Abstract: Systems, apparatus, articles of manufacture, and methods are disclosed to preserve privacy in a user dataset including interface circuitry, machine readable instructions, and programmable circuitry to determine a data usage type for each one of a plurality of user data features in a first dataset, classify the data usage type associated with each user data feature of the plurality of user data feature into a feature category, apply at least one feature engineering mechanism to feature categories of the data usage types of the plurality of user data features, select, based on application of feature engineering, a subset of the plurality of user data features for a feature selection training model, and output a second dataset based on the subset of the plurality of user data for the feature selection training model, the second dataset to include fewer user data features than the first dataset.

Abstract: An acoustic monitoring system and method for the health status of an offshore wind turbine and an ocean wave are provided. The acoustic monitoring system includes a first laser transmitter, a second laser transmitter, a telephoto camera provided at a hub, a vibration detection sensor provided on a tower of a wind turbine, and four acoustic detection sensors arranged at an interval of 90° along the circumference of the tower. The first and second laser transmitters are arranged at the bottom of a nacelle of the wind turbine and emit laser lights vertically downward. The first laser transmitter, the second laser transmitter, the telephoto camera, the vibration detection sensor, and the acoustic detection sensors are connected to a data acquisition and conversion module through a transmission module. The acoustic monitoring system combines laser light detection with acoustic signal feature detection to improve stability and safety of the offshore wind turbine.

Abstract: An optical fiber connector includes a connecting unit, an adapter unit, and an attenuation unit. The adapter unit includes an insertion seat connected removably to a main housing of the connecting unit, and two guide frame bodies located respectively at two opposite sides of the insertion seat in a transverse direction. The insertion seat has two insertion holes spaced apart in the transverse direction and extending in a front-rear direction. Each guide frame body extends in the front-rear direction away from the connecting unit. The attenuation unit includes two attenuation components, two rear ferrules, and two front ferrules. The attenuation components are arranged in the transverse direction and disposed within the main housing. The rear ferrules respectively extend rearwardly from rear ends of the attenuation components into the insertion holes. The front ferrules respectively extend forwardly from front ends of the attenuation components through and outwardly of the main housing.

Abstract: Systems, apparatus, articles of manufacture, and methods are disclosed that include interface circuitry, machine readable instructions, and programmable circuitry to at least one of instantiate or execute the machine readable instructions to associate first datapoints of a first feature with a first node, associate second datapoints of a second feature with a second node, construct a graph from the first datapoints and the second datapoints, and perform a comparison of a graph accuracy with a baseline accuracy.

Abstract: Embodiments of the present disclosure relate to a method, device and computer readable storage medium of scene text detection. In the method, a first visual representation of a first image is generated with an image encoding process. A first textual representation of a first text unit in the first image is generated with a text encoding process based on a first plurality of symbols obtained by masking a first symbol of a plurality of symbols in the first text unit. A first prediction of the masked first symbol is determined with a decoding process based on the first visual and textual representations. At least the image encoding process is updating according to at least a first training objective to increase at least similarity of the first prediction and the masked first symbol.

Abstract: Embodiments of this application provide an information sending and receiving method and a communications device. The method includes: A network device configures first information. The first information includes a first field and/or a second field, the first field includes information indicating an energy saving state of a terminal device, and the second field includes information indicating a time length in which the terminal device maintains the energy saving state. Then, the network device sends the first information to the terminal device. In addition, the method includes: The terminal device receives the first information sent by the network device. Then, the terminal device reads the first field and/or the second field, and adjusts the energy saving state of the terminal device based on information obtained through reading. The technical solution provided in the embodiments of this application can reduce energy consumption of the terminal device to some extent.

Abstract: The present disclosure provides a method for processing defect information of a product, which includes the following steps of: acquiring defect information on a current film layer and defect information on historical film layers; determining whether defect information exists at a target location of the historical film layer if defect information exists at a target location of the current film layer; if defect information exists for a corresponding location to the target location in at least one of the historical film layers, deleting the defect information detected at the target location in the current film layer; and if no defect information exists for the target location in any of the historical film layers, retaining the defect information detected at the target location in the current film layer.

Abstract: An acoustic monitoring system and method for the health status of an offshore wind turbine and an ocean wave are provided. The acoustic monitoring system includes a first laser transmitter, a second laser transmitter, a telephoto camera provided at a hub, a vibration detection sensor provided on a tower of a wind turbine, and four acoustic detection sensors arranged at an interval of 90° along the circumference of the tower. The first and second laser transmitters are arranged at the bottom of a nacelle of the wind turbine and emit laser lights vertically downward. The first laser transmitter, the second laser transmitter, the telephoto camera, the vibration detection sensor, and the acoustic detection sensors are connected to a data acquisition and conversion module through a transmission module. The acoustic monitoring system combines laser light detection with acoustic signal feature detection to improve stability and safety of the offshore wind turbine.

