Patents by Inventor Yu-Fang Yen

Yu-Fang Yen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11714065
    Abstract: A method of measuring hematocrit is provided. The method for measuring hematocrit includes the following steps. A test strip is provided. The test strip includes a reaction region and a pair of electrodes disposed in the reaction region. A whole blood sample is entered to the reaction region. After the whole blood sample enters the reaction region, a plurality of sets of square wave voltages are intermittently applied to the pair of electrodes based on a square wave voltammetry method to obtain a plurality of feedbacks related to hematocrit. An interval between two adjacent sets of square wave voltages ranges from 0.1 seconds to 4 seconds. A feedback of an n-th set of square wave voltages is obtained to calculate a hematocrit value of the whole blood sample and n is a positive integer greater than 1. A hematocrit value is calculated according to the feedback.
    Type: Grant
    Filed: September 7, 2020
    Date of Patent: August 1, 2023
    Assignee: Industrial Technology Research Institute
    Inventors: Chu-Hsuan Chen, Yu-Fang Yen, Yi-Ting Tung, Fen-Fei Lin, Yi-Yun Yuan, Wen-Pin Hsieh
  • Publication number: 20210197162
    Abstract: An extracellular vesicle separation method, a colloidal particle, and a preparation method thereof are provided. The colloidal particle is used for extracellular vesicle separation, and includes 2 wt % to 6 wt % of agarose. The colloidal particle has a particle size of 25 ?m to 500 ?m, and is surface-modified with biocompatible molecules. The biocompatible molecules include sodium carboxymethyl cellulose (CMC), methyl cellulose (MC), glycine, aspartic acid, glutamic acid, bovine serum albumin (BSA), fetal bovine serum (FBS), or a combination thereof.
    Type: Application
    Filed: December 28, 2020
    Publication date: July 1, 2021
    Applicant: Industrial Technology Research Institute
    Inventors: Yu-Fang Yen, Chien-An Chen, Cheng-Tai Chen
  • Publication number: 20200400612
    Abstract: A method of measuring hematocrit is provided. The method for measuring hematocrit includes the following steps. A test strip is provided. The test strip includes a reaction region and a pair of electrodes disposed in the reaction region. A whole blood sample is entered to the reaction region. After the whole blood sample enters the reaction region, a plurality of sets of square wave voltages are intermittently applied to the pair of electrodes based on a square wave voltammetry method to obtain a plurality of feedbacks related to hematocrit. An interval between two adjacent sets of square wave voltages ranges from 0.1 seconds to 4 seconds. A feedback of an n-th set of square wave voltages is obtained to calculate a hematocrit value of the whole blood sample and n is a positive integer greater than 1. A hematocrit value is calculated according to the feedback.
    Type: Application
    Filed: September 7, 2020
    Publication date: December 24, 2020
    Applicant: Industrial Technology Research Institute
    Inventors: Chu-Hsuan Chen, Yu-Fang Yen, Yi-Ting Tung, Fen-Fei Lin, Yi-Yun Yuan, Wen-Pin Hsieh
  • Publication number: 20180120258
    Abstract: A method of measuring hematocrit and a method of testing blood are provided. The method for measuring hematocrit includes the following steps. A test strip is provided. The test strip includes a reaction region and a pair of electrodes disposed in the reaction region. A whole blood sample is entered to the reaction region. After the whole blood sample enters the reaction region, a set of square wave voltages is applied to the pair of electrodes based on a square wave voltammetry method to obtain a feedback related to hematocrit. A difference between an initial time when the whole blood sample enters the reaction region and an initial time when the set of square wave voltage is applied ranges from 0.1 seconds to 200 seconds. A hematocrit value is calculated according to the feedback.
    Type: Application
    Filed: October 24, 2017
    Publication date: May 3, 2018
    Applicant: Industrial Technology Research Institute
    Inventors: Chu-Hsuan Chen, Yu-Fang Yen, Yi-Ting Tung, Fen-Fei Lin, Yi-Yun Yuan, Wen-Pin Hsieh
  • Patent number: 9903832
    Abstract: The present disclosure provides a method for detecting an analyte concentration. The method includes providing a test strip, which includes a first electrode set including a first reaction area, a second electrode set including a second reaction area, and a reaction reagent layer disposed on the second reaction area. The method includes providing a blood sample and bringing the blood sample into contact with the first electrode set and the second electrode set, applying a first voltage to the first electrode set by voltammetry to obtain a first response value, calculating a hematocrit value according to the first response value, applying a second voltage to the second electrode set to obtain a second response value, and calculating the actual value of the analyte concentration by using the hematocrit value and the second response value.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: February 27, 2018
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chu-Hsuan Chen, Yu-Fang Yen, Yi-Yen Yuan, Hui-Ju Shen, Fen-Fei Lin, Yi-Ting Tung, Wen-Pin Hsieh
  • Publication number: 20160320327
    Abstract: The present disclosure provides a method for detecting an analyte concentration. The method includes providing a test strip, which includes a first electrode set including a first reaction area, a second electrode set including a second reaction area, and a reaction reagent layer disposed on the second reaction area. The method includes providing a blood sample and bringing the blood sample into contact with the first electrode set and the second electrode set, applying a first voltage to the first electrode set by voltammetry to obtain a first response value, calculating a hematocrit value according to the first response value, applying a second voltage to the second electrode set to obtain a second response value, and calculating the actual value of the analyte concentration by using the hematocrit value and the second response value.
    Type: Application
    Filed: August 28, 2015
    Publication date: November 3, 2016
    Applicant: Industrial Technology Research Institute
    Inventors: Chu-Hsuan CHEN, Yu-Fang YEN, Yi-Yen YUAN, Hui-Ju SHEN, Fen-Fei LIN, Yi-Ting TUNG, Wen-Pin HSIEH
  • Publication number: 20070227278
    Abstract: A wiper is disposed in the annular groove at either end of the nut, and the wiper is in the form of a flexible ring slightly larger than the annular groove of the nut. An annular conical surface inclined toward the annular groove is formed on the wiper for mating with the outer edge of the nut. A helical wiping portion is formed in the inner surface of each of the wiper for engaging in the screw shaft, and a plurality of slots penetrating the helical wiping portion are formed in the annular conical surface. The design of the slots not only can reduce the wiping resistance but also facilitate the discharge of foreign bodies. The wiping clearance between the helical wiping portion of the wiper and the helical groove of the nut can be adjusted by rotating or reversely rotating the wiper relative to the nut.
    Type: Application
    Filed: March 28, 2006
    Publication date: October 4, 2007
    Inventors: Chien-Wei Tsou, Yu-Fang Yen