Abstract: A system for automatically generating responses to user queries includes one or more processors, operable when executing instructions to: receive a query from a user, determine a first set of similarity scores between the query and a plurality of stored queries stored in a data store, and determine whether a first similarity score of the first set of similarity scores meets a first threshold. In accordance with a determination that the first similarity score meets the first threshold, the processors are further operable to obtain a set of case information for the current case; retrieve case information for at least one precedent case; determine a second set of similarity scores between the current case and the at least one precedent case; determine whether a second similarity score of the second set of similarity scores meets a second threshold; and generate a response to the query.

Abstract: An exemplary system for constructing data structures that can perform inferential reasoning to answer input queries may receive input data, extract and cluster entities in the input data into topic clusters, and for a first topic cluster construct a data structure comprising a plurality of nodes, wherein nodes of the data structure respectively represent a topic entity extracted from the input data and grouped into the first topic cluster, and wherein a first node of the data structure is associated with a second node of the data structure based on the first node and the second node respectively representing a first topic entity and a second topic entity associated in the input data with a common one of the one or more identified linguistic modalities. An exemplary system comprising the data structure may receive an input query and generate a response to the input query using the data structure.

Abstract: Systems and methods for automated document processing for use in AI-augmented auditing platforms are provided. A system for determining the composition of document bundles extracts substantive content information and metadata information from a document bundle and generates, based on the extracted information regarding a composition of the document bundle. A system for validating signatures in documents extracts data representing a spatial location for respective signatures and generates a confidence level for respective signatures, and determines, based on location and confidence level, whether signature criteria are met. A system for extracting information from documents applies a set of data conversion processing steps to a plurality received documents to generate structured data, and then applies a set of knowledge-based modeling processing steps to the structured data to generating output data extracted from the plurality of electronic documents.

Abstract: A method for providing a hybrid AI and human electronic communication interface includes receiving a first electronic transmission comprising a user query from a user device. The method further includes automatically generating, by processing the user query by a set of AI models, an automatic response to the user query. The method further includes electronically transmitting the automatic response to the user device. The method further includes receiving, from the user device, a second electronic transmission comprising a user input in response to the automatic response. The method further includes determining, based at least in part on processing the user input, that a set of criteria is met; and in accordance with the determination that the set of criteria are met, automatically instantiating an electronic communication connection between the user device and a second user device.

Abstract: A system for automatically generating responses to user queries includes one or more processors, operable when executing instructions to: receive a query from a user, determine a first set of similarity scores between the query and a plurality of stored queries stored in a data store, and determine whether a first similarity score of the first set of similarity scores meets a first threshold. In accordance with a determination that the first similarity score meets the first threshold, the processors are further operable to obtain a set of case information for the current case; retrieve case information for at least one precedent case; determine a second set of similarity scores between the current case and the at least one precedent case; determine whether a second similarity score of the second set of similarity scores meets a second threshold; and generate a response to the query.

Abstract: Provided is a method for generating a personalized content suggestion in response to a query from a user. The method may be performed by a system comprising one or more processors. The method may include receiving the query from the user, generating one or more user parameters associated with the user, determining a predicted content topic of the query, and generating the content suggestion based on the predicted content topic and the one or more user parameters.

Abstract: Provided is a method for generating a knowledge graph for a topic. First, a set of documents may be received. A user may then provide an indication of exemplary entities associated with a topic of interest. Then, using one or more artificial intelligence models, a plurality of textual entities may be extracted from the documents. A quality level of each extracted textual entity may be determined. Each quality level may indicate a degree of similarity between a textual entity and each exemplary entity of the one or more exemplary entities. Next, a plurality of high-quality textual entities may be identified and categorized according to one or more sub-topics associated with the topic. Connection information indicating relationships between the sub-topics may be determined. Finally, a knowledge graph for the topic that represents the sub-topics in the documents and the relationships between said sub-topics may be generated.

Abstract: An exemplary system for constructing data structures that can perform inferential reasoning to answer input queries may receive input data, extract and cluster entities in the input data into topic clusters, and for a first topic cluster construct a data structure comprising a plurality of nodes, wherein nodes of the data structure respectively represent a topic entity extracted from the input data and grouped into the first topic cluster, and wherein a first node of the data structure is associated with a second node of the data structure based on the first node and the second node respectively representing a first topic entity and a second topic entity associated in the input data with a common one of the one or more identified linguistic modalities. An exemplary system comprising the data structure may receive an input query and generate a response to the input query using the data structure.

Abstract: A line driver includes a first resistive component, a second resistive component, an operational amplifier and an adjustable current mirror array circuit. A first terminal of the second resistive component and the first resistive component are coupled to a node, and a second terminal of the second resistive component is coupled to an output terminal. The operational amplifier receives a common mode voltage through the first resistive component, and generates a first signal and a second signal according to the common mode voltage and an input signal. The adjustable current mirror array circuit generates a first current to the node and a second current to the output terminal in response to the first and second signals, and adjusts a ratio of the second current to the first current in response to multiple control bits so as to set an output impedance of the output terminal.

Abstract: An audio player device includes a digital-to-analog converter (DAC), a startup circuit, a multiplexer and an output amplifier. The DAC converts audio data into a first signal and a second signal. The startup circuit gradually increases a level of a startup voltage according to a reference voltage during a predetermined period. The multiplexer outputs the startup voltage as a control voltage during the predetermined period, and switches to output the reference voltage as the control voltage after the predetermined period has elapsed. The output amplifier generates an audio signal according to the control voltage, the first signal and the second signal. The control voltage is used to set a common mode voltage of the output amplifier.

