Abstract: Embodiments of a three-dimensional (3D) memory device and a method of operating the 3D memory device are provided. The 3D memory device includes an array of 3D NAND memory cells, an array of static random-access memory (SRAM) cells, and a peripheral circuit. The array of SRAM cells and the peripheral circuit arranged at one side are bonded with the array of 3D NAND memory cells at another side to form a chip. Data is received from a host through the peripheral circuit, buffered in the array of SRAM cells, and transmitted from the array of SRAM cells to the array of 3D NAND memory cells. The data is programmed into the array of 3D NAND memory cells.

Abstract: A line driver includes a first resistive component, a second resistive component, an operational amplifier and an adjustable current mirror array circuit. A first terminal of the second resistive component and the first resistive component are coupled to a node, and a second terminal of the second resistive component is coupled to an output terminal. The operational amplifier receives a common mode voltage through the first resistive component, and generates a first signal and a second signal according to the common mode voltage and an input signal. The adjustable current mirror array circuit generates a first current to the node and a second current to the output terminal in response to the first and second signals, and adjusts a ratio of the second current to the first current in response to multiple control bits so as to set an output impedance of the output terminal.

Abstract: An audio player device includes a digital-to-analog converter (DAC), a startup circuit, a multiplexer and an output amplifier. The DAC converts audio data into a first signal and a second signal. The startup circuit gradually increases a level of a startup voltage according to a reference voltage during a predetermined period. The multiplexer outputs the startup voltage as a control voltage during the predetermined period, and switches to output the reference voltage as the control voltage after the predetermined period has elapsed. The output amplifier generates an audio signal according to the control voltage, the first signal and the second signal. The control voltage is used to set a common mode voltage of the output amplifier.

Abstract: A wired transceiver includes an output stage circuit and an input stage circuit. The output stage operates in one of a first mode and a second mode according to a mode control signal, and transmits multiple output signals to multiple output pads and receives a first set of bias voltages to provide a first overvoltage protection in the first mode, and stops transmitting the output signals and receives a second set of bias voltages to provide the overvoltage protection in the second mode. The input stage circuit receives multiple input signals from the output pads when the output stage circuit operates in the second mode, and attenuates the input signal to provide a second overvoltage protection.

Abstract: A line driver includes a first resistive component, a second resistive component, an operational amplifier and an adjustable current mirror array circuit. A first terminal of the second resistive component and the first resistive component are coupled to a node, and a second terminal of the second resistive component is coupled to an output terminal. The operational amplifier receives a common mode voltage through the first resistive component, and generates a first signal and a second signal according to the common mode voltage and an input signal. The adjustable current mirror array circuit generates a first current to the node and a second current to the output terminal in response to the first and second signals, and adjusts a ratio of the second current to the first current in response to multiple control bits so as to set an output impedance of the output terminal.

Abstract: Systems and methods for automated document processing for use in AI-augmented auditing platforms are provided. A system for determining the composition of document bundles extracts substantive content information and metadata information from a document bundle and generates, based on the extracted information regarding a composition of the document bundle. A system for validating signatures in documents extracts data representing a spatial location for respective signatures and generates a confidence level for respective signatures, and determines, based on location and confidence level, whether signature criteria are met. A system for extracting information from documents applies a set of data conversion processing steps to a plurality received documents to generate structured data, and then applies a set of knowledge-based modeling processing steps to the structured data to generating output data extracted from the plurality of electronic documents.

Abstract: Lipid-based probes and systems therewith to capture and isolate extracellular vesicles from a sample are disclosed. The system can include a labelling probe-capture probe combination or an immobilized labelling probe on a surface of a substrate or a device including the immobilized labelling probe on a surface of a substrate. The labelling probe can include a lipid tail for insertion in the lipid bilayer membrane of extracellular vesicles. The labelling probe can further include a tag that can be readily combine with a capture probe or a high affinity component to bind to a substrate surface to immobilize the labelling probe, and a spacer between the lipid tail and tag or high affinity component.

Abstract: In one aspect, methods of detecting tumor cells are described herein. In some embodiments, a method of detecting tumor cells comprises providing a device, the device comprising a substrate surface and a plurality of first aptamer probes attached to the substrate surface. The method further comprises contacting a plurality of cells with the plurality of first aptamer probes attached to the substrate surface; adhering one or more of the plurality of cells to the substrate surface; and measuring a non-uniformity parameter, a Hausdorff distance, a change in the number of pseudopods, and/or a shape of at least one adhered cell. In some cases, the method further comprises using the non-uniformity parameter, Hausdorff distance, change in the number of pseudopods, and/or shape of the adhered cell to identify the adhered cell as a tumor cell or a non-tumor cell.

