Patents by Inventor Yu Chang
Yu Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260157633Abstract: A wearable monitoring device for soft-tissue Young's modulus includes a pressure application mechanism, a contact radius sensor, a contact force sensor, and a wearable mechanism. The pressure application mechanism includes an indenter with a hemispherical contact surface. The contact radius sensor includes a flexible pressure sensing array disposed on the contact surface and configured to detect a pressure distribution along a height direction of the indenter. The contact radius sensor is configured to output a first electrical signal in response to a contact pressure when the contact surface contacts a measured soft tissue. The contact force sensor is disposed on the pressure application mechanism and configured to output a second electrical signal in response to the contact pressure provided by the pressure application mechanism when the contact surface contacts the measured soft tissue. The monitoring device can achieve accurate, continuous, and dynamic monitoring of the Young's modulus of soft tissues.Type: ApplicationFiled: August 14, 2025Publication date: June 11, 2026Applicants: Suzhou Institute for Advanced Research, University of Science and Technology of China, University of Science and Technology of ChinaInventors: Tingrui PAN, Huizhi WANG, Yu CHANG, Zhenning WANG
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Publication number: 20260157634Abstract: A wearable device for monitoring soft-tissue Young's modulus includes: a pressure application mechanism, a contact radius sensor, a contact force sensor, and a wearable mechanism, where the wearable mechanism includes a housing and a strap; the pressure application mechanism includes an indenter disposed inside the housing; the contact radius sensor includes at least two flexible pressure sensing arrays; each flexible pressure sensing array includes a plurality of sensing units configured to detect a pressure distribution along a height direction of the indenter; the contact force sensor is disposed on the pressure application mechanism and contacts an inner surface of the housing; the contact radius sensor is configured to output a first electrical signal in response to a contact pressure when the contact surface contacts a measured soft tissue; and the contact force sensor is configured to output a second electrical signal in response to the contact pressure.Type: ApplicationFiled: August 14, 2025Publication date: June 11, 2026Applicants: Suzhou Institute for Advanced Research, University of Science and Technology of China, University of Science and Technology of ChinaInventors: Tingrui PAN, Huizhi WANG, Yu CHANG, Zhenning WANG
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Publication number: 20260138289Abstract: The present invention discloses an irreversible passive gripping apparatus and method. The apparatus includes: a fixed assembly, an accommodating space, a sliding assembly, a connecting rod assembly, and a clamping assembly. When the sliding assembly slides toward the clamping assembly, the clamping assembly rotates out of the interior of the accommodating space to form a clamping angle. The present invention realizes stable passive gripping and automatic locking without power input, ensures safe and reliable operation, and adapts to the tolerances of different bucket edges.Type: ApplicationFiled: December 31, 2024Publication date: May 21, 2026Inventors: Yu CHANG, Hao FAN, Francisco Bernal Martínez, Wei WANG, Jingqian LIU, Xiangbao ZENG, Tianxin AN, Xiangjun ZU, Miguel Angel Bautista García, José Antonio Cuberos Castaño, Álvaro Jesús Cuadrado Álvaro, Ya ZHOU, Yun HE, Zhou ZHOU, Shuaizhen WU, Kunlin MU, Hexin SUN
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Publication number: 20260133841Abstract: Approaches presented herein provide for the reduction of workload bottlenecks during processing by offloading workload data to available data processing unit (DPU) memory, such as from graphics processing unit (GPU) memory or central processing unit (CPU) memory. Interfaces may be used to store the workload data to the pool of DPU memory, such as double data rate (DDR) memory, on-board non-volatile memory express (NVMe) devices, or NVMe devices over fabric. Interfaces may also be used to retrieve identified workload data required to complete a workload. The retrieved workload data may be provided to the GPU where the workload is completed. The pool of DPU memory may orchestrate transfers of the workload data. The workload data may be offloaded to the pool of DPU memory for training of a machine learning model. The workload data offloaded to the pool of DPU memory for training of a machine learning model may include model states, activation functions, or model checkpoints.Type: ApplicationFiled: November 12, 2024Publication date: May 14, 2026Inventors: Manjunath Gorentla Venkata, Rohit Zambre, Yu Chang, Sreeram Potluri