Abstract: A wired transceiver includes an output stage circuit and an input stage circuit. The output stage operates in one of a first mode and a second mode according to a mode control signal, and transmits multiple output signals to multiple output pads and receives a first set of bias voltages to provide a first overvoltage protection in the first mode, and stops transmitting the output signals and receives a second set of bias voltages to provide the overvoltage protection in the second mode. The input stage circuit receives multiple input signals from the output pads when the output stage circuit operates in the second mode, and attenuates the input signal to provide a second overvoltage protection.

Abstract: A line driver includes a first resistive component, a second resistive component, an operational amplifier and an adjustable current mirror array circuit. A first terminal of the second resistive component and the first resistive component are coupled to a node, and a second terminal of the second resistive component is coupled to an output terminal. The operational amplifier receives a common mode voltage through the first resistive component, and generates a first signal and a second signal according to the common mode voltage and an input signal. The adjustable current mirror array circuit generates a first current to the node and a second current to the output terminal in response to the first and second signals, and adjusts a ratio of the second current to the first current in response to multiple control bits so as to set an output impedance of the output terminal.

Abstract: Systems and methods for automated document processing for use in AI-augmented auditing platforms are provided. A system for determining the composition of document bundles extracts substantive content information and metadata information from a document bundle and generates, based on the extracted information regarding a composition of the document bundle. A system for validating signatures in documents extracts data representing a spatial location for respective signatures and generates a confidence level for respective signatures, and determines, based on location and confidence level, whether signature criteria are met. A system for extracting information from documents applies a set of data conversion processing steps to a plurality received documents to generate structured data, and then applies a set of knowledge-based modeling processing steps to the structured data to generating output data extracted from the plurality of electronic documents.

Abstract: Lipid-based probes and systems therewith to capture and isolate extracellular vesicles from a sample are disclosed. The system can include a labelling probe-capture probe combination or an immobilized labelling probe on a surface of a substrate or a device including the immobilized labelling probe on a surface of a substrate. The labelling probe can include a lipid tail for insertion in the lipid bilayer membrane of extracellular vesicles. The labelling probe can further include a tag that can be readily combine with a capture probe or a high affinity component to bind to a substrate surface to immobilize the labelling probe, and a spacer between the lipid tail and tag or high affinity component.

Abstract: In one aspect, methods of detecting tumor cells are described herein. In some embodiments, a method of detecting tumor cells comprises providing a device, the device comprising a substrate surface and a plurality of first aptamer probes attached to the substrate surface. The method further comprises contacting a plurality of cells with the plurality of first aptamer probes attached to the substrate surface; adhering one or more of the plurality of cells to the substrate surface; and measuring a non-uniformity parameter, a Hausdorff distance, a change in the number of pseudopods, and/or a shape of at least one adhered cell. In some cases, the method further comprises using the non-uniformity parameter, Hausdorff distance, change in the number of pseudopods, and/or shape of the adhered cell to identify the adhered cell as a tumor cell or a non-tumor cell.

Abstract: In one aspect, methods of detecting tumor cells are described herein. In some embodiments, a method of detecting tumor cells comprises providing a device, the device comprising a substrate surface and a plurality of first aptamer probes attached to the substrate surface. The method further comprises contacting a plurality of cells with the plurality of first aptamer probes attached to the substrate surface; adhering one or more of the plurality of cells to the substrate surface; and measuring a non-uniformity parameter, a Hausdorff distance, a change in the number of pseudopods, and/or a shape of at least one adhered cell. In some cases, the method further comprises using the non-uniformity parameter, Hausdorff distance, change in the number of pseudopods, and/or shape of the adhered cell to identify the adhered cell as a tumor cell or a non-tumor cell.

Abstract: In one aspect, methods of detecting tumor cells are described herein. In some embodiments, a method of detecting tumor cells comprises providing a device, the device comprising a substrate surface and a plurality of first aptamer probes attached to the substrate surface. The method further comprises contacting a plurality of cells with the plurality of first aptamer probes attached to the substrate surface; adhering one or more of the plurality of cells to the substrate surface; and measuring a non-uniformity parameter, a Hausdorff distance, a change in the number of pseudopods, and/or a shape of at least one adhered cell. In some cases, the method further comprises using the non-uniformity parameter, Hausdorff distance, change in the number of pseudopods, and/or shape of the adhered cell to identify the adhered cell as a tumor cell or a non-tumor cell.

Abstract: Devices, systems, and methods for detecting protein-nucleic acid and cell-nucleic acid hybridization, using surface-tethered aptamer probes, without the use of labeling or target modification and capable of recycling.

Abstract: In one aspect, methods of detecting tumor cells are described herein. In some embodiments, a method of detecting tumor cells comprises providing a device, the device comprising a substrate surface and a plurality of first aptamer probes attached to the substrate surface. The method further comprises contacting a plurality of cells with the plurality of first aptamer probes attached to the substrate surface; adhering one or more of the plurality of cells to the substrate surface; and measuring a non-uniformity parameter, a Hausdorff distance, a change in the number of pseudopods, and/or a shape of at least one adhered cell. In some cases, the method further comprises using the non-uniformity parameter, Hausdorff distance, change in the number of pseudopods, and/or shape of the adhered cell to identify the adhered cell as a tumor cell or a non-tumor cell.

Abstract: The present invention provides a hybrid coupling structure of a short range surface plasmon polariton and a conventional dielectric waveguide, including a dielectric substrate layer, a dielectric waveguide layer positioned on the said dielectric substrate layer, a coupling matching layer positioned on the said dielectric waveguide layer and a short range surface plasmon waveguide portion, formed on the said coupling matching layer, for conducting the short range surface plasmon polariton. The present invention also provides a coupling structure of a long range surface plasmon polariton and a dielectric waveguide, including a dielectric substrate layer, a dielectric waveguide layer, a coupling matching layer and a long range surface plasmon waveguide portion upward from below respectively.