Abstract: Provided are a lipid compound, a composition containing the same and use. The lipid compound is prepared by a ring-opening reaction of an organic amine and glycidyl ester and does not structurally contain free amino. The lipid compound can be ionized into a cationic compound under acidic conditions and is bonded to a negatively charged active pharmaceutical ingredient through electrostatic interaction, thereby being assembled into a drug-loaded lipid nanoparticle for delivery of the active pharmaceutical ingredient. The lipid compound provided by the present invention has a simple structure, a simple reaction path and a high yield. The constructed drug-loaded lipid nanoparticle can be used for preparing nucleic acid drugs, genetic vaccines, polypeptide or protein drugs, and small molecule drugs, and has a broad application prospect.

Abstract: A static voltage stability margin evaluation method and system, and a terminal device are related to the field of integrated energy system operation. The method includes the following steps: establishing a thermal dynamic model of a heating system; establishing a thermoelectric coupling device model; establishing a static voltage stability margin model of an electric power system that considers thermal dynamics of the heating system; and solving the model to obtain a voltage stability margin. In the present invention, a static voltage stability margin that considers thermal dynamics of a heating system can be obtained, and a Pareto boundary of the static voltage stability margin that considers the thermal dynamics can be obtained through a dual-objective nonlinear optimization method, so that an impact of thermoelectric coupling on voltage stability and an impact of thermal inertia of the heating system on a voltage stability margin can be revealed.

Abstract: A selenium-chelating pea oligopeptide, a preparation method thereof and use thereof. After the selenium-chelating pea oligopeptide is subjected to digestion treatment in at least one of following three ways, a change rate of selenium content not more than 3% with respect to the selenium content before the digestion treatment: hydrolyzing for 4 hours by a pepsin at a pH value of 2 and a temperature of 37° C.; hydrolyzing for 6 hours by a trypsin at a pH value of 7.5 and a temperature of 37° C.; maintaining the temperature constant at 37° C., firstly hydrolyzing for 4 hours by the pepsin at a pH value of 2, and then continuing to hydrolyze for 6 hours by a trypsin at a pH value of 6.8. The preparation method thereof includes mixing and reacting an aqueous solution of pea oligopeptide and sodium selenite, and then being subjected to alcohol precipitation and drying.

Abstract: a patch antenna structure includes: a dielectric substrate, having a first surface and a second surface that face away from each other; a metal ground layer, attached to the first surface of the dielectric substrate and provided with a plurality of slots; and an array of antenna elements, composed of four antenna elements and disposed on the second surface of the dielectric substrate; wherein in the array of antenna elements, a spacing between centers of two adjacent antenna elements in a same row is less than a predetermined standard distance, and antenna elements in adjacent rows are arranged to mirror each other. The embodiments of the present disclosure are simple in structure and are applicable to various scenarios of indoor ultra-wideband base stations.

Abstract: A method of performing synchronous replication from a primary storage system apparatus (PSSA) to a secondary storage system apparatus (SSSA) is provided. The method includes (a) in response to write requests received by the PSSA, (i) calculating metadata changes by the PSSA for accommodating the write requests, (ii) generating, by the PSSA, metadata journal log entries that describe the metadata changes, and (iii) mirroring the metadata journal log entries from the PSSA to the SSSA; (b) regenerating the metadata changes by the SSSA based on the metadata journal log entries mirrored from the PSSA to the SSSA; and (c) writing the regenerated metadata changes to persistent storage of the SSSA. A method performed by the SSSA is also provided. An apparatus, system, and computer program product for performing similar methods are also provided.

Abstract: Techniques for data replication involve: in response to a first source state machine associated with a source file system being booted up, booting up a second source state machine associated with the source file system, the first source state machine performing a first operation for resizing a first storage area of data for replication from the source file system; transmitting a resizing message from the second source state machine to a destination file system, to enable the destination file system to perform a second operation for resizing a second storage area for storing the data to be replicated into the destination file system; and in response to the first operation and the second operation being successfully performed, enabling the data for replication from the source file system to be replicated into the destination file system.

Abstract: A method of performing synchronous replication from a primary storage system apparatus (PSSA) to a secondary storage system apparatus (SSSA) is provided. The method includes (a) in response to write requests received by the PSSA, (i) calculating metadata changes by the PSSA for accommodating the write requests, (ii) generating, by the PSSA, metadata journal log entries that describe the metadata changes, and (iii) mirroring the metadata journal log entries from the PSSA to the SSSA; (b) regenerating the metadata changes by the SSSA based on the metadata journal log entries mirrored from the PSSA to the SSSA; and (c) writing the regenerated metadata changes to persistent storage of the SSSA. A method performed by the SSSA is also provided. An apparatus, system, and computer program product for performing similar methods are also provided.

Abstract: Techniques convert a first bitmap into a second bitmap. Such techniques involve determining a first plurality of bits in the first bitmap corresponding to a particular bit in the second bitmap; determining whether the first plurality of bits include a dirty bit as a unit of a processor line width; in response to determining that the first plurality of bits include a dirty bit, setting the particular bit as a dirty bit; and in response to determining that the first plurality of bits do not include a dirty bit, setting the particular bit as a non-dirty bit.