Abstract: The present invention relates to a pyrimido[5,4-b]pyrrolizin compound represented by general formula I, an optical isomer thereof, a preparation method therefor, a pharmaceutical composition containing same, and a use thereof. The compound according to the present invention has good inhibitory activity on the kinase BTK at both the molecular level and the cellular level. Meanwhile, the compound also has good anti-tumor activity and pharmacokinetic properties in vivo.

Abstract: A method for a device to monitor performance of a manufacturing machine which is equipped with a fixture for holding a workpiece, the fixture having at least one fixing hole, includes obtaining actual coordinate values of the fixing hole in a plurality of machining processes and calculating a standard deviation of the coordinates in at least one axial direction according to the actual coordinate values and a preset standard coordinate value. A risk index in at least one axial direction is calculated according to the standard deviation and a preset tolerance and a determination made as to whether risk index exceeds a preset threshold. A warning is sent to the machine and supervising engineer if the risk exceeds the preset threshold. A machine monitoring device and a computer readable storage medium are also provided.

Abstract: A method for a device to monitor performance of a manufacturing machine which is equipped with a fixture for holding a workpiece, the fixture having at least one fixing hole, includes obtaining actual coordinate values of the fixing hole in a plurality of machining processes and calculating a standard deviation of the coordinates in at least one axial direction according to the actual coordinate values and a preset standard coordinate value. A risk index in at least one axial direction is calculated according to the standard deviation and a preset tolerance and a determination made as to whether risk index exceeds a preset threshold. A warning is sent to the machine and supervising engineer if the risk exceeds the preset threshold. A machine monitoring device and a computer readable storage medium are also provided.

Abstract: The present disclosure relates to a Pyrimido[5,4-b]indolizine or pyrimido[5,4-b]pyrrolizine compound, preparation method thereof and use thereof. The compounds of the present invention have good inhibitory activities against BTK at the molecular and cellular levels. Importantly, the compounds of the present invention have low activity against Ramos cells of normal human B lymphoma cells, and have high activity against BTK-sensitive human diffuse large B lymphoma TMD8 cells, indicating that these type of compounds with novel structural are highly selective, off-target phenomenon and corresponding side effects are low. Thus it is a selective inhibitor of BTK with development potential.

Abstract: The present disclosure relates to a Pyrimido[5,4-b]indolizine or pyrimido[5,4-b]pyrrolizine compound, preparation method thereof and use thereof. The compounds of the present invention have good inhibitory activities against BTK at the molecular and cellular levels. Importantly, the compounds of the present invention have low activity against Ramos cells of normal human B lymphoma cells, and have high activity against BTK-sensitive human diffuse large B lymphoma TMD8 cells, indicating that these type of compounds with novel structural are highly selective, off-target phenomenon and corresponding side effects are low. Thus it is a selective inhibitor of BTK with development potential.

Abstract: Antigen binding proteins which bind to human IL-7 receptor (CD127) are provided. The antigen binding proteins are typically antibodies, and are useful in the treatment of diseases or disorders in humans, particularly autoimmune diseases such as multiple sclerosis.

Abstract: The present disclosure relates to antigen binding proteins, such as antibodies, that bind to HER3, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. The present disclosure also concerns the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with breast cancer, ovarian cancer, prostate cancer, bladder cancer, pancreatic, gastric, melanoma and other cancers that overexpress HER3.

Abstract: Antigen binding proteins which bind to human IL-7 receptor (CD127) are provided. The antigen binding proteins are typically antibodies, and are useful in the treatment of diseases or disorders in humans, particularly autoimmune diseases such as multiple sclerosis.

Abstract: The present disclosure relates to antigen binding proteins, such as antibodies, that bind to HER3, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. The present disclosure also concerns the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with breast cancer, ovarian cancer, prostate cancer, bladder cancer, pancreatic, gastric, melanoma and other cancers that overexpress HER3.

Abstract: Antigen binding proteins which bind to human IL-7 receptor (CD127) are provided. The antigen binding proteins are typically antibodies, and are useful in the treatment of diseases or disorders in humans, particularly autoimmune diseases such as multiple sclerosis.

Abstract: Antigen binding proteins which bind to human IL-7 receptor (CD127) are provided. The antigen binding proteins are typically antibodies, and are useful in the treatment of diseases or disorders in humans, particularly autoimmune diseases such as multiple sclerosis.

Abstract: A process is provided for the semi-synthesis of taxane derivatives useful in the preparation of docetaxel, in particular, the semi-synthesis of protected taxane derivatives in a one pot reaction of protecting the C-2?, C-7 and C-10 and introducing a t-Boc group at the nitrogen of the amide group at the C-3? position in paclitaxel and subsequently conversion to docetaxel, and derivatives used therein.