Abstract: In one aspect, methods of detecting tumor cells are described herein. In some embodiments, a method of detecting tumor cells comprises providing a device, the device comprising a substrate surface and a plurality of first aptamer probes attached to the substrate surface. The method further comprises contacting a plurality of cells with the plurality of first aptamer probes attached to the substrate surface; adhering one or more of the plurality of cells to the substrate surface; and measuring a non-uniformity parameter, a Hausdorff distance, a change in the number of pseudopods, and/or a shape of at least one adhered cell. In some cases, the method further comprises using the non-uniformity parameter, Hausdorff distance, change in the number of pseudopods, and/or shape of the adhered cell to identify the adhered cell as a tumor cell or a non-tumor cell.

Abstract: In one aspect, methods of detecting tumor cells are described herein. In some embodiments, a method of detecting tumor cells comprises providing a device, the device comprising a substrate surface and a plurality of first aptamer probes attached to the substrate surface. The method further comprises contacting a plurality of cells with the plurality of first aptamer probes attached to the substrate surface; adhering one or more of the plurality of cells to the substrate surface; and measuring a non-uniformity parameter, a Hausdorff distance, a change in the number of pseudopods, and/or a shape of at least one adhered cell. In some cases, the method further comprises using the non-uniformity parameter, Hausdorff distance, change in the number of pseudopods, and/or shape of the adhered cell to identify the adhered cell as a tumor cell or a non-tumor cell.

Abstract: Devices, systems, and methods for detecting protein-nucleic acid and cell-nucleic acid hybridization, using surface-tethered aptamer probes, without the use of labeling or target modification and capable of recycling.

Abstract: In one aspect, methods of detecting tumor cells are described herein. In some embodiments, a method of detecting tumor cells comprises providing a device, the device comprising a substrate surface and a plurality of first aptamer probes attached to the substrate surface. The method further comprises contacting a plurality of cells with the plurality of first aptamer probes attached to the substrate surface; adhering one or more of the plurality of cells to the substrate surface; and measuring a non-uniformity parameter, a Hausdorff distance, a change in the number of pseudopods, and/or a shape of at least one adhered cell. In some cases, the method further comprises using the non-uniformity parameter, Hausdorff distance, change in the number of pseudopods, and/or shape of the adhered cell to identify the adhered cell as a tumor cell or a non-tumor cell.

Abstract: The present invention provides a hybrid coupling structure of a short range surface plasmon polariton and a conventional dielectric waveguide, including a dielectric substrate layer, a dielectric waveguide layer positioned on the said dielectric substrate layer, a coupling matching layer positioned on the said dielectric waveguide layer and a short range surface plasmon waveguide portion, formed on the said coupling matching layer, for conducting the short range surface plasmon polariton. The present invention also provides a coupling structure of a long range surface plasmon polariton and a dielectric waveguide, including a dielectric substrate layer, a dielectric waveguide layer, a coupling matching layer and a long range surface plasmon waveguide portion upward from below respectively.

Abstract: Devices, systems, and methods for detecting protein-nucleic acid and cell-nucleic acid hybridization, using surface-tethered aptamer probes, without the use of labeling or target modification and capable of recycling.

Abstract: The present invention provides a hybrid coupling structure of a short range surface plasmon polariton and a conventional dielectric waveguide, including a dielectric substrate layer, a dielectric waveguide layer positioned on the said dielectric substrate layer, a coupling matching layer positioned on the said dielectric waveguide layer and a short range surface plasmon waveguide portion, formed on the said coupling matching layer, for conducting the short range surface plasmon polariton. The present invention also provides a coupling structure of a long range surface plasmon polariton and a dielectric waveguide, including a dielectric substrate layer, a dielectric waveguide layer, a coupling matching layer and a long range surface plasmon waveguide portion upward from below respectively.

Abstract: A handwriting recognition system with a wireless pen and a tablet. The wireless pen has an eraser button which is used to let an eraser mode be performed while the eraser button being process, the tablet receive messages from wireless pen and decide the location of wireless pen and current mode of handwriting recognition system. The method of using the handwriting recognition system at least has follows. Move the wireless pen over the tablet so let these messages be received by the tablet, and switch the current mode of the handwriting recognition system between an eraser mode and a writing mode. however, the terminal with coil of the wireless pen always is more closed to the tablet than the other terminal.