Abstract: The present invention relates to a mannanase PMan5A mutant having improved heat resistance, a gene encoding the mutant and application thereof. The mutant is obtained by a substitution of histidine with tyrosine at amino acid residue 93, phenylalanine with tyrosine at amino acid residue 94, leucine with histidine at amino acid residue 356, and/or alanine with proline at amino acid residue 389. The thermal tolerance of the single site mutation mutant H93Y, L356H and A389P are greatly improved over that of the wild-type mannanase PMan5A, and the thermal tolerance of the combination mutants shows the stack effect of the single site mutation, demonstrating the amino acids at the sites of 93, 94, 356, and 389 play an important role for the thermal stability of the mannanase of GH5 family.

Abstract: The present invention relates to mannanase PMan5A mutant having improved heat resistance, gene and application thereof. Said mutant is obtained by substitution the 93th histidine with tyrosine, the 94th phenylalanine with tyrosine, the 356th leucine with histidine, and/or the 389th alanine with proline.

Abstract: Techniques convert a first bitmap into a second bitmap. Such techniques involve determining a first plurality of bits in the first bitmap corresponding to a particular bit in the second bitmap; determining whether the first plurality of bits include a dirty bit as a unit of a processor line width; in response to determining that the first plurality of bits include a dirty bit, setting the particular bit as a dirty bit; and in response to determining that the first plurality of bits do not include a dirty bit, setting the particular bit as a non-dirty bit.

Abstract: Techniques for data synchronization involve obtaining a first bitmap about a first storage device, the first storage device including a group of storage areas, a bit in the first bitmap indicating whether data in a corresponding storage area of a first size in the group of storage areas is to be synchronized to a second storage device. The technique further involves, in response to a configuration of the first storage device being changed, determining a second size of a storage area in the group of storage areas. The technique further involves converting the first bitmap into a second bitmap based on the first size and the second size. In addition, the technique further involves synchronizing data from the first storage device to the second storage device based on the second size and the second bitmap.

Abstract: A method, device and system for synchronization message transmission are provided. The method may include that: a transmitting end selects at least one Ethernet Physical Layer Link (PHY) for synchronization message transmission from a Flexible Ethernet (FlexE) group (S201); after encapsulating the synchronization message according to a preset encapsulation strategy, the transmitting end inserts the synchronization message into a synchronization message channel in overhead of the selected Ethernet PHY (S202); and the transmitting end transmits the synchronization message through the selected Ethernet PHY (S203).

Abstract: Techniques for data synchronization involve obtaining a first bitmap about a first storage device, the first storage device including a group of storage areas, a bit in the first bitmap indicating whether data in a corresponding storage area of a first size in the group of storage areas is to be synchronized to a second storage device. The technique further involves, in response to a configuration of the first storage device being changed, determining a second size of a storage area in the group of storage areas. The technique further involves converting the first bitmap into a second bitmap based on the first size and the second size. In addition, the technique further involves synchronizing data from the first storage device to the second storage device based on the second size and the second bitmap.

Abstract: Techniques for data replication involve: in response to a first source state machine associated with a source file system being booted up, booting up a second source state machine associated with the source file system, the first source state machine performing a first operation for resizing a first storage area of data for replication from the source file system; transmitting a resizing message from the second source state machine to a destination file system, to enable the destination file system to perform a second operation for resizing a second storage area for storing the data to be replicated into the destination file system; and in response to the first operation and the second operation being successfully performed, enabling the data for replication from the source file system to be replicated into the destination file system.

Abstract: A method comprising: carrying out optimization of an item of software in a first intermediate representation; carrying out protection of the item of software in a second intermediate representation different to the first intermediate representation.

Abstract: A method, device and system for synchronization message transmission are provided. The method may include that: a transmitting end selects at least one Ethernet Physical Layer Link (PHY) for synchronization message transmission from a Flexible Ethernet (FlexE) group (S201); after encapsulating the synchronization message according to a preset encapsulation strategy, the transmitting end inserts the synchronization message into a synchronization message channel in overhead of the selected Ethernet PHY (S202); and the transmitting end transmits the synchronization message through the selected Ethernet PHY (S203).

Abstract: A chemical process to formulate conductive ink with low sintering temperature for inkjet printing is described and shown. The application of fabricated flexible conductive film on lithium ion batteries is also described. This chemical method and composition can remove the oxidation on metallic nanoparticle surface during ink fabrication and sintering processes. Etched metallic ions in the conductive ink are reduced and particles bridged while annealing printed patterns to achieve low temperature sintering at about 350° C. The chemical process can be applied on nickel materials that are excellent current collectors for lithium ion batteries due to high chemical stability especially at high charging-discharging potential of less than 3 Volts. Thermal decomposition and chemical reduction of silver salts are two methods disclosed for particle-free silver ink. Surfactant additive further make silver film more uniform and easier to be sintered.

Abstract: A chemical process to formulate conductive ink with low sintering temperature for inkjet printing is described and shown. The application of fabricated flexible conductive film on lithium ion batteries is also described. This chemical method and composition can remove the oxidation on metallic nanoparticle surface during ink fabrication and sintering processes. Etched metallic ions in the conductive ink are reduced and particles bridged while annealing printed patterns to achieve low temperature sintering at about 350° C. The chemical process can be applied on nickel materials that are excellent current collectors for lithium ion batteries due to high chemical stability especially at high charging-discharging potential of less than 3 Volts. Thermal decomposition and chemical reduction of silver salts are two methods disclosed for particle-free silver ink. Surfactant additive further make silver film more uniform and easier to be sintered.

Abstract: A method comprising: carrying out optimization of an item of software in a first intermediate representation; carrying out protection of the item of software in a second intermediate representation different to the first intermediate representation.