Patents by Inventor Yuanzhi LAO

Yuanzhi LAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170035824
    Abstract: Disclosed is a natural compound, Oblongifolin C, isolated from a natural plant comprising Garcinia species such as Garcinia yunnanesis Hu, for its effects of anti-migration and anti-invasion against cancer and its use as an anticancer drug. The treated cancers comprise cervical cancers and esophageal cancers. The cancer treatment comprises inhibition of cancer metastasis and inhibition of autophagic flux.
    Type: Application
    Filed: October 19, 2016
    Publication date: February 9, 2017
    Inventors: Hongxi XU, Yuanzhi LAO, Hongsheng TAN, Naihan XU, Xiaoyu WANG, Kaixian CHEN, Zhaoxiang BIAN, Dajian YANG, Shilin CHEN, Aiping LU, Albert Sun Chi CHAN
  • Patent number: 9408811
    Abstract: Prostate cancer is the most commonly diagnosed cancer in males and one of the leading causes of cancer death. Although treatment options have increased for some patients, overall progress has been modest. Thus, there is a great need to develop new treatments. This invention relates to a method for treating cancer comprising using an anti-cancer compound of formula (I): More particularly, it relates to said anti-prostate cancer compound that can be isolated from Garcinia esculenta or chemically synthesized and its specific anticancer/antitumor activity. The invention has a specific application in treating human prostate cancer.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: August 9, 2016
    Assignee: Hong Kong Baptist University
    Inventors: Hongxi Xu, Xin Li, Hong Zhang, Yuanzhi Lao, Hongsheng Tan, Xiaoyu Wang, Kaixian Chen, Zhaoxiang Bian, Dajian Yang, Shilin Chen, Aiping Lu, Albert Sun Chi Chan
  • Patent number: 9339488
    Abstract: Cervical cancer is one of the most common malignancies and is associated with a dismal prognosis. The most common therapeutic option for cervical cancer consists of surgery in early stages, and chemotherapy or radiotherapy in more advanced stages of the disease. Although treatment options have increased for some patients, overall progress has been modest. This invention relates to a method for treating cancer comprising administering an anti-cancer compound. More particularly, the present invention relates to an anti-cervical-cancer compound for treating human cervical cancer and tumor.
    Type: Grant
    Filed: July 31, 2014
    Date of Patent: May 17, 2016
    Assignee: HONG KONG BAPTIST UNIVERSITY
    Inventors: Hongxi Xu, Hong Zhang, Yuanzhi Lao, Xiaoyu Wang, Kaixian Chen, Dajian Yang, Shilin Chen, Chengyuan Lin, Zhaoxiang Bian, Aiping Lu, Albert Sun Chi Chan
  • Publication number: 20150231090
    Abstract: The present invention provides composition for treating cancer comprising polyprenylated acylphloroglucinol (PPAP) compound. The present invention also provides a composition comprising Guttiferone K for treating esophageal cancer and liver cancer. The present invention further provides a method of using said compound for inhibiting cancer metastasis.
    Type: Application
    Filed: May 1, 2015
    Publication date: August 20, 2015
    Inventors: Hongxi XU, Kaikai SHEN, Yuanzhi LAO, Hongsheng TAN, Kaixian CHEN, Dajian YANG, Shilin CHEN, Zhaoxiang BIAN, Chengyuan LIN, Aiping LU, Albert Sun Chi CHAN
  • Publication number: 20150038569
    Abstract: Cervical cancer is one of the most common malignancies and is associated with a dismal prognosis. The most common therapeutic option for cervical cancer consists of surgery in early stages, and chemotherapy or radiotherapy in more advanced stages of the disease. Although treatment options have increased for some patients, overall progress has been modest. This invention relates to a method for treating cancer comprising administering an anti-cancer compound. More particularly, the present invention relates to an anti-cervical-cancer compound for treating human cervical cancer and tumor.
    Type: Application
    Filed: July 31, 2014
    Publication date: February 5, 2015
    Inventors: Hongxi XU, Hong ZHANG, Yuanzhi LAO, Xiaoyu WANG, Kaixian CHEN, Dajian YANG, Shilin CHEN, Chengyuan LIN, Zhaoxiang BIAN, Aiping LU, Albert Sun Chi CHAN
  • Publication number: 20150025155
    Abstract: Prostate cancer is the most commonly diagnosed cancer in males and one of the leading causes of cancer death. Although treatment options have increased for some patients, overall progress has been modest. Thus, there is a great need to develop new treatments. This invention relates to a method for treating cancer comprising using an anti-cancer compound. More particularly, it relates to an anti-prostate cancer compound that can be isolated from Garcinia esculenta or chemically synthesized and its specific anticancer/antitumor activity. The invention has a specific application in treating human prostate cancer.
