Patents by Inventor Yu-Xiang Liang
Yu-Xiang Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11839694Abstract: Compositions that include nanoscale structured materials or precursors thereof (e.g., self: assembling peptides) are described. The compositions can include other substances (e.g., a vasoconstrictor). Also described are methods for using the compositions to promote hemostasis, to protect the skin or wounds from contamination, to decontaiminate a site upon removal of previously applied compositions that provided a protective coating, and to inhibit the movement of bodily substances other than blood. The compositions are also useful in isolating tissue, removing tissue, preserving tissue (for, e.g., subsequent transplantation or reattachment), and as bulking, stabilizing or hydrating agents. Medical devices that include the compositions (e.g., a stent or catheter), bandages or other wound dressings, sutures, and kits that include the compositions are also described.Type: GrantFiled: April 5, 2016Date of Patent: December 12, 2023Assignees: Massachusetts Institute of Technology, Versitech LimitedInventors: Rutledge Ellis-Behnke, Yu-Xiang Liang, Gerald E. Schneider, Kwok-Fai So, David K. C. Tay, Shuguang Zhang
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Patent number: 10137166Abstract: Compositions which self-assemble under physiological conditions are formulated for application to wounds. The formulations include a pharmaceutically acceptable carrier or are provided as part of a medical device or coating. The formulations may also include other therapeutic, prophylactic or diagnostic agents. The formulation can be administered for treatment of one or more disorders or conditions. For example, the formulation may be applied to repair an injury or during surgery of the lung, eye or dura, or following an epidural or spinal tap, to stop leakage of blood, interstitial fluid, or cerebrospinal fluid. The formulation may be administered to a burn or ulcer. In one embodiment, the formulation is provided as a dry or lyophilized powder. In another embodiment, the material is provided in water. In another embodiment, the material is provided in combination with an oil and forms a laminate.Type: GrantFiled: November 2, 2016Date of Patent: November 27, 2018Assignees: Massachusetts Institute of Technology, Versitech LimitedInventors: Rutledge Ellis-Behnke, Yu-Xiang Liang, Gerald E. Schneider, Kwok-Fai So, David K. C. Tay
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Publication number: 20170143788Abstract: Compositions which self-assemble under physiological conditions are formulated for application to wounds. The formulations include a pharmaceutically acceptable carrier or are provided as part of a medical device or coating. The formulations may also include other therapeutic, prophylactic or diagnostic agents. The formulation can be administered as appropriate for treatment of one or more disorders or conditions. For example, the formulation may be applied to repair an injury or during surgery of the lung, eye or dura, or following an epidural or spinal tap, to stop leakage of blood, interstitial fluid, or cerebrospinal fluid. The formulation may be administered to a burn or ulcer. The formulation may be dispersed in a suture or adhesive for administration at the time of or as released following suturing or gluing of a wound, thereby limiting bleeding, loss of tissue fluids, or other fluids such as those produced by parenchymal tissues such as the liver, pancreas, and gastrointestinal tract.Type: ApplicationFiled: November 2, 2016Publication date: May 25, 2017Applicants: Massachusetts Institute of Technology, Versitech LimitedInventors: Rutledge Ellis-Behnke, Yu-Xiang Liang, Gerald E. Schneider, Kwok-Fai So, David K.C. Tay
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Patent number: 9511113Abstract: Method are described for inhibiting movement of a bodily fluid and/or contaminants on or in an animal comprising administering to the animal self-assembling peptidomimetics, including ?-peptides, ?-peptides, ?-peptides, and/or ?-peptides.Type: GrantFiled: June 23, 2015Date of Patent: December 6, 2016Assignees: Massachusetts Institute of Technology, Versitech LimitedInventors: Rutledge Ellis-Behnke, Yu-Xiang Liang, Gerald E. Schneider, Kwok-Fai So, David K. C. Tay
