Abstract: The present disclosure describes a combination therapy comprising an antagonist of Programmed Death 1 receptor (PD-1), a lenvatinib or a pharmaceutically acceptable salt thereof, and (6S,9aS)-N-benzyl-8-({6-[3-(4-ethylpiperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-6-(2-fluoro-4-hydroxybenzyl)-4,7-dioxo-2-(prop-2-en-1-yl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide (E7386) or a pharmaceutically acceptable salt thereof,—and the use of the combination therapies for the treatment of a cancer.

Abstract: [Problem] Provided are a photoelectric conversion device and an imaging apparatus capable of improving quantum efficiency and a response speed. [Solving means] A first photoelectric conversion device according to one embodiment of the present disclosure includes a first electrode, a second electrode opposed to the first electrode, and a photoelectric conversion layer. The photoelectric conversion layer is provided between the first electrode and the second electrode and includes at least one type of one organic semiconductor material having crystallinity. Variation in a ratio between horizontally-oriented crystal and vertically-oriented crystal in the photoelectric conversion layer is three times or less between a case where film formation of the one organic semiconductor material is performed at a first temperature and a case where the film formation of the one organic semiconductor material is performed at a second temperature. The second temperature is higher than the first temperature.

Abstract: [Problem] The present invention provides a stereoscopic image display device, stereoscopic image display method, and a program capable of displaying the display target with a constant size and a constant aspect ratio even when the distance between the stereoscopic image display device and the user changes. [Solution to Problem] The present invention provides a stereoscopic image display device comprising: a display part; an acquisition part configured to acquire an observation viewing distance that is a viewing distance from the display part to a user; and an adjustment part configured to adjust a display state of a display image based on a reference viewing distance and the observation viewing distance, wherein the display part is configured to display a stereoscopic image based on the display state.

Abstract: The present invention has been made in view of the foregoing, and an object thereof is to provide a method for learning a threshold that can provide a more objective threshold applied to pixels in the mammography image. The present invention provides a method for learning a threshold value applied to pixels in a mammography image comprising: an acquiring step; and a learning step, wherein in the acquiring step, the mammography image is acquired, in the learning step, a relationship between the mammography image and a mammary gland pixel estimation threshold is learned, the mammary gland pixel estimation threshold is a threshold value used to calculate a mammary gland pixel area of each pixel of a mammary gland region in the mammography image, and the mammary gland pixel area is a value indicating a degree of a mammary gland pixel-likeness of the pixel in the mammography image.

Abstract: A recovery device for a volatile organic compound is a device for recovering the volatile organic compound in a coating drying oven which dries a coating film of a workpiece coated with a water-soluble coating. The coating drying oven includes: an evaporation zone in which moisture of the workpiece is evaporated; and a curing zone to cure the coating film. The recovery device includes: a first take-out passage for taking out first furnace air in the evaporation zone; a second take-out passage for taking out second furnace air in the curing zone; a mixing chamber configured to mix the first furnace air and the second furnace air to obtain mixed air; and a cooling recovery unit configured to cool the mixed air and recover, as a condensate, the volatile organic compound contained in the mixed air, together with the moisture.

Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a multi-RTK inhibitor, and the use of the combination therapies for the treatment of cancer. The multi-RTK inhibitor may be represented by Formula (I): wherein R1 is C1-6 alkyl or C3-8 cycloalkyl, R2 is a hydrogen atom or C1-6 alkoxy, and R3 is a hydrogen atom or a halogen atom. A tumor therapeutic agent is disclosed that combines a compound or pharmaceutically acceptable salt thereof represented by Formula I and an anti-PD-1 antibody.

Abstract: A photoelectric conversion element including a first electrode and a second electrode that are disposed to face each other and a photoelectric conversion layer that is provided between the first electrode and the second electrode. The photoelectric conversion layer contains at least a subphthalocyanine or a subphthalocyanine derivative, and a carrier dopant, in which the carrier dopant has a concentration of less than 1% by volume ratio to the subphthalocyanine or the subphthalocyanine derivative.

Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a multi-RTK inhibitor, and the use of the combination therapies for the treatment of cancer. The multi-RTK inhibitor may be represented by Formula (I): wherein R1 is C1-6 alkyl or C3-8 cycloalkyl, R2 is a hydrogen atom or C1-6 alkoxy, and R3 is a hydrogen atom or a halogen atom. A tumor therapeutic agent is disclosed that combines a compound or pharmaceutically acceptable salt thereof represented by Formula I and an anti-PD-1 antibody.

Abstract: A photoelectric conversion element according to an embodiment of the disclosure includes a first electrode and a second electrode that are disposed to face each other and a photoelectric conversion layer that is provided between the first electrode and the second electrode, and contains at least a subphthalocyanine or a subphthalocyanine derivative, and a carrier dopant, in which the carrier dopant has a concentration of less than 1% by volume ratio to the subphthalocyanine or the subphthalocyanine derivative.

Abstract: An organic EL device is constructed with a structure that can prevent deterioration in characteristics. An organic EL device (100) is provided that includes at least two or more subpixels (110) each including an organic compound layer (117) including at least a light-emitting layer that emits light of a different color from the other light-emitting layer(s), the organic compound layer being interposed between a first electrode (118) and a second electrode (116) in a stacking manner, the subpixels being disposed separately from one another on a plane perpendicular to a direction of the stacking. Lateral surfaces of the organic compound layers are covered with films differing from subpixel to subpixel. This structure can prevent the organic EL device from deterioration in characteristics.