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Patent number: 12551579Abstract: A F-18 positron diagnostic contrast agent precursor, the F-18 positron diagnostic contrast agent prepared using the F-18 positron diagnostic contrast agent precursor can be used for positron emission tomography to detect type II vesicular monoamine transporter, produce no metabolites similar to F-18-propanol because the F-18 is marked on the aromatic ring, and can reduce the background value of normal organs while using.Type: GrantFiled: September 29, 2022Date of Patent: February 17, 2026Assignee: INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUANInventor: Yu Chang
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Publication number: 20260024673Abstract: Disclosed are a remote-controlled dismantling robot and dismantling method for nuclear facility decommissioning, relating to the technical field of nuclear facility decommissioning. The robot includes a tracked chassis, a hydraulic arm, a hydraulic system, and a quick change mechanism for hydraulic tool head, where the tracked chassis includes a vehicle chassis, a rotating mechanism, track systems, and support leg systems; and the hydraulic arm includes a multi-stage hinged arm and arm oil cylinder. The robot can dismantle to-be-decommissioned nuclear facilities under human remote control, which can decrease the radiation dose to the operators.Type: ApplicationFiled: November 4, 2024Publication date: January 22, 2026Inventors: Guoqiang SHAO, Yu CHANG, Tianxin AN, Qizhao MA, Hao FAN, Kunlin MU, Chao YANG, Bo DENG, Jianqiang WANG, Zhouyang JIANG, Kun GONG, Ping BAI
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Publication number: 20250343570Abstract: Circuits for reflection cancellation in single-ended signaling are disclosed. A transmission circuit includes a control circuit configured to receive a plurality of input signals that include a plurality of symbols having at least one bit and a data driver circuit configured to generate a particular signal on a transmission medium using a particular symbol of the plurality of symbols. The transmission circuit further includes a reflection cancellation circuit configured to, after a generation of the particular signal, generate a reflection cancellation signal on the transmission medium using an inverted value of a different symbol of the plurality of symbols received prior to the particular symbol. A first composite of the particular signal and the cancellation signal is readable at a load as a value of the particular symbol, wherein the load is configured to receive a transmitted signal via the transmission medium.Type: ApplicationFiled: July 10, 2025Publication date: November 6, 2025Inventors: Yu Chang, Mitesh D. Katakwar, Huabo Chen, Huy M. Nguyen
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Patent number: 12388487Abstract: Circuits for reflection cancellation in single-ended signaling are disclosed. A transmission circuit includes a control circuit configured to receive a plurality of input signals that include a plurality of symbols having at least one bit and a data driver circuit configured to generate a particular signal on a transmission medium using a particular symbol of the plurality of symbols. The transmission circuit further includes a reflection cancellation circuit configured to, after a generation of the particular signal, generate a reflection cancellation signal on the transmission medium using an inverted value of a different symbol of the plurality of symbols received prior to the particular symbol. A first composite of the particular signal and the cancellation signal is readable at a load as a value of the particular symbol, wherein the load is configured to receive a transmitted signal via the transmission medium.Type: GrantFiled: November 21, 2023Date of Patent: August 12, 2025Assignee: Apple Inc.Inventors: Yu Chang, Mitesh D. Katakwar, Huabo Chen, Huy M. Nguyen
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Publication number: 20250100994Abstract: The present invention relates to a method for preparing a class of novel CDK12/13 covalent inhibitors or a pharmaceutical composition thereof, and use thereof. The class of novel CDK12/13 covalent inhibitors of the present invention have a structure shown in formula (I). Such compounds can serve as protein kinase inhibitors, can effectively and highly selectively inhibit the CDK12/13 protein kinase activity, and can inhibit the proliferation, migration, and invasion of various tumor cells.Type: ApplicationFiled: September 27, 2024Publication date: March 27, 2025Inventors: Arul M. Chinnaiyan, George X. Wang, Yu Chang, Jean Tien, Ke Ding, Jianzhang Yang, Weixue Huang, Zhen Wang
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Publication number: 20250105870Abstract: Circuits for reflection cancellation in single-ended signaling are disclosed. A transmission circuit includes a control circuit configured to receive a plurality of input signals that include a plurality of symbols having at least one bit and a data driver circuit configured to generate a particular signal on a transmission medium using a particular symbol of the plurality of symbols. The transmission circuit further includes a reflection cancellation circuit configured to, after a generation of the particular signal, generate a reflection cancellation signal on the transmission medium using an inverted value of a different symbol of the plurality of symbols received prior to the particular symbol. A first composite of the particular signal and the cancellation signal is readable at a load as a value of the particular symbol, wherein the load is configured to receive a transmitted signal via the transmission medium.Type: ApplicationFiled: November 21, 2023Publication date: March 27, 2025Inventors: Yu Chang, Mitesh D. Katakwar, Huabo Chen, Huy M. Nguyen
