Abstract: The present invention relates to a method for producing recombinant human prethrombin-2 protein and having human ?-thrombin activity by the plant-based expression systems.

Abstract: A power conversion apparatus supplies power to a load, and the power conversion apparatus includes a power switch, a transformer, and a control module. The control module alternately turns on and turns off a power switch of the power conversion apparatus to convert an input voltage into an output voltage through the transformer. When the power switch is turned off, a primary side of the transformer generates a resonance voltage. The control module sets a predetermined counting threshold according to the output voltage, and sets a blanking time interval according to a feedback signal related to the load. After the blanking time interval ends, the control module counts a number of an oscillation turning point generated by the resonance voltage due to the oscillation of the resonance voltage. When the number reaches the predetermined counting threshold, the control module turns on the power switch.

Abstract: In an embodiment, an interposer has a first side, a first integrated circuit device attached to the first side of the interposer with a first set of conductive connectors, each of the first set of conductive connectors having a first height, a first die package attached to the first side of the interposer with a second set of conductive connectors, the second set of conductive connectors including a first conductive connector and a second conductive connector, the first conductive connector having a second height, the second conductive connector having a third height, the third height being different than the second height, a first dummy conductive connector being between the first side of the interposer and the first die package, an underfill disposed beneath the first integrated circuit device and the first die package, and an encapsulant disposed around the first integrated circuit device and the first die package.

Abstract: A synchronized rectification control method for use in a flyback converter is provided. The flyback converter includes a transformer including a secondary winding, a synchronous rectifier switch and a synchronous rectifier controller. The synchronous rectifier switch is coupled to the secondary winding and the synchronous rectifier controller, and is used to output a voltage difference signal and receive a control voltage. The method includes the synchronous rectifier controller detecting a rapid falling edge of the voltage difference signal to generate a rapid falling edge signal, generating an envelope signal according to the voltage difference signal, generating a time length control signal according to the voltage difference signal and the envelope signal, generating a blanking time signal according to the voltage difference signal and the time length control signal, and performing a logic operation on the blanking time signal and the rapid falling edge signal to generate the control voltage.

Abstract: A power controller with short-circuit protection is disclosed to control a power switch, which is connected in series with a current-sense resistor and an inductive device between two power lines. The current-sense resistor provides a current-sense signal. The power controller includes a PWM signal generator and a short-circuit protection circuit. The PWM signal generator generates a PWM signal to the power switch to create switching cycles, each consisting of an ON time and an OFF time. The short-circuit protection circuit has a high-pass filter and a condition detector. The high-pass filter high-pass filters the current-sense signal to provide a filtered signal to the condition detector, which determines whether the filtered signal fits a predetermined condition during the ON time to generate a short-circuit protection signal and to prevent the power switch being turned on.

Abstract: A synchronous rectifier controller for controlling a rectifier switch is disclosed. The synchronous rectifier controller includes a fully-ON controller and a regulator. Capable of being triggered by a channel voltage of the rectifier switch, the fully-ON controller turns the rectifier switch fully ON for a fully-ON time in view of a predetermined condition. The regulator, disabled during the fully-ON time and enabled after the fully-ON time, turns the rectifier switch ON to regulate the channel voltage within a predetermined voltage range.

Abstract: A package assembly includes a package substrate including a first die that includes a photonic integrated circuit, a second die located on the first die, the second die including an electronic integrated circuit electrically connected to the photonic integrated circuit, and an interposer module on the package substrate, at least a portion of the interposer module being located on the first die and electrically connected to the photonic integrated circuit.

Abstract: A filter capacitor discharge circuit includes a high-voltage terminal, a signal preparation circuit, a low-pass filter, a voltage level detector, a timer unit, and a switch unit. The signal preparation circuit receives a detection signal corresponding to an AC voltage from the high-voltage terminal, and generates a voltage signal according to the detection signal. The low-pass filter provides a filtered signal according to the voltage signal. The voltage level detector checks whether a voltage difference between the voltage signal and the filtered signal is less than a predetermined value. When the voltage difference is less than the predetermined value, the timer unit performs time calculation to accumulate a timing result. When the timing result exceeds a predetermined time, the switch unit is turned on so that the firster capacitor is discharged through the switch unit.

Abstract: In an embodiment, an interposer has a first side, a first integrated circuit device attached to the first side of the interposer with a first set of conductive connectors, each of the first set of conductive connectors having a first height, a first die package attached to the first side of the interposer with a second set of conductive connectors, the second set of conductive connectors including a first conductive connector and a second conductive connector, the first conductive connector having a second height, the second conductive connector having a third height, the third height being different than the second height, a first dummy conductive connector being between the first side of the interposer and the first die package, an underfill disposed beneath the first integrated circuit device and the first die package, and an encapsulant disposed around the first integrated circuit device and the first die package.

Abstract: A power controller with short-circuit protection is disclosed to control a power switch, which is connected in series with a current-sense resistor and an inductive device between two power lines. The current-sense resistor provides a current-sense signal. The power controller includes a PWM signal generator and a short-circuit protection circuit. The PWM signal generator generates a PWM signal to the power switch to create switching cycles, each consisting of an ON time and an OFF time. The short-circuit protection circuit has a high-pass filter and a condition detector. The high-pass filter high-pass filters the current-sense signal to provide a filtered signal to the condition detector, which determines whether the filtered signal fits a predetermined condition during the ON time to generate a short-circuit protection signal and to prevent the power switch being turned on.

