Patents by Inventor Yu Ha Hwang

Yu Ha Hwang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same
    Publication number: 20100240890
    Abstract: The present invention relates to novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same. The novel benzamidine derivatives of the present invention are useful for the prevention and treatment of osteoporosis, bone fractures and allergic inflammatory diseases.
    Type: Application
    Filed: August 4, 2005
    Publication date: September 23, 2010
    Inventors: Jin Soo Lee, Seok Hoon Ahn, Young Goo Jin, Sang Mi Jin, Whui-Jung Park, Sae Kwang Ku, Yu Ha Hwang, Pan Soo Kim, Sun Shin Yi, Jei Man Ryu
  • Three dimensional structure of human derived apoptotic factor and receptor thereof x-ray crystallography and trail deletion mutant protein
    Publication number: 20040146968
    Abstract: The present invention relates to a method for preparing the crystal of human derived TRAIL protein and TRAIL receptor protein sDR5 complex and the crystal of TRAIL-sDR5 complex prepared by the method. The present invention also TRAIL relates to a three-dimensional structure of TRAIL protein in the form of complex with TRAIL receptor sDR5 as well as TRAIL protein itself, and specific residues existed in the contact central region of AA″ loop. The three-dimensional structure of TRAIL-sDR5 complex and the specific residues in the AA″ loop of the present invention can be effectively used for not only the development of TRAIL protein having the better cytotoxic activity and having the improved receptor biding affinity, which specifically kills viral infected cells or cancer cells but also molecular strategy for regulating the binding specificity between TNF and TNFR family.
    Type: Application
    Filed: September 24, 2003
    Publication date: July 29, 2004
    Inventors: Yong Ho Chung, Jei Man Ryu, Yu Ha Hwang, Jen-In Yoon, Kyung Mook Lim, Byung-Ha Oh, Sun-Shin Cha