Abstract: The present invention provides intraocular polymer delivery compositions based on biodegradable polyester amide (PEA), polyester urethane (PEUR), and polyester urea (PEU) polymers, which contain amino acids. The compositions can be formulated as an implantable solid or as a liquid dispersion of polymer particles for sustained delivery of ophthalmologic agents dispersed therein or incorporated into the backbone of the polymers. Methods of delivering an ophthalmologic agent to the exterior or interior of the eye by implanting the composition in the eye of a subject are also included.