Abstract: The present application provides methods of treating PI3K? related disorders using compounds of Formula I: or pharmaceutically acceptable salts thereof.

Abstract: A method for preparing an AlN based template having a Si substrate and a method for preparing a GaN based epitaxial structure having a Si substrate are provided. The method for preparing the AlN based template having the Si substrate, which includes: providing the Si substrate; growing an AlN nucleation layer on the Si substrate; and introducing an ion passing through the AlN nucleation layer and into the Si substrate. After the AlN nucleation layer is prepared on the Si substrate, the ions are introduced into the Si substrate and the AlN nucleation layer through the AlN nucleation layer. In this way, types of the introduced ions can be expanded. In addition, a carrier concentration at an interface between the Si substrate and the AlN nucleation layer and a carrier concentration in the AlN nucleation layer can also be reduced.

Abstract: A video processing method includes determining, for a conversion between a block of a video and a bitstream representation of the video, that an output value from an inverse secondary transform with a reduced dimension (e.g., an inverse low frequency non-separable transform) is constrained within a range of [min, max] inclusively. The inverse secondary transform is applicable to the block between a de-quantization step and an inverse primary transform. The reduced dimension is reduced from a dimension of the block, and min and max are integer values. The method also includes performing the conversion based on the determining.

Abstract: Methods, systems, apparatus for media processing are described. One example method of digital media processing includes determining, for a conversion between visual media data and a bitstream of the visual media data, how to apply one or more convolutional neural network filters to at least some samples of a video unit of the visual media data according to a rule; and performing the conversion based on the determining.

Abstract: A method for measuring an electron nonextensive parameter of a plasma by using nonextensive statistical mechanics and electric probe is provided. The plasma is described by the nonextensive statistical mechanics and establishes a nonextensive single electric probe theory on the basis of this. The electron nonextensive parameter have been measured which cannot be measured by traditional single probe, and obtained more accurate electron temperature, plasma potential, electron density and floating potential than traditional single probe. The nonextensive electric probe plays a role in plasma diagnosis, which will measure the nonextensivity of plasma and improve the diagnostic accuracy of other plasma parameters.

Abstract: A metastable state detection device and method, and an ADC circuit are disclosed. The metastable state detection device includes: a delay unit which is configured to receive a synchronization signal and delay the synchronization signal based on preset step delay values; a first flip-flop unit including a first clock input terminal, a first data input terminal and a first data output terminal, wherein the first clock input terminal is configured to receive a clock signal; the first data input terminal is configured to receive the delayed synchronization signal; a second flip-flop unit including a second clock input terminal, a second data input terminal and a second data output terminal; a processing module connected to the second data output terminal, which is configured to receive a target clock signal and detect a metastable state of the first flip-flop unit according to the target clock signal.

Abstract: The present disclosure provides novel and improved IL-15 fusion proteins for use in the treatment of cancer and other disorders. In various embodiments, the fusion proteins of the invention have two functional domains: an IL-15/IL-15R?Sushi domain (also referred to herein as an “IL-15/IL-15R?Sushi complex”) and an Fc domain, each of which can take different forms, and configured such that the IL-15 is fused to the C-terminal of the Fc domain and co-expressed and non-covalently complexed with IL-15R?Sushi. Importantly, the fusions proteins of the present invention address several of the limitations observed with the IL-15 therapeutics evaluated to date; specifically, the fusion proteins demonstrate extended the half-life of IL-15 in vivo, and demonstrate superior preclinical activity compared to rIL-15 or related cytokine therapeutics.

Abstract: An electrolyte additive containing a silyl-group compound useful for reducing battery resistance and improving high-temperature performance; an electrolyte containing the silyl-group compound additive; and an electrochemical energy storage device containing the electrolyte are disclosed.

Abstract: The retrievable packer system includes a packer mandrel, a lock ring, an upper cone, a lower cone, a slip device, a retrieval mandrel, and a plurality of push rods. The lock ring is attached to the packer mandrel, followed by the upper cone, the slip device, the lower cone, and the retrieval mandrel. The lower cone has lower cone rod channels, and the push rods anchored on the retrieval mandrel slide through respective channels toward the upper cone. The packer system is run into the borehole with each rod in the first position relative to a tip end of the lower cone and the slip device in the run-in position. The packer system is set and can be locked at a location in the borehole. Each push rod can push the upper cone to return the slip device to the run-in position for retrieval of the packer system.

Abstract: A brain-computer interface device includes a plurality of pre-amplifiers are configured to amplify physiological signals corresponding to channels to output amplified signals; a multiplexer is configured to output, according to a control signal and a clock signal, the amplified signals; an analog-to-digital converter is configured to convert, according to the clock signal including clocks, the output of the multiplexer into a digital signal including a plurality of digital values corresponding to the clocks, wherein each of the digital values includes bit values; a memory is configured to store the digital signal; and a processor s configured to: add a header corresponding to one channel to each of the digital values according to the clock signal; and delete bit values of higher bits of each of the digital values corresponding to the same channel that are the same as those of a previous digital value, to output a compressed signal.

