a preservative composition and a preservation liquid which can improve the shelf life of fruit and vegetables and which are safer to the human body; and fruit and vegetables treated with the preservation liquid. The present invention relates to a preservative composition for fruit and vegetables, the preservative composition containing an organic acid and/or a salt thereof, and at least one selected from the group consisting of glucosamine, glucosamine derivatives, chitin oligosaccharides, chitosan oligosaccharides, and salts thereof. Moreover, the present invention relates to a preservation liquid for fruit and vegetables, the preservation liquid containing the preservative composition and a liquid medium. Further, the present invention relates to fruit and vegetables treated with the preservation liquid.

Abstract: Provided is a pharmaceutical composition, including a drug and a collagen, in which the composition is satisfactory in handleability and has sustained-release property. The sustained-release pharmaceutical composition includes: a drug; a collagen; and at least one kind of sugar selected from monosaccharides, disaccharides, trisaccharides, and tetrasaccharides. The inventors of the present invention have found that the in vivo administration of a collagen solution containing a sugar results in the gelation of a collagen. Based on this finding, the inventors have found that a composition containing a drug, a collagen, and a sugar can control the release rate of the drug, and such composition can be used as a sustained-release pharmaceutical composition.

Abstract: Means for transferring efficiently a desired nucleic acid into a cell is provided. The present invention comprises using a complex comprising a collagen or a collagen derivative, and a desired nucleic acid.

Abstract: Provided is a pharmaceutical composition, including a drug and a collagen, in which the composition is satisfactory in handleability and has sustained-release property. The sustained-release pharmaceutical composition includes: a drug; a collagen; and at least one kind of sugar selected from monosaccharides, disaccharides, trisaccharides, and tetrasaccharides. The inventors of the present invention have found that the in vivo administration of a collagen solution containing a sugar results in the gelation of a collagen. Based on this finding, the inventors have found that a composition containing a drug, a collagen, and a sugar can control the release rate of the drug, and such composition can be used as a sustained-release pharmaceutical composition.

Abstract: A cell cultivation carrier implantable in vivo having independent pore with opening of 100 ?m-1000 ?m on the surface thereof produced by neutralization•gellation of collagen acidic solution, said collagen acidic solution is preliminary prepared by passing through a filter of 10 ?m or less pore size by 5-20 mg/mL concentration. Especially, a cell cultivation carrier implantable in vivo having sufficiently self-organized accumulation shape•structure obtained by carrying out said neutralization under directionally supplying of alkali.

Abstract: Means for transferring efficiently a desired nucleic acid into a cell is provided. The present invention comprises using a complex comprising a collagen or a collagen derivative, and a desired nucleic acid.

Abstract: A cell cultivation carrier implantable in vivo having independent pore with opening of 100 ?m-1000 ?m on the surface thereof produced by neutralization•gellation of collagen acidic solution, said collagen acidic solution is preliminary prepared by passing through a filter of 10 ?m or less pore size by 5-20 mg/mL concentration. Especially, a cell cultivation carrier implantable in vivo having sufficiently self-organized accumulation shape•structure obtained by carrying out said neutralization under directionally supplying of alkali.

Abstract: Means for transferring efficiently a desired nucleic acid into a cell is provided.