Patents by Inventor Yuchen Bai

Yuchen Bai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND REAGENTS FOR ANALYSING NUCLEIC ACIDS FROM SINGLE CELLS
    Publication number: 20210348213
    Abstract: The present invention relates to a partition library which comprises a plurality of partitions which are useful for the analysis of the transcriptional response of a CAR to a target antigen. Further, the present invention relates to assays for the analysis of the transcriptional response of a CAR to a target antigen. The present invention also relates to kits comprising the plurality of partitions.
    Type: Application
    Filed: October 10, 2019
    Publication date: November 11, 2021
    Inventors: Biao Ma, Preeta Datta, Yuchen Bai, Shimobi Onuoha, Martin Pulé
  • METHODS AND REAGENT FOR ANALYSING NUCLEIC ACIDS FROM INDIVIDUAL CELLS
    Publication number: 20210332411
    Abstract: The present disclosure relates to a bispecific reagent and a detection agent which are useful for the identification of an antibody-producing cell which produces an antibody that binds specifically to a target antigen. Further, the present disclosure relates to an assay for the identification of an antibody-producing cell which produces an antibody that binds specifically to a target antigen. The present disclosure also relates to kits comprising the bispecific reagent and the detection agent.
    Type: Application
    Filed: October 10, 2019
    Publication date: October 28, 2021
    Inventors: Biao Ma, Leo Kassimatis, Rosalind Gealy, Yuchen Bai, Shimobi Onuoha, Martin Pulé
  • IDENTIFICATION OF OLIGOADENYLATE SYNTHETASE-LIKE GENES
    Publication number: 20080081780
    Abstract: The present invention relates to compositions and methods for modulating conception in animals. More particularly, the composition modulates mRNA degradation during gametogenesis and early development. Yet further, the present invention relates to pharmaceutical compositions and methods for modulating diseases of the reproductive organs, such as hyperproliferative diseases.
    Type: Application
    Filed: June 17, 2007
    Publication date: April 3, 2008
    Inventors: Martin Matzuk, Yuchen Bai, Wei Yan
  • Identification of oligoadenylate synthetase-like genes
    Patent number: 7232678
    Abstract: The present invention relates to compositions and methods for modulating conception in animals. More particularly, the composition modulates mRNA degradation during gametogenesis and early development. Yet further, the present invention relates to pharmaceutical compositions and methods for modulating diseases of the reproductive organs, such as hyperproliferative diseases.
    Type: Grant
    Filed: May 16, 2003
    Date of Patent: June 19, 2007
    Assignees: Wyeth, Baylor College of Medicine
    Inventors: Martin M. Matzuk, Yuchen Bai, Wei Yan
  • Contraceptive targets
    Publication number: 20060079674
    Abstract: The present invention relates generally to ovary-specific genes (O1-180, O1-184 and O1-236) and the proteins they encode. Also provided are methods for detecting cell proliferative or degenerative disorders in reproductive tissues. Yet further, the invention provides methods for scrounge of compounds that interact and/or modulate the expression or activity of the ovary-specific genes. These compounds are possible contraceptive agents and/or fertility agents.
    Type: Application
    Filed: October 14, 2004
    Publication date: April 13, 2006
    Inventors: Martin Matzuk, Yuchen Bai, Pei Wang, Xuemei Wu
  • Ovary-specific genes and proteins
    Publication number: 20040254132
    Abstract: The present invention relates generally to ovary-specific genes (O1-180, O1-184 and O1-236) and the proteins they encode. Also provided are methods for detecting cell proliferative or degenerative disorders in reproductive tissues. Yet further, the invention provides methods for screeing of compounds that interact and/or modulate the expression or activity of the ovary-specific genes. These compounds are possible contraceptive agents and/or fertility agents.
    Type: Application
    Filed: August 5, 2004
    Publication date: December 16, 2004
    Inventors: Martin M. Matzuk, Xuemei Wu, Pei Wang, Yuchen Bai
  • Identification of oligoadenylate synthetase-like genes
    Publication number: 20030235575
    Abstract: The present invention relates to compositions and methods for modulating conception in animals. More particularly, the composition modulates mRNA degradation during gametogenesis and early development. Yet further, the present invention relates to pharmaceutical compositions and methods for modulating diseases of the reproductive organs, such as hyperproliferative diseases.
    Type: Application
    Filed: May 16, 2003
    Publication date: December 25, 2003
    Applicants: WYETH, Baylor College of Medicine
    Inventors: Martin M. Matzuk, Yuchen Bai, Wei Yan