Patents by Inventor Yuan Yuan Zhang

Yuan Yuan Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vitro engineered, regenerated urinary tract tissue compositions and methods for producing same
    Publication number: 20090304645
    Abstract: A method for providing a urinary tract tissue graft composition includes providing a tissue culture frame and a segment of small intestinal submucosa and positioning the segment of small intestinal submucosa in the tissue culture frame such that the segment of small intestinal submucosa is suspended and held in a taut position by the tissue culture frame. Smooth muscle and urothelial cells are isolated from a tissue specimen of a subject and cultured, and then seeded upon the segment of small intestinal submucosa, thereby forming a urinary tract tissue graft. A tissue culture frame in which such a urinary tract tissue graft may be formed is also disclosed.
    Type: Application
    Filed: June 16, 2009
    Publication date: December 10, 2009
    Inventors: Bradley P. Kropp, Earl Y. Cheng, Yuan Yuan Zhang, Rick Cowan, Peter Moore
  • Urinary tract tissue graft compositions and methods for producing same
    Patent number: 7507422
    Abstract: A method for repairing damaged or diseased urinary tract tissue includes providing a urinary tract tissue graft composition that includes a distal ileal segment of small intestinal submucosa. The distal ileal segment of small intestinal submucosa may be utilized as an unseeded tissue graft composition, or the distal ileal segment of small intestinal submucosa may be positioned in a tissue culture frame, and smooth muscle and urothelial cells isolated from a tissue specimen of a subject and cultured are then seeded upon the distal ileal segment of small intestinal submucosa, thereby forming a urinary tract tissue graft.
    Type: Grant
    Filed: January 5, 2006
    Date of Patent: March 24, 2009
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Bradley P. Kropp, Yuan Yuan Zhang, Earl Y. Cheng, Hsueh-Kung Lin, Rick Cowan
  • Urinary tract tissue graft compositions and methods for producing same
    Patent number: 7344712
    Abstract: A method for providing a urinary tract tissue graft composition includes providing a segment of small intestinal submucosa and positioning the segment of small intestinal submucosa in a tissue culture frame such that the segment of small intestinal submucosa is suspended and held in a taut position by the tissue culture frame. At least one multipotent cell type is isolated from a tissue specimen of a subject and cultured, and then seeded upon a surface of the segment of small intestinal submucosa, thereby forming a urinary tract tissue graft. Methods for repairing a damaged urinary tract tissue of a subject are also disclosed.
    Type: Grant
    Filed: July 31, 2003
    Date of Patent: March 18, 2008
    Assignee: The Board of Regent of the University of Oklahoma
    Inventors: Bradley Kropp, Earl Y. Cheng, Yuan Yuan Zhang, Hsueh-Kung Lin, Rick Cowan
  • Vitro engineered, regenerated urinary tract tissue compositions and methods for producing same
    Patent number: 7122200
    Abstract: A method for providing a urinary tract tissue graft composition includes providing a tissue culture frame and a segment of small intestinal submucosa and positioning the segment of small intestinal submucosa in the tissue culture frame such that the segment of small intestinal submucosa is suspended and held in a taut position by the tissue culture frame. Smooth muscle and urothelial cells are isolated from a tissue specimen of a subject and cultured, and then seeded upon the segment of small intestinal submucosa, thereby forming a urinary tract tissue graft. A tissue culture frame in which such a urinary tract tissue graft may be formed is also disclosed.
    Type: Grant
    Filed: December 10, 2001
    Date of Patent: October 17, 2006
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Bradley P. Kropp, Earl Y. Cheng, Yuan Yuan Zhang, Rick Cowan, Peter Moore
  • Urinary tract tissue graft compositions and methods for producing same
    Patent number: 7078033
    Abstract: A method for repairing damaged or diseased urinary tract tissue includes providing a urinary tract tissue graft composition that includes a distal ileal segment of small intestinal submucosa. The distal ileal segment of small intestinal submucosa may be utilized as an unseeded tissue graft composition, or the distal ileal segment of small intestinal submucosa may be positioned in a tissue culture frame, and smooth muscle and urothelial cells isolated from a tissue specimen of a subject and cultured are then seeded upon the distal ileal segment of small intestinal submucosa, thereby forming a urinary tract tissue graft.
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: July 18, 2006
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Bradley P. Kropp, Yuan Yuan Zhang, Earl Y. Cheng, Hsueh-Kung Lin, Rick Cowan
  • Urinary tract tissue graft compositions and methods for producing same
    Publication number: 20040091461
    Abstract: A method for providing a urinary tract tissue graft composition includes providing a segment of small intestinal submucosa and positioning the segment of small intestinal submucosa in a tissue culture frame such that the segment of small intestinal submucosa is suspended and held in a taut position by the tissue culture frame. At least one multipotent cell type is isolated from a tissue specimen of a subject and cultured, and then seeded upon a surface of the segment of small intestinal submucosa, thereby forming a urinary tract tissue graft. Methods for repairing a damaged urinary tract tissue of a subject are also disclosed.
    Type: Application
    Filed: July 31, 2003
    Publication date: May 13, 2004
    Inventors: Bradley Kropp, Earl Y. Cheng, Yuan Yuan Zhang, H.K. Lin, Rick Cowan
  • Urinary tract tissue graft compositions and methods for producing same
    Publication number: 20030165474
    Abstract: A method for repairing damaged or diseased urinary tract tissue includes providing a urinary tract tissue graft composition that includes a distal ileal segment of small intestinal submucosa. The distal ileal segment of small intestinal submucosa may be utilized as an unseeded tissue graft composition, or the distal ileal segment of small intestinal submucosa may be positioned in a tissue culture frame, and smooth muscle and urothelial cells isolated from a tissue specimen of a subject and cultured are then seeded upon the distal ileal segment of small intestinal submucosa, thereby forming a urinary tract tissue graft.
    Type: Application
    Filed: December 6, 2002
    Publication date: September 4, 2003
    Inventors: Bradley P. Kropp, Yuan Yuan Zhang, Earl Y. Cheng, H.K. Lin, Rick Cowan
  • In vitro engineered, regenerated urinary tract tissue compositions and methods for producing same
    Publication number: 20020087214
    Abstract: A method for providing a urinary tract tissue graft composition includes providing a tissue culture frame and a segment of small intestinal submucosa and positioning the segment of small intestinal submucosa in the tissue culture frame such that the segment of small intestinal submucosa is suspended and held in a taut position by the tissue culture frame. Smooth muscle and urothelial cells are isolated from a tissue specimen of a subject and cultured, and then seeded upon the segment of small intestinal submucosa, thereby forming a urinary tract tissue graft. A tissue culture frame in which such a urinary tract tissue graft may be formed is also disclosed.
    Type: Application
    Filed: December 10, 2001
    Publication date: July 4, 2002
    Inventors: Bradley P. Kropp, Earl Y. Cheng, Yuan Yuan Zhang, Rick Cowan, Peter Moore