Abstract: A method for the separation of at least one glyco-containing entity, in which method said entity or entities dissolved/suspended in a liquid is/are contacted with a polymer, which has boronic acid covalently coupled to said polymer and previously has been equilibrated with said liquid, to form a boronate-glyco-complex whereafter the glyco-containing entity or entities is/are released from the boronate-modified polymer is disclosed, wherein said liquid contains one or more substances capable of forming complexes with boronic acids/boronate anions, which complexes are weaker than the boronate-glyco-complex but stronger than complexes formed by interactions others than glyco-boronate.