Abstract: The present disclosure provides an acrylamide production system. The acrylamide production system includes a storage device, a reaction kettle, a filter device, an impurity removal device, and a collection device. The storage device is used for storing microbes required for a reaction. A discharge end of the storage device is connected to a feed end of the reaction kettle through a pipeline. A discharge end of the reaction kettle is connected to a feed end of the filter device through a pipeline. A filtrate discharge end of the filter device is connected to a feed end of the impurity removal device through a pipeline. A discharge end of the impurity removal device is connected to the collection device through a pipeline. According to the acrylamide production system of the present disclosure, the whole process for producing an acrylamide aqueous solution is simple, which facilitates producing a high-purity acrylamide solution.