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Publication number: 20160296660Abstract: Compositions that include nanoscale structured materials or precursors thereof (e.g., self: assembling peptides) are described. The compositions can include other substances (e.g., a vasoconstrictor). Also described are methods for using the compositions to promote hemostasis, to protect the skin or wounds from contamination, to decontaiminate a site upon removal of previously applied compositions that provided a protective coating, and to inhibit the movement of bodily substances other than blood. The compositions are also useful in isolating tissue, removing tissue, preserving tissue (for, e.g., subsequent transplantation or reattachment), and as bulking, stabilizing or hydrating agents. Medical devices that include the compositions (e.g., a stent or catheter), bandages or other wound dressings, sutures, and kits that include the compositions are also described.Type: ApplicationFiled: April 5, 2016Publication date: October 13, 2016Applicants: Massachusetts Institute of Technology, Versitech LimitedInventors: Rutledge Ellis-Behnke, Yu-Xiang Liang, Gerald E. Schneider, Kwok-Fai So, David K.C. Tay, Shuguang Zhang
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Patent number: 9364513Abstract: Compositions that include nanoscale structured materials or precursors thereof (e.g., self-assembling peptides) are described. The compositions can include other substances (e.g., a vasoconstrictor). Also described are methods for using the compositions to promote hemostasis, to protect the skin or wounds from contamination, to decontaminate a site upon removal of previously applied compositions that provided a protective coating, and to inhibit the movement of bodily substances other than blood. The compositions are also useful in isolating tissue, removing tissue, preserving tissue (for, e.g., subsequent transplantation or reattachment), and as bulking, stabilizing or hydrating agents. Medical devices that include the compositions (e.g., a stent or catheter), bandages or other wound dressings, sutures, and kits that include the compositions are also described.Type: GrantFiled: August 27, 2008Date of Patent: June 14, 2016Assignees: Maasachusetts Institute of Technology, Versitech LimitedInventors: Rutledge Ellis-Behnke, Shuguang Zhang, Gerald Schneider, Kwok-Fai So, David Tay, Yu-Xiang Liang
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Patent number: 9327010Abstract: Compositions that include nanoscale structured materials or precursors thereof (e.g., self-assembling peptides) are described. The compositions can include other substances (e.g., a vasoconstrictor). Also described are methods for using the compositions to promote hemostasis, to protect the skin or wounds from contamination, to decontaminate a site upon removal of previously applied compositions that provided a protective coating, and to inhibit the movement of bodily substances other than blood. The compositions are also useful in isolating tissue, removing tissue, preserving tissue (for, e.g., subsequent transplantation or reattachment), and as bulking, stabilizing or hydrating agents. Medical devices that include the compositions (e.g., a stent or catheter), bandages or other wound dressings, sutures, and kits that include the compositions are also described.Type: GrantFiled: April 25, 2006Date of Patent: May 3, 2016Assignees: Massachusetts Institute of Technology, Versitech LimitedInventors: Rutledge Ellis-Behnke, Shuguang Zhang, Gerald Schneider, Kwok-Fai So, David Tay, Yu-Xiang Liang
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Publication number: 20150328279Abstract: Compositions which self-assemble under physiological conditions are formulated for application to wounds. The formulations include a pharmaceutically acceptable carrier or are provided as part of a medical device or coating. The formulations may also include other therapeutic, prophylactic or diagnostic agents. The formulation can be administered as appropriate for treatment of one or more disorders or conditions. For example, the formulation may be applied to repair an injury or during surgery of the lung, eye or dura, or following an epidural or spinal tap, to stop leakage of blood, interstitial fluid, or cerebrospinal fluid. The formulation may be administered to a burn or ulcer. The formulation may be dispersed in a suture or adhesive for administration at the time of or as released following suturing or gluing of a wound, thereby limiting bleeding, loss of tissue fluids, or other fluids such as those produced by parenchymal tissues such as the liver, pancreas, and gastrointestinal tract.Type: ApplicationFiled: June 23, 2015Publication date: November 19, 2015Applicants: Massachusetts Institute of Technology, Versitech LimitedInventors: Rutledge Ellis-Behnke, Yu-Xiang Liang, Gerald E. Schneider, Kwok-Fai So, David K.C. Tay
