Abstract: An atrial septal defect occluder, including: a body (100, 510), including two disk surfaces arranged opposite to each other and provided with a through hole (130) along an axial direction of the body (100, 510); and a blocking assembly, including an openable choke film (200) or elastic body (520), the blocking assembly being in contact with the body (100, 510), wherein when the blocking assembly is in a closed state, the blocking assembly impedes liquid from flowing in the through hole (130), and when the blocking assembly is in an open state, the blocking effect is weakened or even eliminated, thus allowing a minimally invasive interventional device to pass through the occluder by means of the through hole (130).

Abstract: The present invention provides a valved vascular prosthesis and a manufacturing method thereof. The valved vascular prosthesis, comprising an artificial blood vessel and a valve disposed inside for obstruction; the valve is in a skirt state extending toward the centerline of the artificial blood vessel; the valve is made by sewing a tubular vascular material on the artificial blood vessel; one end of the vascular material is connected to the artificial blood vessel along its radial direction, and the other end is a free end; the entire tubular body of the vascular material is sewed on the artificial blood vessel by a plurality of sutures; the sutures are radially parallel to the tubular body of the vascular material, and are arranged at intervals along the circumference of the tubular body of the vascular material. The valved vascular prosthesis of the present invention adopts suture of a polymer material and an artificial blood vessel.