Abstract: A holdover mode device is illustrated. When a time synchronization source is not abnormal, a digital PLL uses a time synchronization source as its input clock, and a measurement and adjustment module calculates a variation of a frequency difference between the time synchronization source and a reference clock output by an adjustable oscillator, and builds a frequency difference prediction model according to the variation of the frequency difference. When the time synchronization source is abnormal, the digital PLL uses a buffered time synchronization source as its input clock, and the measurement and adjustment module uses the frequency difference prediction model to calculate a predicted variation of the frequency difference according to buffered frequency difference values, and generates an adjustment signal for adjusting the reference clock according to the predicted variation of the frequency difference.

Abstract: A weaning readiness indicator is disclosed. The weaning readiness indicator includes a monitor, a memory, a processor, and a display. The monitor monitors a ventilated patient for a predetermined time length and generates a respiratory signal. The memory stores an algorithm, where the algorithm includes performing a nonlinear time frequency analysis on the respiratory signal to obtain a time frequency representation function, extracting one or more features from the time frequency representation function, and computing a weaning readiness index based on the one or more features. The processor is connected to the monitor and the memory, and executes the algorithm. The display is connected to the processor and provides an indication of the weaning readiness index of the ventilated patient. A sleeping status recording device and an air providing system applying nonlinear time frequency analysis are also disclosed.

Abstract: A weaning readiness indicator is disclosed. The weaning readiness indicator includes a monitor, a memory, a processor, and a display. The monitor monitors a ventilated patient for a predetermined time length and generates a respiratory signal. The memory stores an algorithm, where the algorithm includes performing a nonlinear time frequency analysis on the respiratory signal to obtain a time frequency representation function, extracting one or more features from the time frequency representation function, and computing a weaning readiness index based on the one or more features. The processor is connected to the monitor and the memory, and executes the algorithm. The display is connected to the processor and provides an indication of the weaning readiness index of the ventilated patient. A sleeping status recording device and an air providing system applying nonlinear time frequency analysis are also disclosed.

Abstract: Disclosed are the nanoparticle and the method for the same, and the preparing method includes steps of mixing polyethylenimine (PEI) with the poly(acrylic acid)-bound iron oxide (PAAIO) to form a PEI-PAAIO polyelectrolyte complex (PEC) and mixing the PEI-PAAIO PEC with genetic material such as plasmid DNA to form the PEI-PAAIO/pDNA magnetic nanoparticle. The PEI-PAAIO/pDNA magnetoplex is highly water dispersible and suitable for long term storage, shows superparamagnetism, low cytotoxicity, high stability and nice transfection efficiency, and thus the PEI-PAAIO PEC can replace PEI as a non-viral gene vector.

Abstract: The present invention discloses a gene carrier and the preparation method thereof. Chondroitin sulfate (CS) is reacted with methacrylic anhydride (MA) to form chrondroitin sulfate-methacrylate (CSMA), which is further covalently bound with polyethylenimine (PEI) via the Michael addition to produce a CSMA-PEI gene carrier. The CSMA-PEI gene carrier can effectively reduce the cytotoxicity of PEI and enhance the transfection efficiency of PEI.

Abstract: Disclosed are the nanoparticle and the method for the same, and the preparing method includes steps of mixing polyethylenimine (PEI) with the poly(acrylic acid)-bound iron oxide (PAAIO) to form a PEI-PAAIO polyelectrolyte complex (PEC) and mixing the PEI-PAAIO PEC with genetic material such as plasmid DNA to form the PEI-PAAIO/pDNA magnetic nanoparticle. The PEI-PAAIO/pDNA magnetoplex is highly water dispersible and suitable for long term storage, shows superparamagnetism, low cytotoxicity, high stability and nice transfection efficiency, and thus the PEI-PAAIO PEC can replace PEI as a non-viral gene vector.

Abstract: The present invention discloses a gene carrier and the preparation method thereof. Chondroitin sulfate (CS) is reacted with methacrylic anhydride (MA) to form chrondroitin sulfate-methacrylate (CSMA), which is further covalently bound with polyethylenimine (PEI) via the Michael addition to produce a CSMA-PEI gene carrier. The CSMA-PEI gene carrier can effectively reduce the cytotoxicity of PEI and enhance the transfection efficiency of PEI.

Abstract: Disclosed are the nanoparticle and the method for the same, and the preparing method includes steps of mixing polyethylenimine (PEI) with the poly(acrylic acid)-bound iron oxide (PAAIO) to form a PEI-PAAIO polyelectrolyte complex (PEC) and mixing the PEI-PAAIO PEC with genetic material such as plasmid DNA to form the PEI-PAAIO/pDNA magnetic nanoparticle. The PEI-PAAIO/pDNA magnetoplex is highly water dispersible and suitable for long term storage, shows superparamagnetism, low cytotoxicity, high stability and nice transfection efficiency, and thus the PEI-PAAIO PEC can replace PEI as a non-viral gene vector.

Abstract: A visual input/output device with a light shield is disclosed. The device includes an active area for performing visual input/output tasks, and a non-active area surrounding the active area in the peripheral area of the device. The light shield is formed in the non-active area for substantially preventing unwanted light from interfering with the active area. The light shield is formed on a same layer as a color filter in the active area, and the light shield is made of black pigment or carbon.