Abstract: The present disclosure relates to a method for controlling the differentiation of embryonic stem cells into adipocytes or kidney precursor cells by regulating SIRT1 (silent mating type information regulation 2 homolog; sirtuin 1) expression, the method, which controls the differentiation of embryonic stem cells into adipocytes by regulating SIRT1 expression, being capable of controlling the inhibition or promotion of adipocyte differentiation in accordance with the timing of a SIRT1 expression inhibitor treatment. Furthermore, kidney precursor cell differentiation can be regulated by a SIRT1 expression inhibitor or promoter treatment. Accordingly, a SIRT1 inhibitor can be selected to be used as an inhibitor or a therapeutic agent for obesity, diabetes accompanying obesity, and renal and metabolic diseases.

Abstract: An electronic device is provided. The electronic device includes a memory to store an application, a communication interface to communicate with an external device, and a processor operatively connected with the memory and the communication interface. The processor determines whether the application is authenticated if receiving an installation request or an execution request of the application, generates a policy file associated with a domain of the application if the application is authenticated, and assigns the application to a specified domain, which is accessible to a secure area of the memory, based on the generated policy file.

Abstract: A copolymer includes (A) an aromatic vinyl-based monomer, (B) an unsaturated nitrile-based monomer, (C) a cross-linkable siloxane compound, and (D) an N-substituted maleimide-based monomer to realize a synergistic effect of matting characteristics and heat resistance properties. A thermoplastic resin composition including the copolymer, and a molded article including the thermoplastic resin composition are provided.

Abstract: Disclosed herein are an apparatus and method for recognizing a voice speaker. The apparatus for recognizing a voice speaker includes a voice feature extraction unit configured to extract a feature vector from a voice signal inputted through a microphone; and a speaker recognition unit configured to calculate a speaker recognition score by selecting a reverberant environment from multiple reverberant environment learning data sets based on the feature vector extracted by the voice feature extraction unit and to recognize a speaker by assigning a weight depending on the selected reverberant environment to the speaker recognition score.

Abstract: An electronic device includes a memory configured to store an application, a communication interface, and a processor. The processor is configured to receive a request to install or execute the application, verify whether the application is authenticated compare at least part of an icon for executing the application with a security indication associated with security of the application. The electronic device provides a result of comparing the at least part of the icon with the security indication based on whether the application is authenticated.

Abstract: A electronic device and a control method of the electronic device are provided. A control method includes providing a first environment in which at least one application can operate and a second environment having an operation environment at least partially different from the first environment; determining whether a first application among the at least one application is to be executed in the second environment, when an execution command of the first application is acquired; and executing the first application in the second environment, when it is determined that the first application is to be executed in the second environment.

Abstract: An aromatic vinyl-based copolymer of the present invention is a copolymer obtained in a batch polymerization reaction of aromatic vinyl monomers and cyanovinyl monomers, and is characterized by having a weight average molecular weight of about 120,000 to about 400,000 g/mol, and a yellowness index (YI) of at most about 20, as measured according to ASTM D1925 using a 3.2 mm thick specimen. The aromatic vinyl-based copolymer and a thermoplastic resin composition including the same have excellent heat resistance, color, flowability, and impact resistance and the like.

Abstract: An electronic device and method of controlling an electronic device are provided. The electronic device includes a communication module; a processor; and a memory that stores instructions to instruct the processor to install a first application operating only in a first environment, install a second application selectively operating in at least one of the first environment and a second environment, grant access to the first application to first data, the first data being generated while the second application operates in the first environment, deny access to the first application to second data, the second data being generated while the second application operates in the second environment, grant access to the second application to third data, the third data being generated while the first application operates in the first environment, and allocate the second application to at least the second environment without a user's input when the second application is installed.

Abstract: A rubber modified vinyl-based graft copolymer of the present invention has a core-shell structure in which a shell is formed by graft-polymerizing a monomer mixture to a core comprising a rubbery polymer, wherein the monomer mixture comprises: an aromatic monomer comprising an ?-substituted aromatic vinyl-based monomer represented by chemical formula 1 and an aromatic vinyl-based monomer excluding the ?-substituted aromatic vinyl-based monomer; a cyanovinyl-based monomer; and a maleimide-based monomer. A thermoplastic resin composition containing the rubber modified vinyl-based graft copolymer has excellent impact resistance, heat resistance, appearance characteristics and the like.

