Patents by Inventor Yuanyuan Chu

Yuanyuan Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusion protein comprising a Caspase domain and a nuclear hormone receptor binding domain and methods and uses thereof
    Patent number: 8530168
    Abstract: The present invention relates to a fusion protein comprising a Caspase domain or a functionally active variant thereof and a ligand binding domain of a nuclear hormone receptor, a nucleic acid coding for the fusion protein, a vector or cell comprising the nucleic acid, a method of producing the fusion protein, a non-human transgenic animal containing the nucleic acid, the use of the fusion protein for ligand-mediated induction of apoptosis of a cell, or for studying the function of a cell, tissue and/or organ or the use of a transgenic organism for studying the function of a cell at various developmental stages or as a disease model, a method for inducing apoptosis of a cell expressing a fusion protein or for identifying a ligand, or a medicament comprising a fusion protein, the nucleic acid, the vector or the cell, particularly for the treatment of cancer or for or after transplantation, particularly as safety mechanism.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: September 10, 2013
    Assignee: Helmholtz Zentrum Munich Deutsches Forschungszentrum fuer Gesundheit und Umwelt (GmbH)
    Inventors: Yuanyuan Chu, Ralf Kuehn, Wolfgang Wurst
  • FUSION PROTEIN COMPRISING A CASPASE DOMAIN AND A NUCLEAR HORMONE RECEPTOR BINDING DOMAIN AND METHODS AND USES THEREOF
    Publication number: 20110023137
    Abstract: The present invention relates to a fusion protein comprising a Caspase domain or a functionally active variant thereof and a ligand binding domain of a nuclear hormone receptor, a nucleic acid coding for the fusion protein, a vector or cell comprising the nucleic acid, a method of producing the fusion protein, a non-human transgenic animal containing the nucleic acid, the use of the fusion protein for ligand-mediated induction of apoptosis of a cell, or for studying the function of a cell, tissue and/or organ or the use of a transgenic organism for studying the function of a cell at various developmental stages or as a disease model, a method for inducing apoptosis of a cell expressing a fusion protein or for identifying a ligand, or a medicament comprising a fusion protein, the nucleic acid, the vector or the cell, particularly for the treatment of cancer or for or after transplantation, particularly as safety mechanism.
    Type: Application
    Filed: June 20, 2008
    Publication date: January 27, 2011
    Applicant: HELMHOLLZ ZENLRUM MUNICH DEULSCHES FORSCHUNG FUER GESUNDHEIT AND UNWELT
    Inventors: Yuanyuan Chu, Ralf Kuehn, Wolfgang Wurst