Patents by Inventor Yucheng Tang
Yucheng Tang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240085858Abstract: The present invention discloses a smart watch, including a housing with a mounting cavity, a top cover that covers the housing, a movement in the mounting cavity, a watch dial for displaying time, a light emitting module, a shake sensing module, a tap sensing module, and an audio player. The light emitting module is configured to be turned on when the shake sensing module senses that the smart watch is shaken and turned off when the tap sensing module senses that the smart watch is tapped. The audio player is configured to be started when the smart watch is tapped or shaken. According to the present invention, when needing to turn on the light emitting module, a user only needs to shake the smart watch worn on his/her wrist, and when needing to turn off the light emitting module, the user only needs to tap the smart watch with his/her hand. Compared with the way of turning on the light emitting module by pressing a physical button, the smart watch is simpler and more convenient in operation.Type: ApplicationFiled: September 9, 2022Publication date: March 14, 2024Inventors: Yangde Li, Wenxuan Li, Mixin Tang, Yi Li, Yucheng Liang, Mingyang Cui
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Publication number: 20240075158Abstract: Provided are a complex of an anti-IL-4R antibody or an antigen-binding fragment thereof, and a medical use thereof. Specifically, provided are a complex of an antibody that specifically binds to IL-4R or an antigen-binding fragment thereof covalently linked to a toxin, a pharmaceutical composition comprising the complex, and a use thereof in the preparation of a drug for treating IL-4R-mediated diseases or disorders, especially a use in the preparation of an anti-cancer drug.Type: ApplicationFiled: December 22, 2021Publication date: March 7, 2024Inventors: Huan WANG, Yuan LIN, Yucheng TANG, Ke KE, Kan LIN, Cheng LIAO
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Publication number: 20240023927Abstract: For three-dimensional segmentation from two-dimensional intracardiac echocardiography imaging, the three-dimension segmentation is output by a machine-learnt multi-task generator. Rather than the brute force approach of training the generator from 2D ICE images to output a 2D segmentation, the generator is trained from 3D information, such as a sparse ICE volume assembled from the 2D ICE images. Where sufficient ground truth data is not available, computed tomography or magnetic resonance data may be used as the ground truth for the sample sparse ICE volumes. The generator is trained to output both the 3D segmentation and a complete volume (i.e., more voxels represented than in the sparse ICE volume). The 3D segmentation may be further used to project to 2D as an input with an ICE image to another network trained to output a 2D segmentation for the ICE image. Display of the 3D segmentation and/or 2D segmentation may guide ablation of tissue in the patient.Type: ApplicationFiled: September 29, 2023Publication date: January 25, 2024Inventors: Gareth Funka-Lea, Haofu Liao, Shaohua Kevin Zhou, Yefeng Zheng, Yucheng Tang
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Publication number: 20230382800Abstract: The invention provides a modified dolomite powder, a preparation method thereof, and a concrete. The modified dolomite powder is prepared from 98% to 99% of a dolomite powder, 0.2% to 0.5% of a chaotropic agent, 0.6% to 1.0% of a dihydrogen phosphate, and 0.2% to 0.5% of a capillary filler according to the mass percentage. The chaotropic agent is one or more of sodium sulfate, potassium sulfate, and ammonium sulfate. By promoting the dissolution of the surface of the dolomite powder, participating in the hydration reaction, and filling capillary pores, the triple modification solves the problems of bleeding, strength, and durability of the dolomite powder concrete in the related art. The obtained modified dolomite powder has good solubility and high chemical activity, and the prepared concrete has high strength and compactness, low porosity, and good durability.Type: ApplicationFiled: May 16, 2023Publication date: November 30, 2023Applicants: ANHUI ZHONGTIE ENGINEERING MATERIAL TECHNOLOGY CO., LTD., CHINA TIESIJU CIVIL ENGINEERING GROUP CO., LTD.Inventors: Jianwei Peng, Dongdong Fan, Hai Huang, Jie Tang, Chenghao Wu, Jianfeng Wen, Yucheng Tang, Chunsong Yu, Yitao Chen, Jianan Yao
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Patent number: 11806189Abstract: For three-dimensional segmentation from two-dimensional intracardiac echocardiography imaging, the three-dimension segmentation is output by a machine-learnt multi-task generator. Rather than the brute force approach of training the generator from 2D ICE images to output a 2D segmentation, the generator is trained from 3D information, such as a sparse ICE volume assembled from the 2D ICE images. Where sufficient ground truth data is not available, computed tomography or magnetic resonance data may be used as the ground truth for the sample sparse ICE volumes. The generator is trained to output both the 3D segmentation and a complete volume (i.e., more voxels represented than in the sparse ICE volume). The 3D segmentation may be further used to project to 2D as an input with an ICE image to another network trained to output a 2D segmentation for the ICE image. Display of the 3D segmentation and/or 2D segmentation may guide ablation of tissue in the patient.Type: GrantFiled: November 28, 2022Date of Patent: November 7, 2023Assignee: Siemens Medical Solutions USA, Inc.Inventors: Gareth Funka-Lea, Haofu Liao, Shaohua Kevin Zhou, Yefeng Zheng, Yucheng Tang
