Patents by Inventor Yu Zhuang

Yu Zhuang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250122257
    Abstract: Provided is use of kinin or derivative thereof, in particular long-acting kinin or derivative thereof, in treating vascular cognitive impairment (VCI), post-stroke cognitive impairment (PSCI), or cerebral small vessel disease (CSVD). VCI and PSCI are generally associated with cognitive function impairment and psychoactive behavioral symptom. Drugs for treating cognitive impairment in VCI and PSCI include cholinesterase inhibitors, non-competitive N-methyl-D-asparagine receptor antagonists, and drugs for treating psychoactive behavioral symptom include antidepressants. Patients with chronic CSVD may have symptoms such as cognitive disorder, movement disorder, emotional disorder, defecation disorder and other symptoms. Cholinesterase inhibitors and non-competitive N-methyl-D-asparagine receptor antagonists can be used for cognitive disorder, and antidepressants are generally used for depression.
    Type: Application
    Filed: January 17, 2023
    Publication date: April 17, 2025
    Inventors: Bruce Yong MA, Chenyang JIANG, Yu ZHUANG, Zhen XU, Dan XU, Jun WANG
  • Publication number: 20250123891
    Abstract: The embodiments of the present disclosure provide a resource processing method, a resource scheduling method, a computing device and a computer storage medium, where the resource processing method includes: creating, according to the number of a pod needed by a target application, at least one instance corresponding to the number of the pod for the target application; performing, according to a resource requirement parameter of the at least one instance and respective available resources of multiple nodes respectively, simulation scheduling in the multiple nodes to determine at least one target node and a respective reserved resource thereof; and generating, according to a simulation scheduling result, a resource reservation result of the target application, where the resource reservation result is used to instruct to perform resource scheduling for the target application by using the a reserved resource of the at least one target node.
    Type: Application
    Filed: February 13, 2023
    Publication date: April 17, 2025
    Inventors: Yu ZHUANG, Shuangkun TIAN, Qingcan WANG, Peng LI, Kai ZHANG
  • Publication number: 20250109176
    Abstract: A recombinant type I allergen of Artemisia annua pollen (Art a 1), a coding gene, an expression method, and a purification method thereof are provided. By different combinations of codon optimization, different signal peptides, expression vectors and strains, the Art a 1 obtained reaches the expression level of more than 200 mg/L, with a purity of more than 99%, and the activity of the Art a 1 is equivalent to that of a native protein, and the Art a 1 can be used for the desensitization immunotherapy and diagnosis of Artemisia pollen allergy.
    Type: Application
    Filed: December 30, 2022
    Publication date: April 3, 2025
    Applicant: ZONHON BIOPHARMA INSTITUTE, INC.
    Inventors: Bruce Yong MA, Baixue ZHAO, Hui GAO, Yu ZHUANG, Qin WANG
  • Publication number: 20250066432
    Abstract: A recombinant type I allergen of Artemisia vulgaris pollen (Art v 1), a coding gene, an expression method, and a purification method thereof are provided. By different combinations of codon optimization, different signal peptides, expression vectors and strains, the Art v 1 obtained reaches the expression level of more than 200 mg/L, with a purity of more than 99%, and the activity of the Art v 1 is equivalent to that of a native protein, and the Art v 1 can be used for the desensitization immunotherapy and diagnosis of Artemisia pollen allergy.
    Type: Application
    Filed: December 30, 2022
    Publication date: February 27, 2025
    Applicant: ZONHON BIOPHARMA INSTITUTE, INC.
    Inventors: Bruce Yong MA, Baixue ZHAO, Hui GAO, Yu ZHUANG, Qin WANG
  • Publication number: 20250011747
    Abstract: Provided are low glycosylated kallikrein I with no or a small amount of glycosylation at the NFS sequence and polyethylene glycol modified product and pharmaceutical applications. KLK1 with lower glycosylation at NFS is more active than KLK1 with higher glycosylation at NFS. A recombinant KLK1 mutant without N-glycosylation at the NFS sequence is also provided, containing only two N-glycosylation sites at NMS and NHT. Glycosylation of the recombinant KLK1 mutant is relatively more consistent, the molecular weight of the product is relatively more homogeneous, the yield is higher, the purification process is simpler, and the biological activity is higher, and the quality is more controllable.
    Type: Application
    Filed: November 16, 2022
    Publication date: January 9, 2025
    Inventors: Bruce Yong MA, He WANG, Jun WANG, Chennan GE, Chenyang JIANG, Xiang YAO, Fang SUN, Tao ZHANG, Yu ZHUANG, Menghan ZHANG
  • Publication number: 20240276666
    Abstract: Top-mount PCB mounting assemblies, and electronic devices and optical communication device thereof are provided. The top-mount PCB mounting assemblies may include a PCB with a top surface as a reference surface; a chassis disposed underneath the PCB and separate from the PCB; a shoulder screw comprising a screw head, a screw body and a screw tail, where the shoulder screw is soldered on a top of the PCB and is connected to the chassis by tightening a M2.5 screw from a bottom of the chassis; and a nut, positioned between the PCB and the chassis, made of a rigid feature, and configured to receive and fasten the shoulder screw and keep a distance between the PCB and the chassis within a controlled dimension.