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Publication number: 20240312083Abstract: A map display method, apparatus, a storage medium, and an electronic apparatus are provided. The method includes determining a touch coordinate of a touch point of a touch action on a target map in a case that the touch action on the target map displayed on a touch display screen is detected; determining a rectangular area centered on the touch coordinate according to the touch coordinate, a first preset length, and a second preset length; and displaying an image included in the rectangular area in a target display area on the touch display screen.Type: ApplicationFiled: May 23, 2024Publication date: September 19, 2024Applicant: DREAME INNOVATION TECHNOLOGY (SUZHOU) CO., LTD.Inventors: Yong ZOU, Yu CHANG, Yi QI
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Patent number: 12031776Abstract: Disclosed are an unblocking apparatus for a furnace discharging pipe and a use method. The unblocking apparatus includes a rail, a rail car that may move along the rail, an unblocking drive mechanism arranged on the rail car, a heat-unblocking component, a cold-unblocking component, and a material receiving component that is used to receive a blocking material in the discharging pipe, and a drive end of the unblocking drive mechanism is detachably connected with one end of the heat-unblocking component and the cold-unblocking component respectively. The present application effectively handles different blockage situations of the furnace discharging pipe by connecting the unblocking drive mechanism with an unblocking rod capable of heat-unblocking and a drilling rod capable of cold-unblocking, thereby two modes of heat-unblocking and cold-unblocking are performed on the furnace discharging pipe; and the discharging pipe may be unblocked by a remote operation.Type: GrantFiled: October 23, 2023Date of Patent: July 9, 2024Assignees: China Nuclear Sichuan Environmental Protection Engineering Co., Ltd., China Building Materials Academy, China Nuclear Power Engineering Co., Ltd.Inventors: Weidong Xu, Yu Chang, Yongchang Zhu, Hong Duan, Chunyu Tian, Wei Wu, Debo Yang, Qingbin Zhao, Shuaizhen Wu, Lin Wang, Zhu Cui, Heyi Guo, Maosong Fan, Yuancheng Sun, Jie Mei, Xiaoli An, Yongxiang Zhao, Qinda Liu
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Publication number: 20240142175Abstract: Disclosed are an unblocking apparatus for a furnace discharging pipe and a use method. The unblocking apparatus includes a rail, a rail car that may move along the rail, an unblocking drive mechanism arranged on the rail car, a heat-unblocking component, a cold-unblocking component, and a material receiving component that is used to receive a blocking material in the discharging pipe, and a drive end of the unblocking drive mechanism is detachably connected with one end of the heat-unblocking component and the cold-unblocking component respectively. The present application effectively handles different blockage situations of the furnace discharging pipe by connecting the unblocking drive mechanism with an unblocking rod capable of heat-unblocking and a drilling rod capable of cold-unblocking, thereby two modes of heat-unblocking and cold-unblocking are performed on the furnace discharging pipe; and the discharging pipe may be unblocked by a remote operation.Type: ApplicationFiled: October 23, 2023Publication date: May 2, 2024Applicants: China Nuclear Sichuan Environmental Protection Engineering Co., Ltd., China Building Materials Academy, China Nuclear Power Engineering Co., Ltd.Inventors: Weidong XU, Yu CHANG, Yongchang ZHU, Hong DUAN, Chunyu TIAN, Wei WU, Debo YANG, Qingbin ZHAO, Shuaizhen WU, Lin WANG, Zhu CUI, Heyi GUO, Maosong FAN, Yuancheng SUN, Jie MEI, Xiaoli AN, Yongxiang ZHAO, Qinda LIU
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Publication number: 20240123096Abstract: A F-18 positron diagnostic contrast agent precursor, the F-18 positron diagnostic contrast agent prepared using the F-18 positron diagnostic contrast agent precursor can be used for positron emission tomography to detect type II vesicular monoamine transporter, produce no metabolites similar to F-18-propanol because the F-18 is marked on the aromatic ring, and can reduce the background value of normal organs while using.Type: ApplicationFiled: September 29, 2022Publication date: April 18, 2024Applicant: INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUANInventor: Yu CHANG
