Abstract: A multi-layer federated learning method based on distributed clustering is provided, which comprises the following steps. Computing a feature distribution similarity for each of participating nodes with non-(non-independent and identically distributed) data sets, and grouping these nodes into plural clusters by the feature distribution similarity. Updating local model of nodes of each cluster by a federated learning algorithm, and inputting these nodes into a multi-layer aggregation mechanism. Terminating the operation of the multi-layer aggregation mechanism until the clustering result meets a required demand. Furthermore, we implement a blockchain-based multi-layer federated learning system, including model aggregation module, API module, time-series synchronization module, and IPFS, based on distributed clustering architecture. The learning performance is proven to effectively improved.

Abstract: A medical data ownership management method comprises: Granting a first authority to a medical unit where the first authority allows the medical unit to generate a first medical object with its corresponding first non-fungible token (NFT) storing on a blockchain. Granting a second authority to a research unit, where the second authority allows the research unit to access the first medical object, and the research unit processes the first medical object to generate the second medical object with its corresponding second NFT storing on the blockchain. Finally, granting a third authority to a user unit, where the third authority allows the user unit to access the second medical object. The access control and ownership transfer of each medial object in the blockchain are achieved by trading the corresponding NFT and modifying its subordinate list. With the management method, the security and the privacy of the medical data will be enhanced.

Abstract: A light source apparatus for fluorescence photography of biomolecule sample gels is disclosed. The light source apparatus comprises a housing, a transparent plate disposed in a light transmission zone at the top of the housing, and at least one LED array disposed in the housing out of the range of the light transmission zone. The LED array irradiates obliquely to the light transmission zone for preventing the light spots from interfering in the observation. Each of LED array may comprises different colors of LEDs for different biomolecule samples.

Abstract: A real-time fluorescent electrophoresis apparatus, comprising: an electrophoresis tank comprising a platform, an electrophoresis liquid, a positive electrode and a negative electrode, the platform carrying a gel with a biological sample, the gel comprising a plurality of charged molecules of the biological sample, and the gel, the platform, the positive electrode and the negative electrode being immersed in the electrophoresis liquid; and a lid covering the electrophoresis tank and comprising a filter disposed above the gel and at least one luminous element disposed on at least one side of the filter to irradiate the gel so that the biological sample in the gel is excited to fluoresce. Thereby, the experimenter is able to observe fluorescence phenomenon from the biological sample during electrophoresis so as to trace the electrophoresis process and determine whether the electrophoresis process is to be interrupted and avoid experimental errors.

Abstract: The present invention relates to a cooling device, mainly comprises a carrying unit, a thermal insulation unit, and a temperature-lowering module. The thermal insulation unit is provided over a part of surface of the carrying unit for blocking heat transmission between the carrying unit and the outside. As the carrying unit is placed on the temperature-lowering module, a cooling chip in the temperature-lowering module is able to lower the temperature of the carrying unit and a biological sample. Furthermore, the thermal insulation unit is able to maintain the temperature of the carrying unit and biological sample, when the carrying unit is removed from the temperature-lowering module. Thereafter, a user can conveniently practice observation and experiment with respect to the biological sample, and avoid damaging the biological sample during experiment or transportation by the use of the cooling device.

Abstract: A high-performance light source apparatus for fluorescence photography of biomolecule sample gels is disclosed. The high-performance light source apparatus comprises a base frame, a supporting region located on the center of the top surface of the base frame for supporting a biomolecule sample gel, and at least one light-emitting module disposed on the top surface of the base frame around the supporting region for emitting an exciting light onto the biomolecule sample gel laterally. Each light-emitting module comprises an LED array having different colors of LEDs for different bio reagents. The exciting light is projected onto the biomolecule sample gel laterally, such that the size of the high-performance light source apparatus can be minimized, and the light spots interference in fluorescence photographing or observation can be prevented.

Abstract: A light source apparatus for fluorescence photography of biomolecule sample gels is disclosed. The light source apparatus comprises a housing, a transparent plate disposed in a light transmission zone at the top of the housing, and at least one LED array disposed in the housing out of the range of the light transmission zone. The LED array irradiates obliquely to the light transmission zone for preventing the light spots from interfering in the observation. Each of LED array may comprises different colors of LEDs for different biomolecule samples.