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Publication number: 20230113154Abstract: For three-dimensional segmentation from two-dimensional intracardiac echocardiography imaging, the three-dimension segmentation is output by a machine-learnt multi-task generator. Rather than the brute force approach of training the generator from 2D ICE images to output a 2D segmentation, the generator is trained from 3D information, such as a sparse ICE volume assembled from the 2D ICE images. Where sufficient ground truth data is not available, computed tomography or magnetic resonance data may be used as the ground truth for the sample sparse ICE volumes. The generator is trained to output both the 3D segmentation and a complete volume (i.e., more voxels represented than in the sparse ICE volume). The 3D segmentation may be further used to project to 2D as an input with an ICE image to another network trained to output a 2D segmentation for the ICE image. Display of the 3D segmentation and/or 2D segmentation may guide ablation of tissue in the patient.Type: ApplicationFiled: November 28, 2022Publication date: April 13, 2023Inventors: Gareth Funka-Lea, Haofu Liao, Shaohua Kevin Zhou, Yefeng Zheng, Yucheng Tang
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Publication number: 20230036451Abstract: Apparatuses, systems, and techniques are presented to predict annotations for objects in images. In at least one embodiment, one or more neural networks are used to help generate one or more segmentation boundaries of one or more objects within one or more digital images, wherein the one or more neural networks are to transform one or more representations of one or more portions of the one or more objects into one or more lower-dimensional representations of the one or more portions of the one or more objects.Type: ApplicationFiled: July 13, 2021Publication date: February 2, 2023Inventors: Ali Hatamizadeh, Daguang Xu, Dong Yang, Holger Reinhard Roth, Andriy Myronenko, Vishwesh Nath, Yucheng Tang
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Patent number: 11534136Abstract: For three-dimensional segmentation from two-dimensional intracardiac echocardiography imaging, the three-dimension segmentation is output by a machine-learnt multi-task generator. The machine-learnt multi-task generator is trained from 3D information, such as a sparse ICE volume assembled from the 2D ICE images. The machine-learnt multi-task generator is trained to output both the 3D segmentation and a complete volume. The 3D segmentation may be used to project to 2D as an input with an ICE image to another network trained to output a 2D segmentation for the ICE image. Display of the 3D segmentation and/or 2D segmentation may guide ablation of tissue in the patient.Type: GrantFiled: September 13, 2018Date of Patent: December 27, 2022Assignee: Siemens Medical Solutions USA, Inc.Inventors: Gareth Funka-Lea, Haofu Liao, Shaohua Kevin Zhou, Yefeng Zheng, Yucheng Tang
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Publication number: 20220143171Abstract: Provided are methods of generating an immune response to any of various antigens including foreign antigens such as infectious agent antigens. In general, the method comprises administering an expression vector encoding a transcription unit encoding a secretable fusion protein, the fusion protein containing the foreign antigen and CD40 ligand and also administering the encoded fusion protein. In another approach, an immune response to the foreign antigen is elicited using the encoded fusion protein without administering the vector. The invention methods may be used to immunize an individual against an infectious agent such as influenza virus. Methods of obtaining an immune response in older individuals also is described.Type: ApplicationFiled: August 2, 2021Publication date: May 12, 2022Inventors: Yucheng Tang, Albert B. Deisseroth
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Publication number: 20220097489Abstract: An air vent assembly for a vehicle interior is disclosed. The assembly may comprise an inner airflow guide, an outer airflow guide and a drive mechanism comprising an inner airflow mechanism to actuate the inner airflow guide and an outer airflow mechanism to actuate the outer airflow guide. The drive mechanism when operated in a first direction will actuate the inner airflow mechanism and when operated in a second direction will actuate the outer airflow mechanism. The drive mechanism may comprise a clutch mechanism to engage the inner airflow mechanism when operated in the first direction and to engage the outer airflow mechanism when operated in the second direction. The clutch mechanism may comprise a set of one-way bearings. The inner airflow guide may comprise a vertical blade set; the outer airflow guide may comprise a horizontal blade set. The drive mechanism is operated by a motor and rotating shaft.Type: ApplicationFiled: December 9, 2021Publication date: March 31, 2022Inventor: Yucheng TANG
