Patents by Inventor Yu Geng

Yu Geng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250349421
    Abstract: A depth network detection method for diabetic retinopathy based on a genetic fuzzy tree. The method includes: first, enhancing a retina image to widen a lesion area, and compress a normal area; next, building a network model U-net to accurately segment images of retinal blood vessels and blood vessel tips; subsequently, performing training according to the vascular images segmented by the model and real diagnosis results, so as to construct an interpretable fuzzy decision tree; then, encoding weights of the decision tree and constructing a fitness function, and a plurality of decision trees being combined and optimized based on a genetic algorithm; and finally, introducing an accuracy index to dynamically adjust a penalty term in a loss function.
    Type: Application
    Filed: February 23, 2023
    Publication date: November 13, 2025
    Inventors: Weiping DING, Haipeng WANG, Hengrong JU, Chuansheng LIU, Yu GENG, Jiashuang HUANG, Chun CHENG, Jinxin CAO, Tingzhen QIN, Xinjie SHEN, Bairu PAN
  • Patent number: 12385157
    Abstract: A preparation method and a use of 2D MoS2 materials are provided. Molybdenum source and sulfur powder are used as raw materials, and inert gas is used as carrier gas. Through an intermediate evaporation process, the raw materials are transported to the molten glass surface and deposited into solid molybdenum sulfide. In the subsequent etching-spreading-sulfurization-precipitation process, ultra-high quality and ultra-large area MoS2 single-crystal domains are obtained under normal pressure and without hydrogenation. The single-crystal domain size of the prepared 2D MoS2 material can reach 1.5 cm, and then grow into a wafer-level 2D MoS2 material with a size of 2 inches and a thickness of 1-2 layers.
    Type: Grant
    Filed: April 16, 2025
    Date of Patent: August 12, 2025
    Assignee: University of Science and Technology Beijing
    Inventors: Yue Zhang, He Jiang, Zheng Zhang, Xiankun Zhang, Kuanglei Chen, Xiaoyu He, Yihe Liu, Ruishan Li, Yu Geng, Chao Chen
  • Patent number: 12131474
    Abstract: The present disclosure is a three-way U-Net method for accurately segmenting an uncertain boundary of a retinal blood vessel, includes: describing an uncertainty of a blood vessel boundary label, constructing an upper bound and a lower bound of the uncertain boundary based on the dilation operator and the erosion operator respectively to obtain a maximum value and a minimum value for the blood vessel boundary, and mapping the boundary with uncertain information into one range; combining an uncertainty representation of the boundary with a loss function, and designing a three-way loss function; training network parameters by adopting a stochastic gradient descent algorithm and utilizing a total loss of the three-way loss function; and designing and implements an auxiliary diagnosis application system for intelligently segmenting the retinal blood vessel with functions of the fundus data acquisition, the intelligent accurate segmentation and the auxiliary diagnosis for the retinal blood vessel.
    Type: Grant
    Filed: May 24, 2023
    Date of Patent: October 29, 2024
    Assignee: NANTONG UNIVERSITY
    Inventors: Weiping Ding, Ying Sun, Tao Hou, Xinjie Shen, Hengrong Ju, Jiashuang Huang, Haipeng Wang, Tingzhen Qin, Yu Geng, Ming Li, Haowen Xue, Zhongyi Wang
  • Publication number: 20240289952
    Abstract: The present disclosure is a three-way U-Net method for accurately segmenting an uncertain boundary of a retinal blood vessel, includes: describing an uncertainty of a blood vessel boundary label, constructing an upper bound and a lower bound of the uncertain boundary based on the dilation operator and the erosion operator respectively to obtain a maximum value and a minimum value for the blood vessel boundary, and mapping the boundary with uncertain information into one range; combining an uncertainty representation of the boundary with a loss function, and designing a three-way loss function; training network parameters by adopting a stochastic gradient descent algorithm and utilizing a total loss of the three-way loss function; and designing and implements an auxiliary diagnosis application system for intelligently segmenting the retinal blood vessel with functions of the fundus data acquisition, the intelligent accurate segmentation and the auxiliary diagnosis for the retinal blood vessel.
