Abstract: A power tool includes a functional piece; an electric motor; a power supply device for supplying power to the electric motor; a parameter detection device configured to acquire multiple operating parameters of the electric motor and/or the power supply device; and a controller connected to the parameter detection device and configured to control running of the electric motor. The controller is configured to detect whether the multiple operating parameters satisfy policy switching conditions corresponding to the multiple operating parameters; in the case where any operating parameter of the multiple operating parameters satisfies a policy switching condition corresponding to the any operating parameter, control the electric motor by using a first electric motor control policy; and in the case where none of the multiple operating parameters satisfy the policy switching conditions corresponding to the multiple operating parameters, control the electric motor by using a second electric motor control policy.

Abstract: A PEGylated rapamycin compound and a preparation method therefor and an application thereof. The compound is represented by Formula (I), wherein n is 10-150. The preparation method is as follows: mPEG-COOH is dissolved in an organic solvent, catalysts EDC·HCl and DMAP, and RAPA are added, and the reaction is performed by stirring at 0-40° C. in the dark. An application of the compound and pharmaceutical preparations thereof in the preparation of a drug for reducing immune response can effectively inhibit the production of anti-drug antibodies of biological drugs such as urate oxidase, has good clinical application prospects, and is especially suitable to be prepared into a nano-drug.

Abstract: The present application provides a pole piece forming apparatus, which may include an incoming structure, a slitter, a plurality of winders and a wrinkle remover. The incoming structure may provide a master pole piece. The slitter may slit the master pole piece into a plurality of pole pieces. The winders may pull the transport of the pole pieces, respective winding devices may wind one corresponding pole piece, and the slitter may be disposed between the incoming structure and the winders. The wrinkle remover may be arranged between the slitter and the winders. The wrinkle remover may include a first roller and a second roller that may be provided opposite to each other, the first roller may include a first rolling part, and the first rolling part and the second roller may be used for rolling an edge of a slitting edge of the pole piece.

Abstract: Transdermal delivery peptides for the treatment of skin diseases and/or facilitation or enhancement of transdermal delivery of pharmaceutically active agents are provided. Compositions comprising the transdermal delivery peptides and methods of therapeutic use, including the improvement of transdermal delivery of drugs or other pharmaceutically active agents, are also disclosed. Nucleic acids, expression vectors, and methods of their use, which encode the transdermal delivery peptides are disclosed. Methods are also provided for in vivo phage display for identifying further peptides with enhanced transdermal delivery capability.

Abstract: Transdermal delivery peptides for the treatment of skin diseases and/or facilitation or enhancement of transdermal delivery of pharmaceutically active agents are provided. Compositions comprising the transdermal delivery peptides and methods of therapeutic use, including the improvement of transdermal delivery of drugs or other pharmaceutically active agents, are also disclosed. Nucleic acids, expression vectors, and methods of their use, which encode the transdermal delivery peptides are disclosed. Methods are also provided for in vivo phage display for identifying further peptides with enhanced transdermal delivery capability.