Abstract: The application discloses a puncture device and a puncture method thereof. In the puncture device, a position limiting member is provided on the second member, and the position limiting member is used to limit the position of the first member, so that the first member can drive the second member to move toward the third member. The catheter is connected to the second member, so that the catheter can move together with the second member. The puncture needle is connected to the first member, so that the puncture needle can be driven to move when the first member moves, and the puncture needle can drive the catheter through the tissue together during puncturing. After that, the puncture needle can be withdrawn, and the catheter can be left in the tissue for subsequent surgical treatment, thereby reducing damage to the tissue during the operation.

Abstract: The present disclosure provides for a preparation method of highly concentrated antibody solution that binds to human programmed death receptor 1 (PD1). This process is able to manufacture the high concentrated antibody solution by an ultrafiltration/diafiltration (UF/DF) unit operation described herein. The UF/DF preparation method comprises a single-pass tangential flow filtration (SPTFF) as the first ultrafiltration concentration step, a buffer solution diafiltration step and a second ultrafiltration concentration step using conventional UF/DF. The process has a broad operation parameter range and maintains antibody stability and integrity.

Abstract: A rapid exchange stent delivery device is provided that relates to the technical field of stent delivery. The rapid exchange stent delivery device releases a stent toward a distal end along a guide wire, and the delivery device includes: an outer tube and an inner tube inserted inside the outer tube; a guide wire inlet is arranged on a distal end of the inner tube, and a guide wire outlet is arranged on a side wall; and the outer tube has an avoiding part extending toward the distal end to avoid and guide out the guide wire extending from the guide wire outlet, so that the outer tube can move relative to the inner tube, and the inner tube pushes the stent out of the distal end of the outer tube for release.

Abstract: In an embodiment a method for producing at least one optoelectronic device includes providing a substrate body, providing a substrate frame on the substrate body, wherein the substrate frame comprises at least one recess, providing at least one optoelectronic component on the substrate body, wherein the substrate frame and the at least one optoelectronic component are placed in relation to one another such that the at least one optoelectronic component is arranged in the at least one recess and providing a filler material in the at least one recess such that the at least one optoelectronic component is covered by the filler material, wherein the filler material is provided by a casting process.

Abstract: The present invention relates generally to the field of pharmaceutical formulations of antibodies against T cell immunoreceptor with Ig and ITIM domains (TIGIT), or antigen binding fragments thereof. The pharmaceutical formulations of the present invention exhibit a substantial degree of anti-TIGIT antibody stability after being subjected to stress conditions, accelerated and long-term storage. Also provided are methods of making and methods of using such antibody formulations.

Abstract: A three-dimensional (3D) object scanning method includes: controlling, when an invisible light source is off, a first camera device to capture a first image of the target object; and controlling, when the invisible light source is on, a second camera device to capture second images of the target object from a plurality of viewing angles. The target object is painted with invisible markers that are invisible to the first camera device when the invisible light source is off. The invisible markers are visible to the second camera device upon absorbing a light emitted by the invisible light source. The second images are used to determine 3D information of the target object.

Abstract: The present disclosure provides for a preparation method of highly concentrated antibody solution that binds to human programmed death receptor 1 (PD1). This process is able to manufacture the high concentrated antibody solution by an ultrafiltration/diafiltration (UF/DF) unit operation described herein. The UF/DF preparation method comprises mainly a first ultrafiltration concentration step, a buffer solution diafiltration step, and a second ultrafiltration concentration step. The process has a broad operation parameter range and maintains antibody stability and integrity when compared to low concentration antibody preparation.

Abstract: A 2-amino-3-hydroxy-3-methylbutyric acid and/or 2-amino-3-(4-hydroxyphenyl) butyric acid are used as natural active substances to be developed as a plant immune resistance inducer which can be used for improving the resistance of plants to biotic stress and abiotic stress and effectively prevents infection of fungi, viruses and bacteria on plants and reduces pathogenic levels, moreover, the tolerance capability of plants to high-temperature, low-temperature, drought and salt stresses can be remarkably improved. The 2-amino-3-hydroxy-3-methylbutyric acid and 2-amino-3-(4-hydroxyphenyl) butyric acid have the characteristics of safety, environmental protection and high efficiency.

Abstract: A three-dimensional (3D) object scanner includes: an object platform configured to host a target object; a projector device configured to project a first light pattern on to the target object; an LED screen that surrounds the object platform and configured to emit a second light pattern; an imaging device configured to obtain a plurality of images of the target object from multiple view angles as the target object and the imaging device are relatively rotated to multiple rotation degrees. The plurality of images include images obtained when the projector device projects the first light pattern and images obtained when the LED screen emits the second light pattern. The images are used to determine 3D information and texture information of the target object.