    Type: Application
    Filed: January 28, 2024
    Publication date: August 15, 2024
    Inventors: Glenn Lee, Lily Yu Zhuang
  • Patent number: 11372707
    Abstract: An approach is provided in which a set of provision information is generated from a set of provisioners that are in process of fulfilling a client's provision request. The approach creates a set of provision events based on the set of provision information and, in response to detecting a failure of the provision request, the approach generates a provision chain from the set of provision events. The provision chain links the set of provision events based on correlation rules and identifies at least one isolation point of the failure. The approach informs the client of the at least one isolation point of the failure identified in the provision chain.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: June 28, 2022
    Assignee: International Business Machines Corporation
    Inventors: Yu Zhuang, Bo Chen Zhu, Xu Liu, Jun Su, Xu Bin Liu
  • Publication number: 20210248022
    Abstract: An approach is provided in which a set of provision information is generated from a set of provisioners that are in process of fulfilling a client's provision request. The approach creates a set of provision events based on the set of provision information and, in response to detecting a failure of the provision request, the approach generates a provision chain from the set of provision events. The provision chain links the set of provision events based on correlation rules and identifies at least one isolation point of the failure. The approach informs the client of the at least one isolation point of the failure identified in the provision chain.
    Type: Application
    Filed: February 6, 2020
    Publication date: August 12, 2021
    Inventors: Yu Zhuang, Bo Chen Zhu, Xu Liu, Jun Su, Xu Bin Liu
  • Patent number: 10901698
    Abstract: Embodiments of the present disclosure relate to a computer-implemented method for executing one or more operations based on a command. According to the method, a command is received. A command name of the command and one or more parameters of the command are extracted. A command description file corresponding to the command is retrieved based on the command name. The command description file describes function logic of the command. The retrieved command description file is parsed, and information for executing one or more operations included in the command description file is acquired. The one or more operations are executed based on the acquired information and the one or more parameters.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: January 26, 2021
    Assignee: International Business Machines Corporation
    Inventors: Kun Yang, Jun Li Wang, Yu Zhuang, Hongling Zhang
  • Publication number: 20200174754
    Abstract: Embodiments of the present disclosure relate to a computer-implemented method for executing a command. According to the method, a command is received. A command name of the command and one or more parameters of the command are extracted. A command description file corresponding to the command is retrieved based on the command name. The command description file describes function logic of the command. Information for executing one or more operations included in the command description file is acquired by parsing the retrieved command description file. The one or more operations are executed based on the acquired information and the one or more parameters.
    Type: Application
    Filed: November 30, 2018
    Publication date: June 4, 2020
    Inventors: Kun Yang, Jun Li Wang, Yu Zhuang, Hongling Zhang
  • Patent number: 10038615
    Abstract: A data storage system stores historical statistical data in a statistics hierarchy that is a tree of nodes. The data storage system receives a metric request from a remote requesting device through a Representational State Transfer (RESTful) Application Programming Interface (API), including a metric path that is a delimited list of list elements separated by delimiter characters. In response to an aggregation special character in the metric path, the data storage system i) obtains a category name immediately preceding the aggregation special character in the metric path, ii) identifies a branch of the statistics hierarchy indicated by the category name, iii) aggregates values of leaf nodes contained in the branch of the statistics hierarchy indicated by the category name that match a leaf type in the metric path to generate an aggregated value, and iv) transmits a metric response containing the aggregated value to the remote requesting device.
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: July 31, 2018
    Assignee: EMC IP Holding Company LLC
    Inventors: Pei Yu Zhuang, Amr H. Mohamed
  • Patent number: 9709767
    Abstract: Methods, systems, and apparatus for optical communications. One of the apparatuses includes a spool comprising a spool wheel, one or more separate spool portions positioned on the spool wheel, and one or more bearings positioned on the spool wheel, wherein the one or more spool portions and the one or more bearings are configured such that an optical fiber ribbon can be wound through the spool; and a spring coupled to the spool wheel such that the spring provides a rotational force on the spool in a direction that winds the optical fiber ribbon.
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: July 18, 2017
    Assignee: Oplink Communications, LLC
    Inventors: Lily Yu Zhuang, Qinhan Li
  • Patent number: 9590999
    Abstract: Embodiments relate to preview serving of content previews from a preview service for a component having associated content. A filter of a layered preview service executing on a processor receives a request from a client consumer for a feed from the component. The filter identifies a content reference returned by the component in response to the request for the feed. The filter establishes an association between the content reference and a user identifier of the client consumer as an authorization record. A preview service receives a preview request including the user identifier and a content identifier. The authorization record is checked to determine whether the content identifier matches the content reference for the user identifier. A content preview of the associated content as identified by the content identifier is served based on determining that a match exists.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: March 7, 2017
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Jonathan F. Brunn, Sheng Hu, Bo Min Nie, Yu Zhuang
  • Patent number: 9548555
    Abstract: A cable connector assembly including: a cable including a number of core wires, each core wire including an insulative layer and an inner conductor; and an electrical connector connected with an end of the cable, the electrical connector including an insulative housing, a number of contacts retained in the insulative housing, a shell member enclosing the insulative housing, a cover member assembled on a rear end of the insulative housing for fixing the core wires, and a carrying member connected between the cover member and the insulative housing, each of the contacts including a mounting portion rearwardly exposed to the insulative housing, wherein each of the mounting portion defines a spines portion, the cover member defines a number of through holes receiving the core wires, and the insulative layer of the core wire is punctured by the spines portion when the cover member is mounted on the carrying member.