    Type: Application
    Filed: May 24, 2023
    Publication date: August 29, 2024
    Applicant: NANTONG UNIVERSITY
    Inventors: Weiping DING, Ying SUN, Tao HOU, Xinjie SHEN, Hengrong JU, Jiashuang HUANG, Haipeng WANG, Tingzhen QIN, Yu GENG, Ming LI, Haowen XUE, Zhongyi WANG
  • Patent number: 11837329
    Abstract: A method for classifying multi-granularity breast cancer genes based on a double self-adaptive neighborhood radius includes large-scale gene locus data are read and normalized, and a data analysis is performed on the large-scale gene loci. An optimum value K is selected by adopting a combination of contour coefficients and a PCA dimensionality reduction visualization, and a model of information granulation is adjusted. A heuristic reduction algorithm is used to implement a multi-granularity attribute reduction of a self-adaptive neighborhood radius based on a cluster center distance and a multi-granularity attribute reduction of a neighborhood radius based on an attribute inclusion degree, and big data for breast cancer genes are classified and predicted by adopting a machine learning classification algorithm based on a SVM support vector machine.
    Type: Grant
    Filed: February 22, 2022
    Date of Patent: December 5, 2023
    Assignee: NANTONG UNIVERSITY
    Inventors: Weiping Ding, Yu Geng, Jialu Ding, Hengrong Ju, Jiashuang Huang, Chun Cheng, Ying Sun, Yi Zhang, Ming Li, Tingzhen Qin, Xinjie Shen, Haipeng Wang
  • Publication number: 20230197203
    Abstract: A method for classifying multi-granularity breast cancer genes based on a double self-adaptive neighborhood radius includes large-scale gene locus data are read and normalized, and a data analysis is performed on the large-scale gene loci. An optimum value K is selected by adopting a combination of contour coefficients and a PCA dimensionality reduction visualization, and a model of information granulation is adjusted. A heuristic reduction algorithm is used to implement a multi-granularity attribute reduction of a self-adaptive neighborhood radius based on a cluster center distance and a multi-granularity attribute reduction of a neighborhood radius based on an attribute inclusion degree, and big data for breast cancer genes are classified and predicted by adopting a machine learning classification algorithm based on a SVM support vector machine.
    Type: Application
    Filed: February 22, 2022
    Publication date: June 22, 2023
    Inventors: Weiping DING, Yu GENG, Hengrong JU, Jiashuang HUANG, Chun CHENG, Ying SUN, Yi ZHANG, Ming LI, Tingzhen QIN, Xinjie SHEN, Haipeng WANG
  • Publication number: 20190204657
    Abstract: A display substrate includes a rigid substrate, a flexible substrate, a pixel structure, and bonding terminals. The rigid substrate includes a portion corresponding to a display region of the display substrate. The flexible substrate is disposed on the rigid substrate, and includes a portion corresponding to the display region and a portion corresponding to a bonding region of the display substrate. The pixel structure is disposed in a region on the flexible substrate corresponding to the display region. The bonding terminals are disposed in a region one the flexible substrate corresponding to the bonding region. The portion of the flexible substrate corresponding to the bonding region is bendable.
    Type: Application
    Filed: September 11, 2018
    Publication date: July 4, 2019
    Inventors: Binbin HU, He XU, Donglai GAO, Yu GENG, Wenbo WANG, Mingtao ZHU, Gang HAO, Guosong NAN
  • Patent number: 8202523
    Abstract: The invention provides various high mannose glycosylated polypeptides that are useful in a vaccine formulations. The invention also provides methods for making such glycosylated polypeptides and its uses in eliciting HIV-neutralizing antibodies.
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: June 19, 2012
    Assignee: ProSci, Inc.
    Inventors: Yu Geng, Robert James Luallen
  • Publication number: 20080038286
    Abstract: The invention provides various high mannose glycosylated polypeptides that are useful in a vaccine formulations. The invention also provides methods for making such glycosylated polypeptides and its uses in eliciting HIV-neutralizing antibodies.
    Type: Application
    Filed: September 22, 2006
    Publication date: February 14, 2008
    Applicant: PROSCI INC.
    Inventors: Yu Geng, Robert Luallen