Abstract: Compositions and methods provide a health benefit to a growing animal by administering a food composition to the animal, and the food composition includes a brain development blend. The brain development blend generally contains DHA, EPA, taurine, choline, thiamine, riboflavin, pantothenic acid, niacin, pyridoxine, vitamin B12, and folic acid.

Abstract: A method of mimicking health benefits of physical exercise in a cat can include administering a high protein diet to a cat, the high protein diet including from about 110% to about 350% of a Recommended Daily Allowance (RDA) of protein for the cat on a daily basis. The high protein diet in this example is sufficient to increase a 12,13-diHOME blood level for an 18-24 hour period per day compared to a baseline blood level without the need for physical exercise.

Abstract: A method of mimicking health benefits of physical exercise or voluntary cold exposure, e.g., cold plunge, in an animal can include administering to the animal a high protein diet including from about 150% to about 400% of a Recommended Daily Allowance (RDA) of protein for the animal on a daily basis. The high protein diet can be sufficient to increase a 12,13-diHOME blood level for an 18-24 hour period per day compared to a baseline blood level without the need for the physical exercise or voluntary cold exposure.

Abstract: Compositions and methods can use at least one of (a) a combination of spermidine and ellagic acid or (b) a combination of docosahexaenoic acid (DHA) and curcumin to enhance cognition and emotional health in a mammal. The mammal is preferably an ageing or elderly human or an ageing or elderly companion animal, preferably an elderly dog.

Abstract: The present disclosure provides methods and compositions for treating glomerular hyperfiltration, reducing glycogen storage in tissues, or reducing uremic toxins in an animal, comprising orally administering a composition comprising medium chain triglycerides, eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), arginine, antioxidants, and B vitamins to the animal.

Abstract: Compositions include arginine and one or more unsaturated fatty acids. Methods for using such compositions can enhance cognitive function, reduce or prevent a decline of social interaction, reduce or prevent age-related behavioral changes, increase trainability, maintain optimal brain function, facilitate learning and memory, reduce memory loss, retard brain aging, prevent or treat strokes, and/or prevent or treat dementia in an animal. Preferably, the compositions are food compositions useful for enhancing cognitive function in humans and companion animals.

Abstract: The present disclosure provides a method of determining the efficacy of a weight loss diet for a canine, the method comprising analyzing a serum or plasma sample from the canine for a biomarker before and after administration of the weight loss diet, wherein the biomarker is selected from the group consisting of 3-methylhistidine, 1-methylhistidine, and a combination thereof, and determining the weight loss diet is efficacious if the amount of the biomarker has decreased.

Abstract: Compositions and methods directed to a synergistic blend of amino acids for providing a health benefit to an animal are disclosed herein.

Abstract: The present disclosure provides compositions and methods for providing a health benefit in an animal comprising administering a food composition to the animal, where the food composition comprises protein, fat, carbohydrates, omega-3 fatty acids, and isoflavones; where the protein to carbohydrate is in a ratio ranging from 3.5:1 to 2.5:1 by weight as fed.

Abstract: The present disclosure provides compositions and methods for providing a health benefit in an animal comprising administering a food composition to the animal, wherein the food composition comprises: from about 25% to about 60% protein, from about 15% to about 45% fat, and from about 5% to about 25% carbohydrate, where the caloric contribution ratio of protein to carbohydrate ranges from 3.5:1 to 2.5:1, the caloric contribution ratio of fat to carbohydrate ranges from 2.5:1 to 1.5:1, and the caloric contribution ratio of protein to fat ranges from 3:1 to 1:1.

Abstract: Methods and compositions for providing a health benefit to an animal using a nutrient blend. In one embodiment, the method can comprise orally administering a composition comprising at least four of the nutrients selected from the group of walnut, maitake mushroom extract, EGCG, turmeric root powder, lycopene, taurine, EPA, and DHA to the animal.

Abstract: The invention provides compositions and methods for metabolic health in an animal comprising administering a non-ketogenic composition to the animal, wherein the non-ketogenic composition comprises about 5% to about 25% carbohydrates, about 30% to about 60% protein, and about 10% to about 40% fat. Additionally, the composition can have a protein to carbohydrate ratio of at least 2:1.

Abstract: Methods and compositions for providing a health benefit to an animal using a nutrient blend. In one embodiment, the method can comprise orally administering a composition comprising at least four of the nutrients selected from the group of walnut, maitake mushroom extract, EGCG, turmeric root powder, lycopene, taurine, EPA, and DHA to the animal.

Abstract: Methods and compositions for providing a health benefit to an animal using a nutrient blend. In one embodiment, the method can comprise orally administering a composition comprising at least four of the nutrients selected from the group of walnut, maitake mushroom extract, EGCG, turmeric root powder, lycopene, taurine, EPA, and DHA to the animal.

Abstract: The invention provides methods for treating, preventing, or delaying the onset of an organ disease in an animal and for reducing the biological age in an adult animal using an intermittent partially restricted diet. Such methods can include feeding an animal two different diets having differing caloric contents in a specific ratio to achieve such benefits.

Abstract: A method of enhancing vaccine efficacy, treating or preventing an allergy, or treating or preventing an autoimmune disease in an animal can comprise administering to the animal a composition comprising colostrum.

Abstract: Compositions include arginine and one or more unsaturated fatty acids. Methods for using such compositions can enhance cognitive function, reduce or prevent a decline of social interaction, reduce or prevent age-related behavioral changes, increase trainability, maintain optimal brain function, facilitate learning and memory, reduce memory loss, retard brain aging, prevent or treat strokes, and/or prevent or treat dementia in an animal. Preferably, the compositions are food compositions useful for enhancing cognitive function in humans and companion animals.

Abstract: The present disclosure provides compositions and methods for providing a health benefit to a growing animal comprising administering a food composition to the animal, wherein the food composition includes a brain development blend. The brain development blend generally comprises DHA, EPA, taurine, choline, thiamine, riboflavin, pantothenic acid, niacin, pyridoxine, vitamin B12, and folic acid.

Abstract: A method of minimizing fat accumulation in a growing animal without limiting caloric intake or preventing or treating obesity in an animal, the method comprising orally administering a ketogenic diet and a nutrient blend to the animal. The nutrient blend can include at least four nutrients selected from the group consisting of walnut, maitake mushroom extract, EGCG, turmeric root powder, lycopene, taurine, EPA, and DHA to the animal.

Abstract: Compositions include arginine and one or more unsaturated fatty acids. Methods for using such compositions can enhance cognitive function, reduce or prevent a decline of social interaction, reduce or prevent age-related behavioral changes, increase trainability, maintain optimal brain function, facilitate learning and memory, reduce memory loss, retard brain aging, prevent or treat strokes, and/or prevent or treat dementia in an animal. Preferably, the compositions are food compositions useful for enhancing cognitive function in humans and companion animals.