Abstract: The present invention relates to a cosmetic composition for improving skin conditions that has an effect of enhancing skin defense, improving skin moisturizing, and strengthening a skin barrier, and has an antimicrobial activity. According to the present invention, production and activities of antimicrobial peptides in keratinocytes may be significantly increased, growth of Staphylococcus may be effectively inhibited, and a synergy effect may be imparted to gene expression of a skin moisturizing factor and an intercellular binding factor, such that a synergistic effect in improving skin conditions may be obtained without side effects.

Abstract: Provided are a cosmetic composition for promoting lipid biosynthesis, a cosmetic composition for inducing differentiation of adipose precursor cells or stem cells into adipocytes, and a cosmetic composition for moisturizing the skin, all of which include an amide-based compound. The cosmetic composition according to the present invention can promote the lipid biosynthesis and can promote expression of PPAR-? and cluster of differentiation 44, which are markers for labeling human adipose tissue-derived stem cells, to promote differentiation of the adipose tissue-derived stem cells into mature adipocytes, thereby improving a decreased volume and an impaired function of an adipose tissue caused due to the involution of the adipose tissue and giving a synergistic effect to the expression of a skin moisturizing factor.

Abstract: Provided is a cosmetic composition for protection of the skin against reactive oxygen species, ultraviolet rays, or blue light, which includes an amide-based compound. The cosmetic composition according to the present invention can effectively inhibit cell damage caused by the reactive oxygen species, the ultraviolet rays, or the blue light and protect the skin without irritating the skin, and can simultaneously aid in recovering the damaged skin.

Abstract: Provided are a cosmetic composition for inhibiting sebum hypersecretion and a method of inhibiting sebum hypersecretion using the same. According to the present invention, there may be provided the cosmetic composition of inhibiting and adjusting sebum secretion which is harmless to the human body with excellent skin safety and decreases activity of peroxisome proliferator activated receptor gamma (PPAR-?) to fundamentally decrease sebum overproduction, thereby providing the skin with an effective effect, and a method of using the same.

Abstract: The present invention relates to a cosmetic composition for improving skin conditions that has an effect of enhancing skin defense, improving skin moisturizing, and strengthening a skin barrier, and has an antimicrobial activity. According to the present invention, production and activities of antimicrobial peptides in keratinocytes may be significantly increased, growth of Staphylococcus may be effectively inhibited, and a synergy effect may be imparted to gene expression of a skin moisturizing factor and an intercellular binding factor, such that a synergistic effect in improving skin conditions may be obtained without side effects.

Abstract: Provided are a novel amide compound and a use thereof. According to the present invention, there may be provided a use of a novel amide compound which is harmless to the human body with excellent skin stability and decreases activity of peroxisome proliferator activated receptor gamma (PPAR-?) to fundamentally inhibit sebum overproduction, thereby providing the skin with an effective effect, and a cosmetic composition including the same.

Abstract: Provided is a cosmetic composition for protection of the skin against reactive oxygen species, ultraviolet rays, or blue light, which includes an amide-based compound. The cosmetic composition according to the present invention can effectively inhibit cell damage caused by the reactive oxygen species, the ultraviolet rays, or the blue light and protect the skin without irritating the skin, and can simultaneously aid in recovering the damaged skin.

Abstract: Provided are a cosmetic composition for promoting lipid biosynthesis, a cosmetic composition for inducing differentiation of adipose precursor cells or stem cells into adipocytes, and a cosmetic composition for moisturizing the skin, all of which include an amide-based compound. The cosmetic composition according to the present invention can promote the lipid biosynthesis and can promote expression of PPAR-? and cluster of differentiation 44, which are markers for labeling human adipose tissue-derived stem cells, to promote differentiation of the adipose tissue-derived stem cells into mature adipocytes, thereby improving a decreased volume and an impaired function of an adipose tissue caused due to the involution of the adipose tissue and giving a synergistic effect to the expression of a skin moisturizing factor.

Abstract: Provided are a cosmetic composition for inhibiting sebum hypersecretion and a method of inhibiting sebum hypersecretion using the same. According to the present invention, there may be provided the cosmetic composition of inhibiting and adjusting sebum secretion which is harmless to the human body with excellent skin safety and decreases activity of peroxisome proliferator activated receptor gamma (PPAR-?) to fundamentally decrease sebum overproduction, thereby providing the skin with an effective effect, and a method of using the same.

Abstract: Provided are a novel amide compound and a use thereof. According to the present invention, there may be provided a use of a novel amide compound which is harmless to the human body with excellent skin stability and decreases activity of peroxisome proliferator activated receptor gamma (PPAR-?) to fundamentally inhibit sebum overproduction, thereby providing the skin with an effective effect, and a cosmetic composition including the same.