Patents by Inventor Yuanqing Zhou

Yuanqing Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240085717
    Abstract: Disclosed are a super-resolution imaging system (1, 41, 51), a super-resolution imaging method, a biological sample identification system (4, 61) and method, a nucleic acid sequencing imaging system (5) and method, and a nucleic acid identification system (6) and method. The super-resolution imaging system (1, 41, 51) includes an illumination system (A) and an imaging system (B). The illumination system (A) outputs excitation light to irradiate a biological sample to generate excited light, and the imaging system (B) collects and records the excited light to generate an excited light image. The illumination system (A) includes an excitation light source (10, 10a) and a structured light generation and modulation device (11, 11a). The excitation light source (10, 10a) outputs the excitation light, and the structured light generation and modulation device (11, 11a) modulates the excitation light into structured light to irradiate the biological sample to generate the excited light.
    Type: Application
    Filed: March 9, 2020
    Publication date: March 14, 2024
    Inventors: JIELEI NI, MING NI, FAN ZHOU, ZEYU SU, KE JI, DONG WEI, MENGZHE SHEN, YUANQING LIANG, MEI LI, XUN XU
  • Publication number: 20230338526
    Abstract: Disclosed are anti-CD20 antibody formulations and use of anti-CD20 antibodies for the treatment of CD20 positive diseases, such as methods of using anti-CD20 antibodies for treating CD20 positive diseases, such as neuromyelitis optica spectrum disorders (NMOSD), non-Hodgkin's lymphoma (NHL), multiple sclerosis (MS), immune thrombocytopenia (ITP), rheumatoid arthritis (RA), Wegener's granulomatosis (WG), microscopic polyangiitis (MPA), lupus nephritis, systemic lupus erythematosus and chronic lymphocytic leukemia (CLL).
    Type: Application
    Filed: October 12, 2020
    Publication date: October 26, 2023
    Inventors: Yanyu CHEN, Yong WU, Yuanqing ZHOU, Chao QIN, Cuizhen XIAO, Zhihao WU, Dandan HUANG, Yujie LIU, Shengwu WANG, Cuihua LIU, Yunpeng QI, Jin-Chen YU, Li ZHANG, Shengfeng LI
  • Publication number: 20230203169
    Abstract: The present invention, in the field of bioengineering and biotechnology, relates to a method for preparing a recombinant antibody with a unique glycan profile produced by a genome-edited CHO host cell. Specifically, according to a method of the present invention, the TALEN technology is used to edit the FUT8 gene in CHO cells that have been adapted for serum-free suspension growth. The edited CHO host cells can produce recombinant antibodies with a unique glycan profile. The unique glycan profile can be characterized by non-fucosylated N-linked oligosaccharide chains of the antibodies, extremely low N-glycosylation heterogeneity and uniform carbohydrate chains. The antibody prepared by the method of the invention exhibit significantly increased ADCC and greater stability.
    Type: Application
    Filed: October 28, 2022
    Publication date: June 29, 2023
    Inventors: Chao Qin, Yuanqing Zhou, Cuizhen Xiao
  • Patent number: 11505609
    Abstract: The present invention, in the field of bioengineering and biotechnology, relates to a method for preparing a recombinant antibody with a unique glycan profile produced by a genome-edited CHO host cell. Specifically, according to a method of the present invention, the TALEN technology is used to edit the FUT8 gene in CHO cells that have been adapted for serum-free suspension growth. The edited CHO host cells can produce recombinant antibodies with a unique glycan profile. The unique glycan profile can be characterized by non-fucosylated N-linked oligosaccharide chains of the antibodies, extremely low N-glycosylation heterogeneity and uniform carbohydrate chains. The antibody prepared by the method of the invention exhibit significantly increased ADCC and greater stability.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: November 22, 2022
    Assignee: Bio-Thera Solutions, Ltd.
    Inventors: Chao Qin, Yuanqing Zhou, Cuizhen Xiao
  • Patent number: 10812599
    Abstract: A method and a system for creating a virtual non-volatile storage medium, and a management system. The method is: receiving, by a CPU, a creation request message that is sent by a client and that is for creating a virtual non-volatile storage medium corresponding to a physical non-volatile storage medium, where the creation request message carries a blade server identifier; forwarding, by the CPU, the creation request message to a target blade server identified by the blade server identifier; and receiving, by the CPU, attribute information sent by the target blade server, and sending the attribute information to the client, such that the client creates, according to the attribute information, a virtual non-volatile storage medium that can be uniquely accessed by the target blade server.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: October 20, 2020
    Assignee: Huawei Technologies Co., Ltd.
    Inventor: Yuanqing Zhou
  • Publication number: 20200199236
    Abstract: The present invention, in the field of bioengineering and biotechnology, relates to a method for preparing a recombinant antibody with a unique glycan profile produced by a genome-edited CHO host cell. Specifically, according to a method of the present invention, the TALEN technology is used to edit the FUT8 gene in CHO cells that have been adapted for serum-free suspension growth. The edited CHO host cells can produce recombinant antibodies with a unique glycan profile. The unique glycan profile can be characterized by non-fucosylated N-linked oligosaccharide chains of the antibodies, extremely low N-glycosylation heterogeneity and uniform carbohydrate chains. The antibody prepared by the method of the invention exhibit significantly increased ADCC and greater stability.
    Type: Application
    Filed: August 10, 2018
    Publication date: June 25, 2020
    Inventors: Chao QIN, Yuanqing ZHOU, Cuizhen XIAO
  • Publication number: 20170302742
    Abstract: A method and a system for creating a virtual non-volatile storage medium, and a management system. The method is: receiving, by a CPU, a creation request message that is sent by a client and that is for creating a virtual non-volatile storage medium corresponding to a physical non-volatile storage medium, where the creation request message carries a blade server identifier; forwarding, by the CPU, the creation request message to a target blade server identified by the blade server identifier; and receiving, by the CPU, attribute information sent by the target blade server, and sending the attribute information to the client, such that the client creates, according to the attribute information, a virtual non-volatile storage medium that can be uniquely accessed by the target blade server.
    Type: Application
    Filed: June 30, 2017
    Publication date: October 19, 2017
    Inventor: Yuanqing Zhou