Abstract: [Problem] The present invention provides a stereoscopic image display device, stereoscopic image display method, and a program capable of displaying the display target with a constant size and a constant aspect ratio even when the distance between the stereoscopic image display device and the user changes. [Solution to Problem] The present invention provides a stereoscopic image display device comprising: a display part; an acquisition part configured to acquire an observation viewing distance that is a viewing distance from the display part to a user; and an adjustment part configured to adjust a display state of a display image based on a reference viewing distance and the observation viewing distance, wherein the display part is configured to display a stereoscopic image based on the display state.

Abstract: The present invention has been made in view of the foregoing, and an object thereof is to provide an information processing device capable of appropriately determining a necessity of the ultrasonography even when a high-density mammary gland area exists in a narrow area. The present invention provides an information processing device comprising: a mammary gland area extractor configured to extract a mammary gland area in a mammography image; a mammary gland pixel detector configured to detect a mammary gland pixel in the mammary gland area; and a mammary gland density calculator configured to calculate a mammary gland density based on a ratio of the mammary gland pixels to the mammary gland area, wherein the mammary gland area is a narrower area than an entire breast in the mammography image.

Abstract: There is provided an imaging device including an upper electrode; a lower electrode; a photoelectric conversion layer disposed between the upper electrode and the lower electrode; and a first organic semiconductor material including an indolocarbazole derivative and disposed between the upper electrode and the lower electrode. Further, there is provided an electronic apparatus including an imaging device that includes an upper electrode; a lower electrode; a photoelectric conversion layer disposed between the upper electrode and the lower electrode; and a first organic semiconductor material including an indolocarbazole derivative and disposed between the upper electrode and the lower electrode.

Abstract: A drive power transmission apparatus for a vehicle, includes an oil pump, an oil strainer connected to the oil pump, a differential gear mechanism, and a housing case including a first chamber in which the oil strainer is disposed and a second chamber in which the differential gear mechanism is disposed, the second chamber communicating with the first chamber via a communication port, and the oil strainer has a suction port that is not surrounded by a rib, and has a first rib disposed between the suction port and the communication port.

Abstract: There is provided an imaging device including an upper electrode; a lower electrode; a photoelectric conversion layer disposed between the upper electrode and the lower electrode; and a first organic semiconductor material including an indolocarbazole derivative and disposed between the upper electrode and the lower electrode. Further, there is provided an electronic apparatus including an imaging device that includes an upper electrode; a lower electrode; a photoelectric conversion layer disposed between the upper electrode and the lower electrode; and a first organic semiconductor material including an indolocarbazole derivative and disposed between the upper electrode and the lower electrode.

Abstract: A photoelectric conversion element according to an embodiment of the disclosure includes a first electrode and a second electrode that are disposed to face each other and a photoelectric conversion layer that is provided between the first electrode and the second electrode, and contains at least a subphthalocyanine or a subphthalocyanine derivative, and a carrier dopant, in which the carrier dopant has a concentration of less than 1% by volume ratio to the subphthalocyanine or the subphthalocyanine derivative.

Abstract: [Problem] Provided are a photoelectric conversion device and an imaging apparatus capable of improving quantum efficiency and a response speed. [Solving means] A first photoelectric conversion device according to one embodiment of the present disclosure includes a first electrode, a second electrode opposed to the first electrode, and a photoelectric conversion layer. The photoelectric conversion layer is provided between the first electrode and the second electrode and includes at least one type of one organic semiconductor material having crystallinity. Variation in a ratio between horizontally-oriented crystal and vertically-oriented crystal in the photoelectric conversion layer is three times or less between a case where film formation of the one organic semiconductor material is performed at a first temperature and a case where the film formation of the one organic semiconductor material is performed at a second temperature. The second temperature is higher than the first temperature.

Abstract: A photoelectric conversion element according to an embodiment of the disclosure includes a first electrode and a second electrode that are disposed to face each other and a photoelectric conversion layer that is provided between the first electrode and the second electrode, and contains at least a subphthalocyanine or a subphthalocyanine derivative, and a carrier dopant, in which the carrier dopant has a concentration of less than 1% by volume ratio to the subphthalocyanine or the subphthalocyanine derivative.

Abstract: Non-liposome, non-micelle particles formed of a lipid, an additional adjuvant such as a TLR4 agonist, a sterol, and a saponin are provided. The particles are porous, cage-like nanoparticles, also referred to as nanocages, and are typically between about 30 nm and about 60 nm. In some embodiments, the nanocages include or are administered in combination with an antigen. The particles can increase immune responses and are particularly useful as adjuvants in vaccine applications and related methods of treatment. Preferred lipids, additional adjuvants including TLR4 agonists, sterols, and saponins, methods of making the nanocages, and method of using them are also provided.

Abstract: There is provided an imaging device including an upper electrode; a lower electrode; a photoelectric conversion layer disposed between the upper electrode and the lower electrode; and a first organic semiconductor material including an indolocarbazole derivative and disposed between the upper electrode and the lower electrode. Further, there is provided an electronic apparatus including an imaging device that includes an upper electrode; a lower electrode; a photoelectric conversion layer disposed between the upper electrode and the lower electrode; and a first organic semiconductor material including an indolocarbazole derivative and disposed between the upper electrode and the lower electrode.