Patents by Inventor Yucai YAO

Yucai YAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indolizine compounds, preparation method and use thereof
    Patent number: 11661421
    Abstract: The invention provides an indolizine compound represented by formula I or a pharmaceutically acceptable salt thereof, a preparation method and a use thereof. The indolizine compound has an inhibitory effect on wild-type and/or mutant EZH2 or EZH1, and is expected to be developed into a novel drug for anti-tumor or for the treatment of autoimmune diseases.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: May 30, 2023
    Assignee: HAIHE BIOPHARMA CO., LTD.
    Inventors: Xuxing Chen, Yi Chen, Ying Huang, Meiyu Geng, Qiong Zhang, Jian Ding, Yucai Yao, Qianqian Shen, Yanyan Shen
  • Pyrido five-element aromatic ring compound, preparation method therefor and use thereof
    Patent number: 10968215
    Abstract: The present invention provides a pyrido five-element aromatic ring compound, and a preparation method therefor and a use thereof. The compound provided in the present invention has an inhibitory effect on wild-type and/or mutant EZH2, and is well positioned to become a novel anti-tumor drug or a drug for the treatment of autoimmune diseases.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: April 6, 2021
    Assignees: SHANGHAI HAIHE PHARMACEUTICAL CO., LTD., SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
    Inventors: Xuxing Chen, Meiyu Geng, Lei Jiang, Yi Chen, Jianhua Cao, Qingyun Jiang, Qianqian Shen, Jian Ding, Yucai Yao, Zhao Zhao, Yuanfang Xiong
  • INDOLIZINE COMPOUNDS, PREPARATION METHOD AND USE THEREOF
    Publication number: 20200399270
    Abstract: The invention provides an indolizine compound represented by formula I or a pharmaceutically acceptable salt thereof, a preparation method and a use thereof. The indolizine compound has an inhibitory effect on wild-type and/or mutant EZH2 or EZH1, and is expected to be developed into a novel drug for anti-tumor or for the treatment of autoimmune diseases.
    Type: Application
    Filed: March 5, 2019
    Publication date: December 24, 2020
    Inventors: Xuxing Chen, Yi Chen, Ying Huang, Meiyu Geng, Qiong Zhang, Jian Ding, Yucai Yao, Qianqian Shen, Yanyan Shen
  • PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20190211010
    Abstract: The present invention provides a pyrido five-element aromatic ring compound, and a preparation method therefor and a use thereof. The compound provided in the present invention has an inhibitory effect on wild-type and/or mutant EZH2, and is well positioned to become a novel anti-tumor drug or a drug for the treatment of autoimmune diseases.
    Type: Application
    Filed: September 6, 2017
    Publication date: July 11, 2019
    Inventors: Xuxing CHEN, Meiyu GENG, Lei JIANG, Yi CHEN, Jianhua CAO, Qingyun JIANG, Qianqian SHEN, Jian DING, Yucai YAO, Zhao ZHAO, Yuanfang XIONG