Abstract: The present disclosure relates to a method for controlling the differentiation of embryonic stem cells into adipocytes or kidney precursor cells by regulating SIRT1 (silent mating type information regulation 2 homolog; sirtuin 1) expression, the method, which controls the differentiation of embryonic stem cells into adipocytes by regulating SIRT1 expression, being capable of controlling the inhibition or promotion of adipocyte differentiation in accordance with the timing of a SIRT1 expression inhibitor treatment. Furthermore, kidney precursor cell differentiation can be regulated by a SIRT1 expression inhibitor or promoter treatment. Accordingly, a SIRT1 inhibitor can be selected to be used as an inhibitor or a therapeutic agent for obesity, diabetes accompanying obesity, and renal and metabolic diseases.

Abstract: An electronic device is provided. The electronic device includes a memory to store an application, a communication interface to communicate with an external device, and a processor operatively connected with the memory and the communication interface. The processor determines whether the application is authenticated if receiving an installation request or an execution request of the application, generates a policy file associated with a domain of the application if the application is authenticated, and assigns the application to a specified domain, which is accessible to a secure area of the memory, based on the generated policy file.

Abstract: A thermoplastic resin composition includes (A) a graft rubber copolymer, (B) an aromatic vinyl-vinyl cyanide-based copolymer, and (C) a silicone-modified aromatic vinyl-vinyl cyanide-based copolymer. The silicone-modified aromatic vinyl-vinyl cyanide-based copolymer (C) has an average particle size of about 100 ?m or less.

Abstract: An aromatic vinyl copolymer is a polymer of a reaction mixture including: an aromatic vinyl compound; a vinyl cyanide compound; a silicone compound having at least two unsaturated reactive groups; and a C4 to C20 linear or branched alkyl group-containing acrylic compound. A thermoplastic resin composition including the aromatic vinyl copolymer can have excellent matting properties, impact resistance, flowability, and balance therebetween.

Abstract: An aromatic vinyl copolymer is a polymer of a reaction mixture including: an aromatic vinyl compound; a vinyl cyanide compound; a first silicone compound having a weight average molecular weight of about 150 g/mol to less than about 6,000 g/mol and including at least two unsaturated reactive groups; and a second silicone compound having a weight average molecular weight of about 6,000 g/mol to about 100,000 g/mol and including at least two unsaturated reactive groups. A thermoplastic resin composition including the aromatic vinyl copolymer can exhibit excellent matting properties, impact resistance, and balance therebetween.

Abstract: The present invention relates to a pharmaceutical composition containing a SIRT2 inhibitor and, more specifically, to: a pharmaceutical composition for preventing or treating renal inflammatory diseases, which are caused by sepsis, by controlling inflammation-inducing factors by sepsis through the regulation of SIRT2 gene expression so as to reduce renal inflammation, thereby preventing a kidney injury; and a pharmaceutical composition for preventing or treating cancer, having an effect of increasing anticancer efficacy while reducing nephrotoxicity, which is a side effect of cisplatin, when administered together with cisplatin.

Abstract: An electronic device includes a memory configured to store an application, a communication interface, and a processor. The processor is configured to receive a request to install or execute the application, verify whether the application is authenticated compare at least part of an icon for executing the application with a security indication associated with security of the application. The electronic device provides a result of comparing the at least part of the icon with the security indication based on whether the application is authenticated.

Abstract: An electronic device is provided. The electronic device includes a housing of the electronic device, a memory disposed in the housing, a user interface, and a processor electrically connected with the memory and the user interface. The memory stores instructions, which, when executed, cause the processor to store encrypted content in the memory, receive an input for loading the content through the user interface, decrypt the content based at least in part on the input, store the decrypted content in the memory separately from the encrypted content, and provide the decrypted content through the user interface.

Abstract: Disclosed herein are a vinyl copolymer and a thermoplastic resin composition including the same. The vinyl copolymer is prepared by copolymerization of (A) an aromatic vinyl monomer, (B) a vinyl cyanide monomer, and (C) a dimaleimide monomer.

Abstract: An electronic device and method of controlling an electronic device are provided. The electronic device includes a communication module; a processor; and a memory that stores instructions to instruct the processor to install a first application operating only in a first environment, install a second application selectively operating in at least one of the first environment and a second environment, grant access to the first application to first data, the first data being generated while the second application operates in the first environment, deny access to the first application to second data, the second data being generated while the second application operates in the second environment, grant access to the second application to third data, the third data being generated while the first application operates in the first environment, and allocate the second application to at least the second environment without a user's input when the second application is installed.

Abstract: A electronic device and a control method of the electronic device are provided. A control method includes providing a first environment in which at least one application can operate and a second environment having an operation environment at least partially different from the first environment; determining whether a first application among the at least one application is to be executed in the second environment, when an execution command of the first application is acquired; and executing the first application in the second environment, when it is determined that the first application is to be executed in the second environment.