Abstract: A GIP and GLP-1 dual receptor agonist, a pharmaceutical composition, and the use. In particular, the present application relates to a compound represented by formula I, a pharmaceutical composition comprising the compound, and the use of the compound as a GIP and GLP-1 dual receptor agonist in the field of medicine. The compound represented by formula I exhibits excellent GIPR and GLP-1R agonist activity and excellent pharmaceutical activity in reducing blood sugar and controlling body weight, is a therapeutic drug having a clinical application prospect, and can be used for preventing and treating diseases such as diabetes, diabetes complications, obesity, or obesity complications.

Abstract: A display substrate and a display device. The display substrate includes a display region, a first connecting wire, and a second connecting wire. A first display region includes a first sub-pixel array, including a plurality of light emitting elements arranged in an array, and the plurality of light emitting elements include a first light emitting element and a second light emitting element. The second display region includes a first pixel circuit array, including a plurality of first pixel circuit units, and the plurality of pixel circuit units include a first pixel circuit (D10) and a second pixel circuit. The first connecting wire (151) is connected to the first pixel circuit and the first light emitting element. The second connecting wire is connected to the second pixel circuit and the second light emitting element. The second connecting wire extends in a first direction, the first connecting wire extends in a second direction.

Abstract: A display substrate and a display device. The display substrate includes a display region, a first connecting wire and a second connecting wire. The display region includes a first display region and a second display region. The first display region includes a plurality of light emitting devices arranged in an array, and the plurality of light emitting devices includes a first light emitting device and a second light emitting device. The second display region includes a plurality of first pixel circuit units, and the plurality of pixel circuit units includes a first pixel circuit and a second pixel circuit. The first connecting wire is connected to the first pixel circuit and the first light emitting device. The second connecting wire is connected to the second pixel circuit and the second light emitting device. The first direction and the second direction intersect each other.

Abstract: A display substrate and a manufacturing method thereof, and a display device are provided. The display substrate includes a base substrate, including a pixel array region and a peripheral region; and a first scan driving circuit, a plurality of power lines, a first signal line group, and a second signal line group, which are in the peripheral region and located on a first side of the base substrate. The first scan driving circuit includes a plurality of cascaded first shift registers; the plurality of power lines are configured to provide a plurality of power voltages to the plurality of cascaded first shift registers in the first scan driving circuit; the first signal line group includes at least one timing signal line; and the second signal line group is on a side of the plurality of power lines and the first signal line group away from the pixel array region.

Abstract: The present disclosure provides an array substrate and a display device. The array substrate includes: a sub-pixel, in a display region and including a light-emitting element, the light-emitting element including a first electrode, a light-emitting layer and a second electrode; a positive power line, connected to the first electrode; a positive power bus, connected to the positive power line; three positive power access ends, at a side of the positive power bus away from a display region, and respectively connected to the positive power bus; a negative power line; an auxiliary electrode, respectively connected to the negative power line and the second electrode; three negative power access ends, at the side of the positive power bus away from the display region, and respectively connected to the negative power line; and a negative power auxiliary line, respectively connected to the negative power access end and the auxiliary electrode.

Abstract: A system for testing an assist function of electric vehicle wireless power transfer includes: a pit, a vehicle-assembly support platform, and an electromagnetic field strength measurement instrument. A ground-assembly support platform is arranged inside the pit, the vehicle-assembly support platform is arranged on an upper side of the ground-assembly support platform, and a to-be-tested member is arranged on an upper side of the ground-assembly support platform. A ground-assembly device coil is arranged on an upper surface of the ground-assembly support platform, a vehicle-assembly device coil is arranged inside the vehicle-assembly support platform, the ground-assembly device coil charges an entire vehicle, and the ground-assembly device coil further cooperates with the vehicle-assembly device coil to charge a vehicle component. A mechanical arm is arranged on ground of a test site, an interference member is arranged on a front end of the mechanical arm.

Abstract: A display panel and a display device, the display panel comprising: a first display region; a second display region, at least partially positioned on one side of the first display region; a plurality of pixel units, the density of pixel units in the first display region being less than the density of pixel units in the second display region, and the pixel units comprising pixel circuits; and first power supply lines, configured to supply a first voltage signal to the pixel circuits. The first power supply lines comprise a plurality of first wires, a plurality of second wires, and a plurality of third wires, the first wires extending from the second display region to the first display region, the plurality of second wires being positioned in the first display region, positioned between adjacent first wires, and extending in a first direction, and the third wires extending along a second direction, the first direction intersecting with the second direction.

Abstract: A display substrate and a manufacturing method thereof, and a display device are provided. The display substrate includes a base substrate, a gate driving circuit, power lines, a first signal line group, and a second signal line group. The gate driving circuit includes cascaded shift register units; the power lines are configured to provide power signals to the shift register units; the first signal line group includes at least one clock signal line, and the clock signal line is configured to provide a clock signal to the shift register units; the second signal line group includes a trigger signal line, and the trigger signal line is configured to provide a trigger signal to a first-stage shift register unit; and the gate driving circuit includes at least one transistor, and an extending direction of a channel of the transistor is parallel to an extending direction of the clock signal line.

Abstract: Provided is a display substrate including a base substrate, a plurality of pixel units, at least one first power line, a barrier structure, an adapting structure, a cathode layer and a first organic pattern. By covering at least part of the second side face of the adapting structure with the first organic pattern, the risk of the second side face of the adapting structure being eroded by moisture or oxygen due to the etching defects can be reduced.

