Patents by Inventor Yuanqing Yan

Yuanqing Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SPINK1 AS A TARGET FOR THERAPEUTIC INTERVENTION IN LUNG DISEASES
    Publication number: 20240343828
    Abstract: Provided herein is a method of treating or preventing acute or chronic lung disease in a subject, comprising administering an agent that modulates the expression of Serine Protease Inhibitor Kazal-type 1 (SPINK1) to the subject.
    Type: Application
    Filed: March 4, 2024
    Publication date: October 17, 2024
    Applicant: Northwestern University
    Inventors: Ankit Bharat, Yuanqing Yan, GR Scott Budinger, Ali Shilatifard
  • DIAGNOSIS OF ACUTE AND CHRONIC LUNG DISEASES BY QUANTIFYING SPINK1 LEVEL
    Publication number: 20240309453
    Abstract: Provided herein is a method of detecting the presence or absence of Serine Protease Inhibitor Kazal-type 1 (SPINK1) in a subject, comprising obtaining a biological sample comprising genomic DNA from a subject having or suspected of having chronic and acute lung diseases, and detecting the presence or absence of the SPINK1 in the biological sample.
    Type: Application
    Filed: March 4, 2024
    Publication date: September 19, 2024
    Applicant: Northwestern University
    Inventors: Ankit Bharat, Yuanqing Yan
  • METHODS AND REAGENTS FOR CHARACTERIZING THSD1 FUNCTION
    Publication number: 20230212522
    Abstract: The disclosure describes global transcriptome profiling in human vascular endothelial cells upon THSD1 knockdown and identification from these studies of specific genes and pathways that are THSD1. The analysis highlights a role for THSD1 in regulating endothelial to mesenchymal transition and other pathways. The analysis also demonstrates that endothelial cell injury is the first event of an intracranial aneurysm. The disclosure provides novel cell lines and reagents used for better understanding the molecular mechanism of THSD1 biology.
    Type: Application
    Filed: May 25, 2022
    Publication date: July 6, 2023
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Dong H. Kim, Yuanqing Yan, Yanning Rui, Zhen Xu, John Hagan