Abstract: The disclosed technology generally relates to quartz crystal devices and more particularly to quartz crystal devices configured to vibrate in torsional mode. In one aspect, a quartz crystal device configured for temperature sensing comprises a fork-shaped quartz crystal comprising a pair of elongate tines laterally extending from a base region in a horizontal lengthwise direction of the fork-shaped quartz crystal. Each of the tines has formed on one or both of opposing sides thereof a vertically protruding line structure laterally elongated in the horizontal lengthwise direction. The quartz crystal device further comprises a first electrode and a second electrode formed on the one or both of the opposing sides of each of the tines and configured such that, when an electrical bias is applied between the first and second electrodes, the fork-shaped quartz crystal vibrates in a torsional mode in which each of the tines twists about a respective axis extending in the horizontal lengthwise direction.

Abstract: Disclosed are an acylphosphine oxide compound and a preparation method therefor, which belong to the field of initiators. The method comprises: reacting compound B and compound C under the conditions of an organic base and an organic solvent so as to obtain the acylphosphine oxide compound. The chemical structural formula of compound B is as follows: the chemical structural formula of compound C is as follows: and the chemical structural formula of the acyl phosphine oxide compound is as follows: wherein R1 is hydrogen, a C1-C6 alkyl group, methoxy, methylthio, dimethylamino, chloroformyl, phenyl, benzoyl, (4-dimethylamino) phenyl, ?-naphthyl, ?-naphthyl or (9-ethyl-9H-carbazole)-3-yl, R2 and R1 are the same, n is the substitution number of R1 on the corresponding phenyl ring, and is 1, 2 or 3, and m is the substitution number of R2 on the corresponding phenyl ring, and is 1, 2 or 3. The preparation method is safe and environmentally friendly, and has a high yield.

Abstract: The disclosed technology generally relates to quartz crystal devices and more particularly to quartz crystal devices configured to vibrate in torsional mode. In one aspect, a quartz crystal device configured for temperature sensing comprises a fork-shaped quartz crystal comprising a pair of elongate tines laterally extending from a base region in a horizontal lengthwise direction of the fork-shaped quartz crystal, wherein each of the tines has formed on one or both of opposing sides thereof a pair of vertically recessed groove structures laterally elongated in the horizontal lengthwise direction, wherein the pair of groove structures are separated in a horizontal widthwise direction by a line structure.

Abstract: The present application provides a display panel, a manufacturing method and an intelligent wearable device of flexible organic light-emitting diode (OLED). The display panel includes a conductive layer and a metallic anode layer disposed at one side of the conductive layer, wherein a material of the conductive layer is a mixture of silver-nanowires and polymethyl methacrylate (PMMA).

Abstract: An EtherCAT master-slave station integrated bridge controller, a control method, a control system and a readable storage medium are provided. Therein, an FPGA-based EtherCAT master-slave station integrated bridge controller is constructed. Because of the hardware parallel computing capability of FPGA, the master station of the EtherCAT master-slave station integrated bridge controller has a hard real-time characteristic so as to ensure real-time sending and receiving of EtherCAT network data and reduce the dependence on CPU performance and operating system real-time performance. The EtherCAT master-slave station integrated bridge controller can serve as a slave device relative to a third-party master station device and meanwhile serve as a master device relative to a third-party slave station device, thus reducing the load of EtherCAT bus network and improving the flexibility of network topology.

Abstract: A composite photoalignment layer for aligning liquid crystal molecules includes: a monomeric material; a photoinitiator or a thermal initiator; and an azo dye material. A method for preparing a composite photoalignment layer for aligning liquid crystal molecules includes: mixing, in solution form, a monomeric material, a photoinitiator or a thermal initiator, and an azo dye material; coating the mixed solution onto a substrate to form a thin film; exposing the thin film to polarized light; and, with a thermal initiator, heating the thin film to polymerize the monomeric material and form a solid thin film.

Abstract: In an approach for detecting key messages for a video, a processor builds a role model based on data from one or more data sources, with an identification feature of each role in a video. A processor samples a plurality of frames of the video. A processor identifies a key object presented in the plurality of frames. The key object is a role in the video. A processor recognizes a movement scenario associated with the role. A processor dynamically updates the role model based on the movement scenario. A processor identifies a role name based on the movement scenario. A processor generates a description script associated with the movement scenario for the role. A processor outputs the description script.

Abstract: A method of partitioning in video coding for JVET, comprising representing a JVET coding tree unit as a root node in a quadtree plus binary tree (QTBT structure that can have quadtree or binary partitioning of the root node and quadtree or binary trees branching from each of the leaf nodes. The partitioning at any depth can use asymmetric binary partitioning to split a child node represented by a leaf node into two child coding units of unequal size, representing the two child coding units as leaf nodes in a binary tree branching from the parent leaf node and coding the child coding units represented by final leaf nodes of the binary tree with JVET. Disclosed is a generalized method of partitioning a block, either square or rectangular, which leads to more flexible block sizes with possible higher coding efficiency.

Abstract: A compressor includes a housing, and an anticorrosive coating covering a surface of the housing. The anticorrosive coating includes a base layer applied on the surface of the housing, and a surface layer applied on the base layer. Both the base layer and the surface layer are organic coatings. Thus, the housing of the compressor is effectively separated from the external environment by means of the two organic coatings, so as to ensure that the compressor is not corroded; moreover, the anticorrosive coating does not contain a metal coating, thereby preventing the problem of the compressor being severely corroded due to an exposed metal coating.

Abstract: A measurement gap indication method includes: obtaining indication information of whether a measurement gap is required when a user equipment operates with a target parameter; and transmitting the indication information to a network device. The target parameter includes at least one of carrier, carrier frequency band combination, bandwidth part, bandwidth part combination and reference signal.