Abstract: A filter capacitor discharge circuit includes a high-voltage terminal, a signal preparation circuit, a low-pass filter, a voltage level detector, a timer unit, and a switch unit. The signal preparation circuit receives a detection signal corresponding to an AC voltage from the high-voltage terminal, and generates a voltage signal according to the detection signal. The low-pass filter provides a filtered signal according to the voltage signal. The voltage level detector checks whether a voltage difference between the voltage signal and the filtered signal is less than a predetermined value. When the voltage difference is less than the predetermined value, the timer unit performs time calculation to accumulate a timing result. When the timing result exceeds a predetermined time, the switch unit is turned on so that the firster capacitor is discharged through the switch unit.

Abstract: A power conversion apparatus supplies power to a load, and the power conversion apparatus includes a power switch, a transformer, and a control module. The control module alternately turns on and turns off a power switch of the power conversion apparatus to convert an input voltage into an output voltage through the transformer. When the power switch is turned off, a primary side of the transformer generates a resonance voltage. The control module sets a predetermined counting threshold according to the output voltage, and sets a blanking time interval according to a feedback signal related to the load. After the blanking time interval ends, the control module counts a number of an oscillation turning point generated by the resonance voltage due to the oscillation of the resonance voltage. When the number reaches the predetermined counting threshold, the control module turns on the power switch.

Abstract: A synchronous rectifier controller for controlling a rectifier switch is disclosed. The synchronous rectifier controller includes a fully-ON controller and a regulator. Capable of being triggered by a channel voltage of the rectifier switch, the fully-ON controller turns the rectifier switch fully ON for a fully-ON time in view of a predetermined condition. The regulator, disabled during the fully-ON time and enabled after the fully-ON time, turns the rectifier switch ON to regulate the channel voltage within a predetermined voltage range.

Abstract: A power converter capable of performing over-voltage protection and over-temperature protection converts an input voltage into an output voltage. A power switch is connected in series with a primary winding between the input voltage and an input ground. A power controller with a multi-function pin controls the power switch to control a winding current through the primary winding. The power converter has a multi-purpose circuit with first and second resistors, a rectifier and a thermistor. A connection node makes the first and second resistors connected in series between two ends of an auxiliary winding. The rectifier and the thermistor are connected in parallel between the multi-function pin and the connection node. The power controller can perform over-voltage protection and over-temperature protection via the multi-purpose circuit and the multi-function pin.

Abstract: A power converter capable of performing over-voltage protection and over-temperature protection converts an input voltage into an output voltage. A power switch is connected in series with a primary winding between the input voltage and an input ground. A power controller with a multi-function pin controls the power switch to control a winding current through the primary winding. The power converter has a multi-purpose circuit with first and second resistors, a rectifier and a thermistor. A connection node makes the first and second resistors connected in series between two ends of an auxiliary winding. The rectifier and the thermistor are connected in parallel between the multi-function pin and the connection node. The power controller can perform over-voltage protection and over-temperature protection via the multi-purpose circuit and the multi-function pin.

Abstract: A controller for generating jitters in a quasi resonant mode includes a feedback pin, a voltage generation unit, a pulse generator, and a comparator. The feedback pin is used for receiving a feedback voltage from a secondary side of a power converter. The voltage generation unit is used for generating a first voltage according to the feedback voltage and a pulse. The pulse generator is used for generating the pulse when a control signal controlling a power switch of a primary side of the power converter is enabled. The comparator is used for controlling enabling and disabling of a switching signal according to the first voltage and a variable reference voltage. The variable reference voltage is monotonously swung within a predetermined range according to a digital signal.

Abstract: A power supply has an inductor and determines loading state of the power supply according to a compensation signal. When the loading state is determined to be a light loading state or a no-loading state, a switch is operated at a low operating frequency. When the loading state is determined to be a heavy loading state, the switch is operated at a high operating frequency. If the compensation signal exceeds a critical value, it is determined that the loading state is an overloaded state. When the overloaded state continues past a tolerable duration, the switch is turned off. The tolerable duration is determined by an external capacitor and is independent of the operating frequency.

Abstract: A controller for generating jitters in a constant current mode of a power converter includes a current pin, an auxiliary pin, a constant current control unit, and a control signal generation unit. The current pin is used for receiving a primary side voltage determined according to a resistor and a primary side current flowing through the power converter. The auxiliary pin is used for receiving a voltage corresponding to an auxiliary winding of the power converter. The constant current control unit is used for generating an adjustment signal according to the primary side voltage, a discharge time corresponding to the voltage, and a reference voltage. The reference voltage has a predetermined range jitter voltage. The control signal generation unit is used for adjusting a period of a gate control signal according to the adjustment signal.

Abstract: Power controllers and related primary-side control methods are disclosed. A disclosed power controller has a comparator and an ON-triggering controller. The comparator compares a feedback voltage with an over-shot reference voltage. Based on an inductance-coupling effect, the feedback voltage represents a secondary-side voltage of a secondary winding. Coupled to the comparator, the ON-triggering controller operates a power switch at about a first switching frequency when the feedback voltage is lower than the over-shot reference voltage. The ON-triggering controller operates the power switch at about a second switching frequency when the feedback voltage exceeds the over-shot reference voltage. The second switching frequency is less than the first switching frequency.

Abstract: Power controllers and related primary-side control methods are disclosed. A disclosed power controller has a comparator and an ON-triggering controller. The comparator compares a feedback voltage with an over-shot reference voltage. Based on an inductance-coupling effect, the feedback voltage represents a secondary-side voltage of a secondary winding. Coupled to the comparator, the ON-triggering controller operates a power switch at about a first switching frequency when the feedback voltage is lower than the over-shot reference voltage. The ON-triggering controller operates the power switch at about a second switching frequency when the feedback voltage exceeds the over-shot reference voltage. The second switching frequency is less than the first switching frequency.