Abstract: The invention is directed to a method to predict prognostic results for diseases including acute myeloid leukemia (AML) by analyzing novel markers which comprises microRNA/mRNA (miRNA/mRNA) pairings. In particular, the miRNA/mRNA pairings are a kind of NPM1 mutation-modulated miRNA/mRNA regulation pairs.

Abstract: A method for measuring performance parameters of an infrared focal plane array (IRFPA) module has steps of capturing continuous digital images from the IRFPA module, performing image division on each of the continuous digital images, and measuring multiple performance parameters of each divided digital image, including signal transmission function, a temporal noise equivalent temperature difference, a spatial noise equivalent temperature difference, non-uniformity and operability, thereby increasing accuracy in measuring the performance parameters of the IRFPA module. Also, a method for detecting bad pixels of an IRFPA module includes a gain value method, an offset value method, a temporal noise method and a spatial noise method, is applicable to the IRFPA module with more than two response areas, and avoids incorrect detection to treat pixels in different response areas as bad pixels.

Abstract: A method for measuring performance parameters of an infrared focal plane array (IRFPA) module has steps of capturing continuous digital images from the IRFPA module, performing image division on each of the continuous digital images, and measuring multiple performance parameters of each divided digital image, including signal transmission function, a temporal noise equivalent temperature difference, a spatial noise equivalent temperature difference, non-uniformity and operability, thereby increasing accuracy in measuring the performance parameters of the IRFPA module. Also, a method for detecting bad pixels of an IRFPA module includes a gain value method, an offset value method, a temporal noise method and a spatial noise method, is applicable to the IRFPA module with more than two response areas, and avoids incorrect detection to treat pixels in different response areas as bad pixels.

Abstract: The present invention relates to a scoring method for predicting the survival of a de novo AML patient based on the expression level of microRNAs mir-9, mir-155 and mir-203 in the patient. Patients with higher scores are associated with shorter overall survival. This scoring method is simple, powerful, and widely applicable for risk stratification of AML patients.