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Publication number: 20240024518Abstract: The present invention provides a contrast agent which is efficiently and specifically absorbed by tumor cells, suitable for use in single photon emission computed tomography for the diagnosis, efficacy assessment and tumor tracking of neuroblastoma, pheochromocytoma or congestive heart failure.Type: ApplicationFiled: January 19, 2023Publication date: January 25, 2024Applicant: INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUANInventors: Shiu-Wen LIU, Yi-Jhih CHEN, Wei-Hsi CHEN, Yu CHANG, Cheng-Fang HSU
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Publication number: 20230228757Abstract: The invention relates to a method for judging risk of suffering kidney cancer. The method includes detecting a PSMB9 protein concentration value from a test sample. And a risk factor value is obtained after processing the PSMB9 protein concentration value with an age. When the score of the risk factor value is greater than a defined threshold value of the risk factor threshold value, then the test sample is classified as a high risk sample of a of potential kidney cancer patient.Type: ApplicationFiled: July 5, 2022Publication date: July 20, 2023Inventors: YI-TING CHEN, RONG-SHING CHANG, YU CHANG, CHIEN-LUN CHEN, KAI-JIE YU, YING-HSU CHANG
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Patent number: 11674173Abstract: An operation method of a multiplex slide plate device is provided. First, the multiplex slide plate device is assembled, including a slide plate, a sacrificial layer and a housing. The slide plate has reaction vessels, and the sacrificial layer has a microfluidic channel composed of an injection channel, a main channel and a distal channel. A sample solution is injected to the injection channel, such that the sample solution flows from the injection channel through the main channel to the distal channel, wherein the sample solution loads into the reaction vessels. Afterwards, an oil is injected to the injection channel, such that the oil flows from the injection channel through the main channel to the distal channel, wherein the oil removes the sample solution not loaded into the reaction vessels. Next, the sacrificial layer is heated to melt, and the melted sacrificial layer is mixed with the oil.Type: GrantFiled: March 26, 2021Date of Patent: June 13, 2023Assignee: Quark Biosciences Taiwan, Inc.Inventors: Chung-Fan Chiou, Cheng-Wey Wei, Yu Chang, Ming-Chuan Hsu
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Patent number: 11598003Abstract: Apparatus for processing a substrate are provided herein. In some embodiments a showerhead assembly includes a gas distribution plate having a plurality of apertures; a holder having a wall, an radially inwardly extending flange extending from a lower portion of the wall and coupled to the gas distribution plate, and a radially outwardly extending flange extending from an upper portion of the wall, wherein the wall has a thickness between about 0.015 inches and about 0.2 inches; and a heating apparatus disposed above and spaced apart from the gas distribution plate, wherein the heating apparatus includes a heater configured to heat the gas distribution plate.Type: GrantFiled: September 12, 2017Date of Patent: March 7, 2023Assignee: APPLIED MATERIALS, INC.Inventors: Faruk Gungor, Dien-Yeh Wu, Joel M. Huston, Mei Chang, Xiaoxiong Yuan, Kazuya Daito, Avgerinos V. Gelatos, Takashi Kuratomi, Yu Chang, Bin Cao
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Patent number: 11495932Abstract: Embodiments of a slip ring for use in a rotatable substrate support are provided herein. In some embodiments a slip ring includes a main body having a top wall, a bottom wall, and a sidewall extending between the top and bottom walls, wherein the top wall, bottom wall, and sidewall define an inner volume within the main body, wherein a central opening is formed through the top wall; a plurality of annular containers disposed within the inner volume and coaxially with the main body, wherein the plurality of annular containers are vertically spaced apart from one another, and wherein each of the plurality of annular containers contains a first volume of an electrically conductive liquid; an upper cylindrical body rotatably disposed in the central opening; a lower cylindrical body fixedly coupled to the lower wall of the main body.Type: GrantFiled: June 6, 2018Date of Patent: November 8, 2022Assignee: APPLIED MATERIALS, INC.Inventors: Muhannad Mustafa, Yu Chang, William Kuang, Muhammad M. Rasheed, Xiping Huo
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Patent number: 11466002Abstract: This invention discloses method for preparing a non-radioactive standard ?-CFT. Using cocaine hydrochloride as the starting material, and after a series of hydrolysis, dehydration, esterification and bonding reactions, a non-radioactive standard (2?-Carbomethoxy-3?-(4-fluoropenyl) tropane) is prepared. Furthermore, this preparation method has fewer steps, is easy to operate, and the purity of the product is as high as 97.97%. Therefore, the method for preparing a non-radioactive standard ?-CFT can promote the development of positron imaging in the diagnosis of Parkinson's disease.Type: GrantFiled: April 8, 2021Date of Patent: October 11, 2022Assignee: INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN, R.O.C.Inventors: Ching Yun Lee, Yu Chang