Patents by Inventor Yu-Yawn Chen

Yu-Yawn Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating leukemia using rice prolamin
    Patent number: 9333236
    Abstract: The present invention relates to a method of treating leukemia using rice prolamin, comprising administering a daily dose of isolated prolamin to a patient suffering from leukemia for a period of time from 5 days to 10 days. For the treatment application, the rice prolamin can stimulate human peripheral blood mononuclear cell (PBMC) to produce cytokines, such as tumor necrosis factor-alpha, to inhibit growth of and induce differentiation of human leukemia cells. The rice prolamin is gluten-free, thus will not trigger gastrointestinal allergic reaction, it also can decrease the tumor weight without changes in body weight and can inhibit the growth of peripheral blood leukocyte in leukemia mouse model.
    Type: Grant
    Filed: October 31, 2014
    Date of Patent: May 10, 2016
    Assignee: MACKAY MEMORIAL HOSPITAL
    Inventors: Yu-Jen Chen, Hui-Fen Liao, Yu-Yawn Chen
  • METHOD OF TREATING LEUKEMIA USING RICE PROLAMIN
    Publication number: 20150051156
    Abstract: The present invention relates to a method of treating leukemia using rice prolamin, comprising administering a daily dose of isolated prolamin to a patient suffering from leukemia for a period of time from 5 days to 10 days. For the treatment application, the rice prolamin can stimulate human peripheral blood mononuclear cell (PBMC) to produce cytokines, such as tumor necrosis factor-alpha, to inhibit growth of and induce differentiation of human leukemia cells. The rice prolamin is gluten-free, thus will not trigger gastrointestinal allergic reaction, it also can decrease the tumor weight without changes in body weight and can inhibit the growth of peripheral blood leukocyte in leukemia mouse model.
    Type: Application
    Filed: October 31, 2014
    Publication date: February 19, 2015
    Inventors: Yu-Jen Chen, Hui-Fen Liao, Yu-Yawn Chen
  • Method of Treating Leukemia Using Rcie Prolamin
    Publication number: 20110183918
    Abstract: The present invention relates to a method of treating leukemia using rice prolamin, and a pharmaceutical composition for treating leukemia, comprising an effective amount of rice prolamin together with one or more pharmaceutically acceptable carriers or excipients. For the treatment application, the rice prolamin can stimulate human peripheral blood mononuclear cell (PBMC) to produce cytokines, such as tumor necrosis factor-alpha, to inhibit growth of and induce differentiation of human leukemia U937 cells. The rice prolamin is gluten-free, thus will not trigger gastrointestinal allergic reaction.
    Type: Application
    Filed: July 28, 2010
    Publication date: July 28, 2011
    Applicant: MACKAY MEMORIAL HOSPITAL
    Inventors: Yu-Jen Chen, Hui-Fen Liao, Yu-Yawn Chen