Publication number: 20160201138
Abstract: The disclosure discloses a method and markers for assessing the risk of having colorectal cancer for an individual by a stool sample. The method includes: detecting expression levels of a first microRNA and a second microRNA in the stool sample; and assessing the risk of having colorectal cancer for the individual based on a ratio between the expression levels of the first microRNA and the second microRNA. Here, the first microRNA is miR-223, miR-25, or miR-93, and the second microRNA is miR-221, miR-222, miR-21, miR-93, miR-141, miR-200c, miR-191, miR-17, miR-148a, miR-106a, miR-195, miR-20a, miR-181b, miR-145, miR-155, miR-106b, miR-24, miR-19b, miR-130b, or miR-18a. When the first microRNA is miR-93, the second microRNA is miR-17, miR-106a, miR-195, miR-20a, miR-181b, miR-155, miR-24, miR-19b, or miR-18a.
Type:
Application
Filed:
October 30, 2015
Publication date:
July 14, 2016
Inventors:
Jinn- Shiun CHEN, Yu-Sun CHANG, Err-Cheng CHAN, Chia-Chun CHEN, Pi-Yueh CHANG