Abstract: Embodiments of this disclosure provide a method for starting an application and a related apparatus. The method includes the following: A user terminal may acquire a configuration parameter of a target application from a data management server when a start instruction for the target application is detected. The configuration parameter includes plugin configuration information and code package configuration information. The target application can be executed by using a target code package and a locally cached target plugin.

Abstract: The present invention discloses a fabrication method and use of a ?40 mm large-size and high-contrast fiber optic image inverter, belonging to the field of manufacturing of fiber optic imaging elements. The light-absorbing glass for preparing the ?40 mm large-size and high-contrast fiber optic image inverter consists of the following components in molar percentage: SiO2 60-69.9, Al2O3 1.0-10.0, B2O3 10.1-15.0, Na2O 1.0-8.0, K2O 3.0-10.0, MgO 0.1-1.0, CaO 0.5-5.0, ZnO 0-0.1, TiO2 0-0.1, ZrO2 0.1-1.0, Fe2O3 3.0-6.5, Co2O3 0.1-0.5, V2O5 0.51-1.5 and MoO3 0.1-1.0. The fiber optic image inverter has the advantages of low crosstalk of stray light, high resolution and high contrast.

Abstract: A system for testing an assist function of electric vehicle wireless power transfer includes: a pit, a vehicle-assembly support platform, and an electromagnetic field strength measurement instrument. A ground-assembly support platform is arranged inside the pit, the vehicle-assembly support platform is arranged on an upper side of the ground-assembly support platform, and a to-be-tested member is arranged on an upper side of the ground-assembly support platform. A ground-assembly device coil is arranged on an upper surface of the ground-assembly support platform, a vehicle-assembly device coil is arranged inside the vehicle-assembly support platform, the ground-assembly device coil charges an entire vehicle, and the ground-assembly device coil further cooperates with the vehicle-assembly device coil to charge a vehicle component. A mechanical arm is arranged on ground of a test site, an interference member is arranged on a front end of the mechanical arm.

Abstract: Provided are a display panel and a display device. The display panel includes: a base substrate; light-emitting elements including groups of light-emitting elements, at least one group of light-emitting elements including first-region light-emitting elements and second-region light-emitting elements; pixel circuits including groups of pixel circuits, at least one group of pixel circuits including first-type pixel circuits and second-type pixel circuits, at least one second-type pixel circuit is connected with at least one second-region light-emitting element through a conductive line, first light-emitting elements are connected with first pixel circuits through first conductive lines, in the at least one group of light-emitting elements and the at least one group of pixel circuits, first pixel circuits connected with first light-emitting elements are closer to the second display region than each of second pixel circuits connected with second light-emitting elements.

Abstract: A display substrate. In a plane parallel to the display substrate, the display substrate includes a plurality of sub-pixels, at least one sub-pixel includes a pixel driving circuit and a light emitting device connected to the pixel driving circuit, the pixel driving circuit at least includes a storage capacitor and a plurality of transistors, the plurality of transistors at least includes a driving transistor and at least one switching transistor of a dual-gate structure. In a plane perpendicular to the display substrate, the display substrate includes a plurality of conductive layers, the first polar plate and the gate electrode of the drive transistor are arranged in the same layer, the second polar plate and the first power line are arranged in the same layer.

Abstract: Provided is a display panel. The display panel includes: a substrate, at least one row of light-emitting elements disposed on the substrate, a plurality of pixel drive circuits, a plurality of connection lines, and a plurality of compensation portions. A length of a first connection line electrically connected to a first pixel drive circuit is less than a length of a second connection line electrically connected to a second pixel drive circuit. A capacitance of the first connection line is compensated by electrically connecting the compensation portion to the first connection line, and thus a difference between the capacitance of the first connection line and a capacitance of the second connection line is reduced.

Abstract: Provided is a GII.4 norovirus virus-like particle or active fragment thereof, and use thereof, the virus-like particle comprising or being composed of an amino acid sequence shown as SEQ ID NO: 4. Further, provided is a composition or a kit comprising the GII.4 norovirus virus-like particle, and use thereof. The objective of covering multiple genotypes is achieved by using a single antigen of the invention, the process difficulty of the preparation for a pharmaceutical composition or a vaccine can be reduced, and the production cost is decreased. Also, provided is a norovirus immune composition or a kit comprising GII.2, GII.4, GII.6, and GII.17 norovirus virus-like particles or active fragments thereof, and use thereof.

Abstract: A display substrate and a display device are provided. In the display substrate, a first display region includes a first light emitting unit column and a second light emitting unit column each connected with a column of first sub-pixel circuits; a second display region includes a third light emitting unit column and a fourth light emitting unit column each connected with a column of first sub-pixel circuit pairs; each second sub data line is connected with each second light emitting unit column, and each fourth sub data line is connected with each fourth light emitting unit column. The first sub-pixel circuits connected with the fourth light emitting unit column and the first sub-pixel circuits connected with the second light emitting unit column are located in different columns, and the second sub data line and the fourth sub data line are connected by a data line connection portion.

Abstract: A display panel and a display device are provided. In an embodiment, the display panel has a display region and a non-display region and includes shift registers cascaded and arranged along a first direction. In an embodiment, the shift registers are located in the non-display region. In an embodiment, one of the shift registers includes a switch module and an output module. In an embodiment, the output module is coupled to an output terminal of the shift register and includes two output transistors, and the output transistors are located at a side of the switch module away from the display region. In this way, the probability of occurrence of abnormal phenomena, such as splash screen display, is reduced.