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Patent number: 11077183Abstract: Provided are methods of generating an immune response to any of various antigens including foreign antigens such as infectious agent antigens. In general, the method comprises administering an expression vector encoding a transcription unit encoding a secretable fusion protein, the fusion protein containing the foreign antigen and CD40 ligand and also administering the encoded fusion protein. In another approach, an immune response to the foreign antigen is elicited using the encoded fusion protein without administering the vector. The invention methods may be used to immunize an individual against an infectious agent such as influenza virus. Methods of obtaining an immune response in older individuals also is described.Type: GrantFiled: December 29, 2016Date of Patent: August 3, 2021Assignee: MicroVAX, LLCInventors: Yucheng Tang, Albert B. Deisseroth
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Publication number: 20190261945Abstract: For three-dimensional segmentation from two-dimensional intracardiac echocardiography imaging, the three-dimension segmentation is output by a machine-learnt multi-task generator. Rather than the brute force approach of training the generator from 2D ICE images to output a 2D segmentation, the generator is trained from 3D information, such as a sparse ICE volume assembled from the 2D ICE images. Where sufficient ground truth data is not available, computed tomography or magnetic resonance data may be used as the ground truth for the sample sparse ICE volumes. The generator is trained to output both the 3D segmentation and a complete volume (i.e., more voxels represented than in the sparse ICE volume). The 3D segmentation may be further used to project to 2D as an input with an ICE image to another network trained to output a 2D segmentation for the ICE image. Display of the 3D segmentation and/or 2D segmentation may guide ablation of tissue in the patient.Type: ApplicationFiled: September 13, 2018Publication date: August 29, 2019Inventors: Gareth Funka-Lea, Haofu Liao, Shaohua Kevin Zhou, Yefeng Zheng, Yucheng Tang
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Patent number: 9757438Abstract: Provided are expression vectors for generating an immune response to a mucin. The vectors comprise a transcription unit encoding a secretable polypeptide, the polypeptide comprising a secretory signal, a mucin antigen and CD40 ligand. Also provided are methods of generating an immune response against cells expressing a mucin by administering an effective amount of the vector. Further provided are methods of generating an immune response against cancer cells expressing a mucin in an individual by administering an effective amount of the vector. Still further provided are methods of overcoming anergy to a mucin self antigen by administering an effective amount of the vector.Type: GrantFiled: July 19, 2016Date of Patent: September 12, 2017Assignee: MICROVAX, LLCInventors: Yucheng Tang, Albert Deisseroth
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Publication number: 20170182147Abstract: Provided are methods of generating an immune response to any of various antigens including foreign antigens such as infectious agent antigens. In general, the method comprises administering an expression vector encoding a transcription unit encoding a secretable fusion protein, the fusion protein containing the foreign antigen and CD40 ligand and also administering the encoded fusion protein. In another approach, an immune response to the foreign antigen is elicited using the encoded fusion protein without administering the vector. The invention methods may be used to immunize an individual against an infectious agent such as influenza virus. Methods of obtaining an immune response in older individuals also is described.Type: ApplicationFiled: December 29, 2016Publication date: June 29, 2017Inventors: Yucheng Tang, Albert B. Deisseroth
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Publication number: 20170014497Abstract: Provided are expression vectors for generating an immune response to a mucin. The vectors comprise a transcription unit encoding a secretable polypeptide, the polypeptide comprising a secretory signal, a mucin antigen and CD40 ligand. Also provided are methods of generating an immune response against cells expressing a mucin by administering an effective amount of the vector. Further provided are methods of generating an immune response against cancer cells expressing a mucin in an individual by administering an effective amount of the vector. Still further provided are methods of overcoming anergy to a mucin self antigen by administering an effective amount of the vector.Type: ApplicationFiled: July 19, 2016Publication date: January 19, 2017Inventors: Yucheng Tang, Albert Deisseroth
