Abstract: An IC spatial array for a captured ligand assay is described. Materials to prepare and methods to produce the IC spatial array are also provided. The IC spatial array includes a matrix substrate including capture probes anchored to the matrix substrate such that the capture probes have a barcode unique to the capture probe's spatial location within the matrix substrate and the capture probe has a free end for capturing analytes from a sample.

Abstract: The present invention provides engineered models that recapitulate bone marrow, including the endosteal and vascular niches, and bone marrow diseases. The models can be implemented in many ways including, but not limited to, on a microfluidic device or microfluidic chip, a culture model in vitro, and as an implantable model in vivo. Also provided are methods of using these models, including high-throughput systems and in personalized medicine analysis. Also provided are devices for use in the provided bone marrow models, and kits that include at least one such device.

Abstract: A display device includes at least one peripheral pixel, at least one non-peripheral pixel and a black matrix. The at least one peripheral pixel includes a first color resist, a second color resist adjacent to the first color resist and a third color resist adjacent to the second color resist. The at least one non-peripheral pixel is adjacent to the at least one peripheral pixel. The at least one non-peripheral pixel includes a fourth color resist. The black matrix at least overlaps at least one of the first color resist, the second color resist and the third color resist.