    Type: Application
    Filed: July 17, 2014
    Publication date: January 22, 2015
    Inventors: Hongxi XU, Xin LI, Hong ZHANG, Yuanzhi LAO, Hongsheng TAN, Xiaoyu WANG, Kaixian CHEN, Zhaoxiang BIAN, Dajian YANG, Shilin CHEN, Aiping LU, Albert Sun Chi CHAN
  • Publication number: 20150011646
    Abstract: This invention is related to compounds isolated from various Garcinia species and method of treating cancer. The present invention provides composition for treating cancer comprising polyprenylated acylphloroglucinol (PPAP) compound. The present invention also provides a composition comprising Guttiferone K for treating esophageal cancer.
    Type: Application
    Filed: January 8, 2014
    Publication date: January 8, 2015
    Applicant: Hong Kong Baptist University
    Inventors: Hongxi XU, Yuanzhi LAO, Zhichao XI, Hongsheng TAN, Kaixian CHEN, Zhaoxiang BIAN, Dajian YANG, Shilin CHEN, Aiping LU, Albert Sun Chi CHAN
  • Publication number: 20140235877
    Abstract: The present invention provides two compounds, namely Compound A and B, as the potential anticancer drug, and a composition comprising said Compound A and/or B for treating cancer or tumor related diseases. The present invention also relates to methods of preparing the compounds from a natural source and a composition comprising the compounds, and using the same for treating cancer or tumor related diseases.
    Type: Application
    Filed: March 31, 2014
    Publication date: August 21, 2014
    Applicant: Hong Kong Baptist University
    Inventors: Hongxi XU, Zhengxiang XIA, Yuanzhi LAO, Hongsheng TAN, Zhaoxiang BIAN, Dajian YANG, Shilin CHEN, Kaixian CHEN, Albert Sun-Chi CHAN
  • Publication number: 20140194499
    Abstract: Two novel polyprenylated benzoylphloroglucinol derivatives, garciesculentones A and C, are disclosed in the present invention. Garciesculentones A and C exhibit cytotoxicity and/or antimigration effect against various cancer cell lines. The experimental results of the present invention suggest that Garciesculentones A and C are useful for developing into anticancer drugs.
    Type: Application
    Filed: January 9, 2014
    Publication date: July 10, 2014
    Applicant: Hong Kong Baptist University
    Inventors: Hongxi XU, Hong ZHANG, Yuanzhi LAO, Dandan ZHANG, Kaixian CHEN, Zhaoxiang BIAN, Chengyuan LIN, Dajian YANG, Shilin CHEN, Aiping LU, Albert Sun Chi CHAN
  • Publication number: 20140194528
    Abstract: The present invention relates to a synthetic compound and its therapeutic uses.
    Type: Application
    Filed: January 8, 2014
    Publication date: July 10, 2014
    Applicant: Hong Kong Baptist University
    Inventors: Hongxi XU, Yunhui SHEN, Yuanzhi LAO, Kaixian CHEN, Dajian YANG, Shilin CHEN, Zhaoxiang BIAN, Aiping LU, Albert Sun Chi CHAN, Chengyuan LIN
  • Publication number: 20140194530
    Abstract: Disclosed is a natural compound, Oblongifolin C, isolated from a natural plant comprising Garcinia species such as Garcinia yunnanesis Hu, for its effects of anti-migration and anti-invasion against cancer and its use as an anticancer drug. The treated cancers comprise cervical cancers and esophageal cancers. The cancer treatment comprises inhibition of cancer metastasis and inhibition of autophagic flux.
    Type: Application
    Filed: January 9, 2014
    Publication date: July 10, 2014
    Applicant: Hong Kong Baptist University
    Inventors: Hongxi Xu, Yuanzhi Lao, Hongsheng Tan, Naihan Xu, Xiaoyu Wang, Zhenyan Liu, Kaixian Chen, Zhaoxiang Bian, Dajian Yang, Shilin Chen, Aiping Lu, Albert Sun Chi Chan