Abstract: A brush head and a toothbrush with the brush head are provided. The brush head includes a body having a front end, a back end opposing the front end, and two opposite sides; and a brush member mounted on a surface of the body and being formed with a plurality of bristles, wherein the plurality of bristles define a brush surface that slopes in relation to the surface of the body. The brush surface of the bristles can closely abut against the teeth and the gingival sulcus, and the cleaning effect of tooth brushing is efficiently enhanced using the toothbrush with the brush head, thereby overcoming the drawbacks of the prior art.