Patents by Inventor Yu-Ju G. Meng

Yu-Ju G. Meng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOGLOBULIN VARIANTS AND USES THEREOF
    Publication number: 20210002359
    Abstract: Variant immunoglobulins with one or more amino acid modifications in the Fe region that have increased in vivo half-lives, and methods of using the same are provided.
    Type: Application
    Filed: June 1, 2020
    Publication date: January 7, 2021
    Applicant: Genentech, Inc.
    Inventors: Henry B. LOWMAN, Yik Andy YEUNG, Lisa A. DAMICO, Napaleone FERRARA, Yu-Ju G. MENG
  • HINGE MODIFIED ANTIBODY FRAGMENTS AND METHODS OF MAKING
    Publication number: 20200308304
    Abstract: The instant disclosure provides antibody fragments (e.g., Fab and F(ab?)2) having reduced or no reactivity towards pre-existing anti-hinge antibodies (AHA) and compositions comprising such antibody fragments, as well as methods of making and using such antibody fragments and compositions.
    Type: Application
    Filed: April 17, 2020
    Publication date: October 1, 2020
    Applicant: GENENTECH, INC.
    Inventors: Yu-Ju G. Meng, Hok Seon Kim, Ingrid Kim, Christoph Spiess
  • Hinge modified antibody fragments and methods of making
    Patent number: 10662254
    Abstract: The instant disclosure provides antibody fragments (e.g., Fab and F(ab?)2) having reduced or no reactivity towards pre-existing anti-hinge antibodies (AHA) and compositions comprising such antibody fragments, as well as methods of making and using such antibody fragments and compositions.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: May 26, 2020
    Assignee: Genentech, Inc.
    Inventors: Yu-Ju G. Meng, Hok Seon Kim, Ingrid Kim, Christoph Spiess
  • HINGE MODIFIED ANTIBODY FRAGMENTS AND METHODS OF MAKING
    Publication number: 20180305462
    Abstract: The instant disclosure provides antibody fragments (e.g., Fab and F(ab?)2) having reduced or no reactivity towards pre-existing anti-hinge antibodies (AHA) and compositions comprising such antibody fragments, as well as methods of making and using such antibody fragments and compositions.
    Type: Application
    Filed: April 30, 2018
    Publication date: October 25, 2018
    Applicant: GENENTECH, INC.
    Inventors: Yu-Ju G. Meng, Hok Seon Kim, Ingrid Kim, Christoph Spiess
  • ELISA FOR VEGF
    Publication number: 20170276683
    Abstract: The vascular endothelial growth factor (VEGF) activity in a patient's bloodstream or other biological sample can serve as a diagnostic and prognostic index for cancer, diabetes, heart conditions, and other pathologies. Antibody-sandwich ELISA methods and kits for VEGF as an antigen are provided to detect types of VEGF levels in biological samples from animal models and human patients and can be used as a diagnostic/prognostic index.
    Type: Application
    Filed: March 13, 2017
    Publication date: September 28, 2017
    Inventors: Yu-Ju G. MENG, Kyu H. HONG, Johnny GUTIERREZ
  • Elisa for VEGF
    Patent number: 9625462
    Abstract: The vascular endothelial growth factor (VEGF) activity in a patient's bloodstream or other biological sample can serve as a diagnostic and prognostic index for cancer, diabetes, heart conditions, and other pathologies. Antibody-sandwich ELISA methods and kits for VEGF as an antigen are provided to detect types of VEGF levels in biological samples from animal models and human patients and can be used as a diagnostic/prognostic index.
    Type: Grant
    Filed: July 30, 2015
    Date of Patent: April 18, 2017
    Assignee: Genetech, Inc.
    Inventors: Yu-Ju G. Meng, Kyu H. Hong, Johnny Gutierrez
  • Anti-Bv8 antibodies and uses thereof
    Patent number: 9266948
    Abstract: The present invention concerns antibodies to Bv8 and the uses of same.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: February 23, 2016
    Assignee: Genentech, Inc.
    Inventors: Xiumin Wu, Van Wu, Lanlan Yu, Napoleone Ferrara, Wei-Ghing Liang, Yu-Ju G. Meng, Janet Tien
  • ELISA FOR VEGF
    Publication number: 20160033517
    Abstract: The vascular endothelial growth factor (VEGF) activity in a patient's bloodstream or other biological sample can serve as a diagnostic and prognostic index for cancer, diabetes, heart conditions, and other pathologies. Antibody-sandwich ELISA methods and kits for VEGF as an antigen are provided to detect types of VEGF levels in biological samples from animal models and human patients and can be used as a diagnostic/prognostic index.
    Type: Application
    Filed: July 30, 2015
    Publication date: February 4, 2016
    Inventors: Yu-Ju G. MENG, Kyu H. HONG, Johnny GUTIERREZ
  • ELISA for VEGF
    Patent number: 9146245
    Abstract: The vascular endothelial growth factor (VEGF) activity in a patient's bloodstream or other biological sample can serve as a diagnostic and prognostic index for cancer, diabetes, heart conditions, and other pathologies. Antibody-sandwich ELISA methods and kits for VEGF as an antigen are provided to detect types of VEGF levels in biological samples from animal models and human patients and can be used as a diagnostic/prognostic index.
    Type: Grant
    Filed: October 25, 2012
    Date of Patent: September 29, 2015
    Assignee: Genentech, Inc.
    Inventors: Yu-Ju G. Meng, Kyu H. Hong, Johnny Gutierrez
  • Anti-Bv8 Antibodies and Uses Thereof
    Publication number: 20140377860
    Abstract: The present invention concerns antibodies to Bv8 and the uses of same.