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Patent number: 9084837Abstract: Compositions which self-assemble under physiological conditions are formulated for application to wounds. The formulations include a pharmaceutically acceptable carrier or are provided as part of a medical device or coating. The formulations may also include other therapeutic, prophylactic or diagnostic agents. The formulation can be administered as appropriate for treatment of one or more disorders or conditions. For example, the formulation may be applied to repair an injury or during surgery of the lung, eye or dura, or following an epidural or spinal tap, to stop leakage of blood, interstitial fluid, or cerebrospinal fluid.Type: GrantFiled: April 25, 2007Date of Patent: July 21, 2015Assignees: Massachusetts Institute of Technology, Versitech Limited The University of Hong KongInventors: Rutledge Ellis-Behnke, Yu-Xiang Liang, Gerald E. Schneider, Kwok-Fai So, David Tay
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Publication number: 20090111734Abstract: Compositions that include nanoscale structured materials or precursors thereof (e.g., self-assembling peptides) are described. The compositions can include other substances (e.g., a vasoconstrictor). Also described are methods for using the compositions to promote hemostasis, to protect the skin or wounds from contamination, to decontaiminate a site upon removal of previously applied compositions that provided a protective coating, and to inhibit the movement of bodily substances other than blood. The compositions are also useful in isolating tissue, removing tissue, preserving tissue (for, e.g., subsequent transplantation or reattachment), and as bulking, stabilizing or hydrating agents. Medical devices that include the compositions (e.g., a stent or catheter), bandages or other wound dressings, sutures, and kits that include the compositions are also described.Type: ApplicationFiled: August 27, 2008Publication date: April 30, 2009Applicants: Massachusetts Institute of Technology, Versitech LimitedInventors: Rutledge Ellis-Behnke, Shuguang Zhang, Gerald Schneider, Kwok-Fai So, David Tay, Yu-Xiang Liang
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Publication number: 20080091233Abstract: Compositions which self-assemble under physiological conditions are formulated for application to wounds. The formulations include a pharmaceutically acceptable carrier or are provided as part of a medical device or coating. The formulations may also include other therapeutic, prophylactic or diagnostic agents. The formulation can be administered as appropriate for treatment of one or more disorders or conditions. For example, the formulation may be applied to repair an injury or during surgery of the lung, eye or dura, or following an epidural or spinal tap, to stop leakage of blood, interstitial fluid, or cerebrospinal fluid. The formulation may be administered to a burn or ulcer. The formulation may be dispersed in a suture or adhesive for administration at the time of or as released following suturing or gluing of a wound, thereby limiting bleeding, loss of tissue fluids, or other fluids such as those produced by parenchymal tissues such as the liver, pancreas, and gastrointestinal tract.Type: ApplicationFiled: April 25, 2007Publication date: April 17, 2008Applicant: Massachusetts Institute of TechnologyInventors: Rutledge Ellis-Behnke, Yu-Xiang Liang, Gerald Schneider, Kwok-Fai So, David Tay
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Publication number: 20070203062Abstract: Compositions that include nanoscale structured materials or precursors thereof (e.g., self-assembling peptides) are described. The compositions can include other substances (e.g., a vasoconstrictor). Also described are methods for using the compositions to promote hemostasis, to protect the skin or wounds from contamination, to decontaminate a site upon removal of previously applied compositions that provided a protective coating, and to inhibit the movement of bodily substances other than blood. The compositions are also useful in isolating tissue, removing tissue, preserving tissue (for, e.g., subsequent transplantation or reattachment), and as bulking, stabilizing or hydrating agents. Medical devices that include the compositions (e.g., a stent or catheter), bandages or other wound dressings, sutures, and kits that include the compositions are also described.Type: ApplicationFiled: April 25, 2006Publication date: August 30, 2007Inventors: Rutledge Ellis-Behnke, Shuguang Zhang, Gerald Schneider, Kwok-Fai So, David Tay, Yu-Xiang Liang