Abstract: An array substrate, a display panel and methods of manufacturing the same are provided. The method of manufacturing an array substrate according to an embodiment of the present disclosure includes: forming f pixel electrodes and a conductive structure on a substrate through a patterning process, wherein the pixel electrodes arranged in a first direction are connected through the conductive structure; and forming a signal line on the substrate through a patterning process, wherein the signal line and the pixel electrodes are disposed in the same layer. By means of the array substrate according to the embodiments of the present disclosure, the problem that it is not easy to discover the point defects caused by short circuit between the signal line and pixel electrodes in the related art can be solved.

Abstract: The present invention relates generally to the field of pharmaceutical formulations of antibodies against human programmed death receptor PD-1, or antigen binding fragments thereof. The formulations may further contain a histidine buffer, an inorganic salt, a sugar polyol, and a non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit low viscosity and a substantial degree of antibody stability after being subjected to thermal and other physical stress. Also provided are methods of making and methods of using such antibody formulations.

Abstract: This application is directed to device synchronization and alignment in extended reality. Two electronic devices create two maps of a scene according to two distinct coordinate systems. A first electronic device determines a device pose of a second electronic device in a first coordinate system of the first electronic device. The device pose is used to determine a transformation relationship between the two coordinate systems. The first electronic device obtains a second object pose that is measured in a second coordinate system of the second electronic device and used to render an object in a second map of the second electronic device. The second object pose is converted to a first object pose in the first coordinate system based on the transformation relationship. The object is rendered concurrently in the first and second maps of the first and second electronic devices based on the first and second object poses, respectively.

Abstract: The present invention relates generally to the field of pharmaceutical formulations of antibodies against human programmed death receptor PD-1, or antigen binding fragments thereof. The formulations may further contain a formulation buffer, a viscosity reducer, and a non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit low viscosity and a substantial degree of antibody stability after being subjected to thermal and other physical stress. Also provided are methods of making and methods of using such antibody formulations.

Abstract: The present application relates to a technical field of separating kavalactone and flavokawain, and in particular, to a method for separating flavokawain and kavalactone, kavalactone, and microencapsulated kavalactone. The separation method includes: S1. grinding root of piper methysticum, extracting by supercritical carbon dioxide and collecting a residue for later use, in which an extraction temperature is 45-50° C. and an extraction pressure is 4-8 MPa; S2. extracting the residue by supercritical carbon dioxide, and collecting extracted oil for later use, in which an extraction temperature is 60-80° C. and an extraction pressure is 20-50 MPa; S3. performing re-extraction and adsorption on the extracted oil to obtain a primary product of the kavalactone; and S4. crystallizing the primary product of kavalactone to obtain the kavalactone. The obtained kavalactone is used for microencapsulated kavalactone.

Abstract: A spindle power-on device for a mechanical discharge compound machine tool mounted on a spindle, includes a copper bush, a gear plate, bevel gears, electric bush assemblies, a chuck housing, a supporting plate, a mounting plate and a power device.

Abstract: Apparatus, system, and method for providing an augmented reality (AR) display. The system includes a panel comprising: a first linear polarizer configured to allow light from an object to transmit through as a polarized light; and a liquid crystal layer disposed on the first linear polarizer and at an opposite side with respect to the object, the liquid crystal layer comprising an array of liquid crystal pixels corresponding to AR content, each pixel configured to modify the polarized light; eyeglasses worn by a user and configured to directly receive the modified polarized light, at least one lens of the eyeglasses comprising a second linear polarizer; at least one camera configured to acquire at least one image of the user to obtain a face position of the user; and a controller configured to render the AR content based on the face position.

Abstract: This application is directed to device synchronization and alignment in extended reality. Two electronic devices create two maps of a scene according to two distinct coordinate systems. A first electronic device determines a device pose of a second electronic device in a first coordinate system of the first electronic device. The device pose is used to determine a transformation relationship between the two coordinate systems. The first electronic device obtains a second object pose that is measured in a second coordinate system of the second electronic device and used to render an object in a second map of the second electronic device. The second object pose is converted to a first object pose in the first coordinate system based on the transformation relationship. The object is rendered concurrently in the first and second maps of the first and second electronic devices based on the first and second object poses, respectively.

Abstract: A three-dimensional (3D) object scanning method includes: controlling, when an invisible light source is off, a first camera device to capture a first image of the target object; and controlling, when the invisible light source is on, a second camera device to capture second images of the target object from a plurality of viewing angles. The target object is painted with invisible markers that are invisible to the first camera device when the invisible light source is off. The invisible markers are visible to the second camera device upon absorbing a light emitted by the invisible light source. The second images are used to determine 3D information of the target object.

Abstract: A three-dimensional (3D) object scanner includes: an object platform configured to host a target object; a projector device configured to project a first light pattern on to the target object; an LED screen that surrounds the object platform and configured to emit a second light pattern; an imaging device configured to obtain a plurality of images of the target object from multiple view angles as the target object and the imaging device are relatively rotated to multiple rotation degrees. The plurality of images include images obtained when the projector device projects the first light pattern and images obtained when the LED screen emits the second light pattern. The images are used to determine 3D information and texture information of the target object.