    Type: Application
    Filed: May 29, 2014
    Publication date: December 25, 2014
    Inventors: Xiumin Wu, Yan Wu, Lanlan Yu, Napoleone Ferrara, Wei-Ching Liang, Yu-Ju G. Meng, Janet Tien
  • IMMUNOGLOBULIN VARIANTS AND USES THEREOF
    Publication number: 20140294810
    Abstract: Variant immunoglobulins with one or more amino acid modifications in the Fc region that have increased in vivo half-lives, and methods of using the same are provided.
    Type: Application
    Filed: February 24, 2014
    Publication date: October 2, 2014
    Applicant: GENENTECH, INC.
    Inventors: Henry B. LOWMAN, Yik Andy YEUNG, Lisa A. DAMICO, Napaleone FERRARA, Yu-Ju G. MENG
  • Anti-BV8 antibodies and uses thereof
    Patent number: 8771685
    Abstract: The present invention concerns antibodies to Bv8 and the uses of same.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: July 8, 2014
    Assignee: F. Hoffmann-La Roche AG
    Inventors: Xiumin Wu, Yan Wu, Lanlan Yu, Napoleone Ferrara, Wei-Ching Liang, Yu-Ju G. Meng, Janet Tien
  • Anti-VEGF antibodies
    Patent number: 8449885
    Abstract: The vascular endothelial growth factor (VEGF) activity in a patient's bloodstream or other biological sample can serve as a diagnostic and prognostic index for cancer, diabetes, heart conditions, and other pathologies. Antibody-sandwich ELISA methods and kits for VEGF as an antigen are provided to detect types of VEGF levels in biological samples from animal models and human patients and can be used as a diagnostic/prognostic index.
    Type: Grant
    Filed: June 17, 2010
    Date of Patent: May 28, 2013
    Assignee: Genentech, Inc.
    Inventors: Yu-Ju G. Meng, Kyu H. Hong, Johnny Gutierrez
  • ELISA FOR VEGF
    Publication number: 20130045495
    Abstract: The vascular endothelial growth factor (VEGF) activity in a patient's bloodstream or other biological sample can serve as a diagnostic and prognostic index for cancer, diabetes, heart conditions, and other pathologies. Antibody-sandwich ELISA methods and kits for VEGF as an antigen are provided to detect types of VEGF levels in biological samples from animal models and human patients and can be used as a diagnostic/prognostic index.
    Type: Application
    Filed: October 25, 2012
    Publication date: February 21, 2013
    Inventors: Yu-Ju G. MENG, Kyu H. Hong, Johnny GUTIERREZ
  • ANTI-BV8 ANTIBODIES AND USES THEREOF
    Publication number: 20120014941
    Abstract: The present invention concerns antibodies to Bv8 and the uses of same.
    Type: Application
    Filed: December 22, 2010
    Publication date: January 19, 2012
    Inventors: Xiumin Wu, Yan Wu, Lanlan Yu, Napoleone Ferrara, Wei-Ching Liang, Yu-Ju G. Meng, Janet Tien
  • ELISA FOR VEGF
    Publication number: 20100255515
    Abstract: The vascular endothelial growth factor (VEGF) activity in a patient's bloodstream or other biological sample can serve as a diagnostic and prognostic index for cancer, diabetes, heart conditions, and other pathologies. Antibody-sandwich ELISA methods and kits for VEGF as an antigen are provided to detect types of VEGF levels in biological samples from animal models and human patients and can be used as a diagnostic/prognostic index.
    Type: Application
    Filed: June 17, 2010
    Publication date: October 7, 2010
    Applicant: Genentech, Inc.
    Inventors: Yu-Ju G. Meng, Kyu H. Hong, Johnny Gutierrez
  • IMMUNOGLOBULIN VARIANTS AND USES THEREOF
    Publication number: 20100098730
    Abstract: Variant immunoglobulins with one or more amino acid modifications in the Fc region that have increased in vivo half-lives, and methods of using the same are provided.
    Type: Application
    Filed: October 13, 2009
    Publication date: April 22, 2010
    Inventors: Henry B. Lowman, Yik Andy Yeung, Lisa A. Damico, Napoleone Ferrara, Yu-Ju G. Meng
  • COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR
    Publication number: 20090181014
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: September 29, 2006
    Publication date: July 16, 2009
    Applicant: Genentech, Inc.
    Inventors: Heidi S. Phillips, Yu-Ju G. Meng, Richard L. Vandlen
  • ELISA for VEGF
    Publication number: 20080227119
    Abstract: The vascular endothelial growth factor (VEGF) activity in a patient's bloodstream or other biological sample can serve as a diagnostic and prognostic index for cancer, diabetes, heart conditions, and other pathologies. Antibody-sandwich ELISA methods and kits for VEGF as an antigen are provided to detect types of VEGF levels in biological samples from animal models and human patients and can be used as a diagnostic/prognostic index.
    Type: Application
    Filed: October 3, 2007
    Publication date: September 18, 2008
    Applicant: Genentech, Inc.
    Inventors: Yu-Ju G. Meng, Kyu H. Hong, Johnny Gutierrez
  • PCR assay
    Patent number: 6927024
    Abstract: An oligonucleotide assay is useful for the detection of target compounds in samples which may contain the target compound.
    Type: Grant
    Filed: November 24, 1999
    Date of Patent: August 9, 2005
    Assignee: Genentech, Inc.
    Inventors: Anthony H. Dodge, Yu-Ju G. Meng, Paul W. Sims, Dominick V. Sinicropi, P. Mickey Williams, Wai Lee Wong