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Methods for generating immune responses to influenza antigens with a secretable CD40L fusion protein
Patent number: 9533036Abstract: Provided are methods of generating an immune response to any of various antigens including foreign antigens such as infectious agent antigens. In general, the method comprises administering an expression vector encoding a transcription unit encoding a secretable fusion protein, the fusion protein containing the foreign antigen and CD40 ligand and also administering the encoded fusion protein. In another approach, an immune response to the foreign antigen is elicited using the encoded fusion protein without administering the vector. The invention methods may be used to immunize an individual against an infectious agent such as influenza virus. Methods of obtaining an immune response in older individuals also is described.Type: GrantFiled: November 6, 2006Date of Patent: January 3, 2017Assignee: MicroVAX, LLCInventors: Yucheng Tang, Albert Deisseroth -
Patent number: 9402920Abstract: Provided are expression vectors for generating an immune response to a mucin. The vectors comprise a transcription unit encoding a secretable polypeptide, the polypeptide comprising a secretory signal, a mucin antigen and CD40 ligand. Also provided are methods of generating an immune response against cells expressing a mucin by administering an effective amount of the vector. Further provided are methods of generating an immune response against cancer cells expressing a mucin in an individual by administering an effective amount of the vector. Still further provided are methods of overcoming anergy to a mucin self antigen by administering an effective amount of the vector.Type: GrantFiled: April 18, 2014Date of Patent: August 2, 2016Assignee: MicroVAX, LLCInventors: Yucheng Tang, Albert Deisseroth
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Patent number: 9353167Abstract: Provided are methods of generating an immune response to an antigen. The method comprises priming an individual by administering an expression vector encoding the antigen. The vector comprises a transcription unit encoding a secretable fusion protein, the fusion protein containing an antigen and CD40 ligand. Administration of a fusion protein containing the antigen and CD40 ligand is used to enhance the immune response above that obtained by vector administration alone. The methods may be used to generate an immune response against cancer expressing a tumor antigen such as a mucin or human papilloma viral tumor antigen and to generate an immune response against an infectious agent. Also provided is a method for simultaneously producing the expression vector and the fusion protein.Type: GrantFiled: September 5, 2014Date of Patent: May 31, 2016Assignee: MicroVAX, LLCInventors: Albert B. Deisseroth, Yucheng Tang, Wei-Wei Zhang, Xiang-Ming Fang
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Publication number: 20150064209Abstract: Provided are methods of generating an immune response to an antigen. The method comprises priming an individual by administering an expression vector encoding the antigen. The vector comprises a transcription unit encoding a secretable fusion protein, the fusion protein containing an antigen and CD40 ligand. Administration of a fusion protein containing the antigen and CD40 ligand is used to enhance the immune response above that obtained by vector administration alone. The methods may be used to generate an immune response against cancer expressing a tumor antigen such as a mucin or human papilloma viral tumor antigen and to generate an immune response against an infectious agent. Also provided is a method for simultaneously producing the expression vector and the fusion protein.Type: ApplicationFiled: September 5, 2014Publication date: March 5, 2015Inventors: Albert B. Deisseroth, Yucheng Tang, Wei-Wei Zhang, Xiang-Ming Fang
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Publication number: 20140322301Abstract: Provided are expression vectors for generating an immune response to a mucin. The vectors comprise a transcription unit encoding a secretable polypeptide, the polypeptide comprising a secretory signal, a mucin antigen and CD40 ligand. Also provided are methods of generating an immune response against cells expressing a mucin by administering an effective amount of the vector. Further provided are methods of generating an immune response against cancer cells expressing a mucin in an individual by administering an effective amount of the vector. Still further provided are methods of overcoming anergy to a mucin self antigen by administering an effective amount of the vector.Type: ApplicationFiled: April 18, 2014Publication date: October 30, 2014Applicant: MicroVAX, LLCInventors: Yucheng Tang, Albert Deisseroth