Abstract: The present invention is a data cleaning device executing a data cleaning method. The data cleaning method includes executing an application, and executing a prompt plugin management program. The operation of executing the prompt plugin management program includes generating a prompt instruction based on an unformatted content via a first prompt template, transmitting the prompt instruction to a first device, and receiving a formatted content from the first device. The formatted content is generated by the first device based on the prompt instruction through a large language model.

Abstract: The present invention provides a preparation method of pharmaceutical composition for treating chronic stroke, involving injection via brain into the cranium of a patient having chronic stroke for six months or more; the pharmaceutical composition is a suspension at least comprising adipose-derived stem cells treated by cell expansion, an active synergistic component and a growth factor, wherein the expression level of CD34 and CD45 of the adipose-derived stem cells treated by cell expansion is 10% or less, and the expression level of CD90 and CD105 is 90% or more; the active synergistic component is an extracellular vesicle; the growth factor is at least one selected from the group consisting of HGF, G-CSF, Fractalkine, IP-10, EGF, IL-1?, IL-1?, IL-4, IL-5, IL-13, IFN?, TGF? and sCD40L. The present invention overcomes the limitations of previous cell therapy and provides a cell-based preparation that is clinically safe and therapeutically effective for chronic cerebral stroke.

Abstract: The present disclosure provides a pharmaceutical composition including an adipose tissue-derived extracellular vesicle and a biologic, and a use of the pharmaceutical composition for treating arthritis. The pharmaceutical composition of the present disclosure achieves the effect of treating arthritis through various efficacy experiments.

Abstract: The present disclosure provides a method for preparing mesenchymal stem cell-derived extracellular vesicle, the mesenchymal stem cell-derived extracellular vesicle prepared by the method, and use of the mesenchymal stem cell-derived extracellular vesicle for reducing adipogenesis and treating osteoarthritis. The mesenchymal stem cell-derived extracellular vesicle of the present disclosure achieves the effect of reducing adipogenesis and treating osteoarthritis through various efficacy experiments.

Abstract: The present invention relates to a method for preparing a modified stem cell, including the following steps: a cell culture step: culturing stem cells in a first culture medium of a culture dish at a predetermined cell density, and removing the first culture medium after a first culture time to obtain a first cell intermediate; an activity stimulation step: preserving the first cell intermediate in a freezing container having a cell cryopreservation solution, and performing a constant temperature stimulation treatment or a variable temperature stimulation treatment for at least more than 1 day; and a product collection step: after completing the activity stimulation step, placing the freezing container in an environment at a thawing temperature for thawing, and then removing the cell cryopreservation solution to obtain the modified stem cell. The modified stem cell can release at least one or more of IL-4, IL-5, IL-13, G-CSF, Fractalkine, and EGF.

Abstract: The present disclosure provides a pharmaceutical composition for treating Alzheimer’s disease, which at least includes an extracellular vesicle that is prepared by a method including: a first culturing step: performing an amplification culture of an adipose-derived stem cell in a first culture medium at a cell density of 6,000-15,000 cells/cm2 until an amplification amount of the adipose-derived stem cell is above 90% of that before the culture; a second culturing step: culturing the amplified adipose-derived stem cell in a second culture medium at a cell density of 10,000-100,000 cells/cm2 for 20-30 hours; and an extracellular vesicle separating step: collecting a culture solution and separating the extracellular vesicle from the culture solution by utilizing a tangential flow filtration (TFF) or ultrafiltration method.

Abstract: The present invention provides a pharmaceutical composition for treating chronic stroke, involving injection via brain into the cranium of a patient having chronic stroke for six months or more; the pharmaceutical composition is a suspension at least comprising TS stem cells, an active synergistic component and a growth factor, wherein the expression level of CD34 and CD45 of the TS stem cells is 10% or less, and the expression level of CD90 and CD105 is 90% or more; the active synergistic component is an extracellular vesicle; the growth factor is at least one selected from the group consisting of HGF, G-CSF, Fractalkine, IP-10, EGF, IL-1?, IL-1?, IL-4, IL-5, IL-13, IFN?, TGF? and sCD40L. The present invention overcomes the limitations of previous cell therapy and provides a cell-based preparation that is clinically safe and therapeutically effective for chronic cerebral stroke.

Abstract: A tile scraper structure contains: a handle and a blade module. The handle includes a grip portion, a connection segment, an accommodation cavity, a slidable switch having a pull lever, and a positioning element which has a fixing loop and a protrusion. The connection segment has a polygonal orifice and a slot. The blade module includes a blade and a locating seat accommodated in the polygonal orifice. The locating seat has a notch configured to engage with the protrusion. The handle further includes a spring received in the accommodation cavity and abutting against the slidable switch, such that the slidable switch actuates the positioning element so that the spring urges the protrusion to engage with the notch.

Abstract: The present invention provides a new method for decreasing level of a proinflammatory cytokine in a subject, which is further able to treating cytokine release syndrome caused by CAR T-cell therapy or a disorder mediated by an overproduction of a proinflammatory cytokine. The method comprises administering to the subject in need thereof a therapeutically effective amount of a pharmaceutical composition which is comprising at least one selected from the group consisting of Phenothiazine derivatives, Graptopetalum paraguayense extract, Rhodiola rosea extract and Histone Deacetylase (HDAC) inhibitors.

Abstract: A method for protecting content of vector graphics formats is provided. A first vector graphics is scrambled to generate a second vector graphics. Then a plurality of pixel samplings are performed by the first vector graphics which generating at least a recovery information object according to a predetermined graphics. The predetermined graphics is watermarked to generate a watermark object. And the recovery information object is encoded and embedded in the watermark object to generate a recovery information watermark. Finally, the second vector graphics, the recovery information watermark, and the recovery code are combined to generate a protected first vector graphics.

Abstract: A method for protecting content of vector graphics formats is provided. A first vector graphics is scrambled to generate a second vector graphics. Then a plurality of pixel samplings are performed by the first vector graphics which generating at least a recovery information object according to a predetermined graphics. The predetermined graphics is watermarked to generate a watermark object. And the recovery information object is encoded and embedded in the watermark object to generate a recovery information watermark. Finally, the second vector graphics, the recovery information watermark, and the recovery code are combined to generate a protected first vector graphics.

Abstract: A method and system for processing multimedia data. A digital content player is first connected to a digital content server via RTSP in accordance with URL information embedded by prototype definition. Next, multimedia data is accessed and processed from the digital content server via RTSP. Finally, remote text data is retrieved via SOAP in accordance with the URL information when text data is processed.