    Type: Grant
    Filed: March 28, 2016
    Date of Patent: January 17, 2017
    Assignee: FOXCONN INTERCONNECT TECHNOLOGY LIMITED
    Inventors: Fei Guo, Xu-Xiang Qi, Cai-Yu Zhuang, Yang-Tsun Hsu, Chao-Ling Wang
  • Publication number: 20160285882
    Abstract: Embodiments relate to preview serving of content previews from a preview service for a component having associated content. A filter of a layered preview service executing on a processor receives a request from a client consumer for a feed from the component. The filter identifies a content reference returned by the component in response to the request for the feed. The filter establishes an association between the content reference and a user identifier of the client consumer as an authorization record. A preview service receives a preview request including the user identifier and a content identifier. The authorization record is checked to determine whether the content identifier matches the content reference for the user identifier. A content preview of the associated content as identified by the content identifier is served based on determining that a match exists.
    Type: Application
    Filed: March 25, 2015
    Publication date: September 29, 2016
    Inventors: Jonathan F. Brunn, Sheng Hu, Bo Min Nie, Yu Zhuang
  • Publication number: 20160285190
    Abstract: A cable connector assembly including: a cable including a number of core wires, each core wire including an insulative layer and an inner conductor; and an electrical connector connected with an end of the cable, the electrical connector including an insulative housing, a number of contacts retained in the insulative housing, a shell member enclosing the insulative housing, a cover member assembled on a rear end of the insulative housing for fixing the core wires, and a carrying member connected between the cover member and the insulative housing, each of the contacts including a mounting portion rearwardly exposed to the insulative housing, wherein each of the mounting portion defines a spines portion, the cover member defines a number of through holes receiving the core wires, and the insulative layer of the core wire is punctured by the spines portion when the cover member is mounted on the carrying member.
    Type: Application
    Filed: March 28, 2016
    Publication date: September 29, 2016
    Inventors: FEI GUO, XU-XIANG QI, CAI-YU ZHUANG, YANG-TSUN HSU, CHAO-LING WANG
  • Publication number: 20150131959
    Abstract: Methods, systems, and apparatus for optical communications. One of the apparatuses includes a spool comprising a spool wheel, one or more separate spool portions positioned on the spool wheel, and one or more bearings positioned on the spool wheel, wherein the one or more spool portions and the one or more bearings are configured such that an optical fiber ribbon can be wound through the spool; and a spring coupled to the spool wheel such that the spring provides a rotational force on the spool in a direction that winds the optical fiber ribbon.
    Type: Application
    Filed: November 10, 2014
    Publication date: May 14, 2015
    Inventors: Lily Yu Zhuang, Qinhan Li
  • Patent number: 7843263
    Abstract: A power amplifier with noise shaping function is provided. The power amplifier includes a differential mode integrator, an integration and adjustment unit and a switch unit. The differential mode integrator is used for receiving a differential mode input signal and a differential mode output signal, and outputting a differential mode first signal. The integration and adjustment unit is coupled to the differential mode integrator for receiving the first signal and an output signal and outputting a single-end mode second signal. The switch unit is used for receiving the second signal and outputting the differential mode output signal to drive the load. The present invention uses a common mode input signal instead of the single-end input signal to eliminate the common mode noise, and uses a 2nd-order (or more than that) integrating circuit instead of the conventional filter to achieve a preferred effect of reducing the off band noise.
    Type: Grant
    Filed: June 8, 2007
    Date of Patent: November 30, 2010
    Assignee: Himax Analogic, Inc.
    Inventors: Kuo-Hung Wu, Jun-Nian Lin, Zhi-Yu Zhuang
  • Publication number: 20080303590
    Abstract: A power amplifier with noise shaping function is provided. The power amplifier includes a differential mode integrator, an integration and adjustment unit and a switch unit. The differential mode integrator is used for receiving a differential mode input signal and a differential mode output signal, and outputting a differential mode first signal. The integration and adjustment unit is coupled to the differential mode integrator for receiving the first signal and an output signal and outputting a single-end mode second signal. The switch unit is used for receiving the second signal and outputting the differential mode output signal to drive the load. The present invention uses a common mode input signal instead of the single-end input signal to eliminate the common mode noise, and uses a 2nd-order (or more than that) integrating circuit instead of the conventional filter to achieve a preferred effect of reducing the off band noise.
    Type: Application
    Filed: June 8, 2007
    Publication date: December 11, 2008
    Applicant: HIMAX ANALOGIC, INC.
    Inventors: Kuo-Hung Wu, Jun-Nian Lin, Zhi-Yu Zhuang